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AT2G47510.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
mitochondrion 1.000
ASURE: mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31911558 (2020): mitochondrion
  • PMID:31871212 (2020): mitochondrion
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31023727 (2019): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:24727099 (2014): mitochondrion
  • PMID:23750852 (2013): mitochondrion
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23444301 (2013): mitochondrion
  • PMID:23444301 (2013): mitochondrion mitochondrial matrix
  • PMID:22923678 (2012): mitochondrion
  • PMID:22550958 (2012): plastid
  • PMID:22540835 (2012): mitochondrion
  • PMID:21841088 (2011): mitochondrion
  • PMID:21472856 (2011): mitochondrion
  • PMID:21311031 (2011): mitochondrion
  • PMID:18385124 (2008): mitochondrion
  • PMID:14671022 (2004): mitochondrion
  • PMID:12492832 (2002): mitochondrion
  • PMID:11743115 (2001): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : fumarase 1
Curator
Summary (TAIR10)
Encodes a mitochondrial-localized protein. The FUM1 gene appears to be essential, suggesting that FUM1 may play a crucial role as a fumarase in the tricarboxylic acid cycle.
Computational
Description (TAIR10)
fumarase 1 (FUM1); FUNCTIONS IN: fumarate hydratase activity, protein binding; INVOLVED IN: response to oxidative stress, response to salt stress, pollen tube development; LOCATED IN: mitochondrion; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seed development stages; CONTAINS InterPro DOMAIN/s: Fumarate hydratase, class II (InterPro:IPR005677), L-Aspartase-like (InterPro:IPR008948), Fumarate lyase, conserved site (InterPro:IPR020557), Lyase 1, N-terminal (InterPro:IPR022761), Fumarase C, C-terminal (InterPro:IPR018951), Fumarate lyase (InterPro:IPR000362); BEST Arabidopsis thaliana protein match is: FUMARASE 2 (TAIR:AT5G50950.2); Has 19736 Blast hits to 19727 proteins in 2822 species: Archae - 389; Bacteria - 12991; Metazoa - 306; Fungi - 295; Plants - 106; Viruses - 0; Other Eukaryotes - 5649 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1578-MONOMERBioGrid:4699BRENDA:4.2.1.2EC:4.2.1.2
eggNOG:COG0114eggNOG:KOG1317EMBL:AC002535EMBL:AF020303
EMBL:AY054252EMBL:AY062460EMBL:BT003361EMBL:CP002685
EMBL:U82202EnsemblPlants:AT2G47510EnsemblPlants:AT2G47510.1EnsemblPlants:AT2G47510.2
entrez:819364Gene3D:1.10.275.10GeneID:819364Genevisible:P93033
GO:GO:0004333GO:GO:0005739GO:GO:0005829GO:GO:0006099
GO:GO:0006106GO:GO:0006108GO:GO:0006979GO:GO:0009651
GO:GO:0045239GO:GO:0048868GO:GO:0051262Gramene:AT2G47510.1
Gramene:AT2G47510.2gramene_pathway:4.2.1.2gramene_pathway:PWY-561gramene_pathway:PWY-5690
gramene_pathway:PWYQT-4481gramene_plant_reactome:1119533gramene_plant_reactome:6876687HAMAP:MF_00743
hmmpanther:PTHR11444hmmpanther:PTHR11444:SF1HOGENOM:HOG000061736InParanoid:P93033
IntAct:P93033InterPro:IPR000362InterPro:IPR005677InterPro:IPR008948
InterPro:IPR018951InterPro:IPR020557InterPro:IPR022761InterPro:IPR024083
KEGG:00020+4.2.1.2KEGG:00620+4.2.1.2KEGG:00720+4.2.1.2KEGG:ath:AT2G47510
KO:K01679OMA:DESERMPPANTHER:PTHR11444PaxDb:P93033
Pfam:P93033Pfam:PF00206Pfam:PF10415PhylomeDB:P93033
PIR:T00433PRIDE:P93033PRINTS:PR00149PRO:PR:P93033
PROSITE:PS00163ProteinModelPortal:P93033Proteomes:UP000006548Reactome:R-ATH-71403
RefSeq:NP_001078075.1RefSeq:NP_182273.1scanprosite:PS00163SMR:P93033
STRING:3702.AT2G47510.1SUPFAM:SSF48557SwissPalm:P93033TAIR:AT2G47510
tair10-symbols:FUM1TIGRfam:TIGR00979TIGRFAMs:TIGR00979UniGene:At.10398
UniPathway:UPA00223UniProt:P93033
Coordinates (TAIR10) chr2:+:19498614..19502020
Molecular Weight (calculated) 53002.60 Da
IEP (calculated) 7.98
GRAVY (calculated) -0.17
Length 492 amino acids
Sequence (TAIR10)
(BLAST)
001: MSIYVASRRL SGGTTVTALR YATSLRSYST SFREERDTFG PIQVPSDKLW GAQTQRSLQN FEIGGERERM PEPIVRAFGV LKKCAAKVNM EYGLDPTIGK
101: AIMQAAQEVA EGKLNDHFPL VVWQTGSGTQ SNMNANEVIA NRAAEILGRK RGEKCVHPND HVNRSQSSND TFPTVMHIAA ATEINSRLIP SLKTLHSTLE
201: SKSFEFKDIV KIGRTHTQDA TPLTLGQEFG GYATQVKYGL NRVTCTLPRL YQLAQGGTAV GTGLNTKKGF DVKIAAAVAE ETNLPFVTAE NKFEALAAHD
301: ACVETSGSLN TIATSLMKIA NDIRFLGSGP RCGLGELVLP ENEPGSSIMP GKVNPTQCEA LTMVCAQVMG NHVAVTVGGS NGHFELNVFK PVIASALLHS
401: VRLIADASAS FEKNCVRGIE ANRERISKLL HESLMLVTSL NPKIGYDNAA AVAKKAHKEG CTLKEAALNL GVLTAEEFDT LVVPEKMIGP SD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)