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AT1G65930.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31975158 (2020): plastid
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:30394608 (2019): plastid
  • PMID:30135097 (2018): plastid
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25641898 (2015): plasma membrane
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22574745 (2012): mitochondrion
  • PMID:22318864 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21311031 (2011): mitochondrion
  • PMID:21166475 (2011): cytosol
  • PMID:20061580 (2010): plastid plastid stroma
  • PMID:19334764 (2009): plasma membrane
  • PMID:17644812 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cytosolic NADP+-dependent isocitrate dehydrogenase
Curator
Summary (TAIR10)
Encodes a NADP+-isocitrate dehydrogenase that is believed to function in the cytosol. It appears to contribute to NADPH production under oxidative stress, and thereby to participate in redox signalling linked to defense responses.
Computational
Description (TAIR10)
cytosolic NADP+-dependent isocitrate dehydrogenase (cICDH); FUNCTIONS IN: isocitrate dehydrogenase (NADP+) activity, copper ion binding; INVOLVED IN: in 7 processes; LOCATED IN: cytosol, apoplast, plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate dehydrogenase NADP-dependent, eukaryotic (InterPro:IPR004790), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isocitrate dehydrogenase (TAIR:AT1G54340.1); Has 5437 Blast hits to 5413 proteins in 1130 species: Archae - 48; Bacteria - 1243; Metazoa - 817; Fungi - 231; Plants - 475; Viruses - 0; Other Eukaryotes - 2623 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT1G65930-MONOMERBioGrid:28126BRENDA:1.1.1.42EC:1.1.1.42
eggNOG:COG0538eggNOG:KOG1526EMBL:AC009513EMBL:AF419575
EMBL:AJ437268EMBL:AY045631EMBL:AY088129EMBL:AY093091
EMBL:AY097340EMBL:BT002400EMBL:CP002684EnsemblPlants:AT1G65930
EnsemblPlants:AT1G65930.1entrez:842905Gene3D:3.40.718.10GeneID:842905
Genevisible:Q9SRZ6GO:GO:0000287GO:GO:0004450GO:GO:0005507
GO:GO:0005829GO:GO:0005886GO:GO:0006099GO:GO:0006102
GO:GO:0006739GO:GO:0009506GO:GO:0009570GO:GO:0009651
GO:GO:0010043GO:GO:0042742GO:GO:0046686GO:GO:0048046
GO:GO:0051287Gramene:AT1G65930.1gramene_pathway:1.1.1.42gramene_pathway:PWY-6549
hmmpanther:PTHR11822HOGENOM:HOG000019858InParanoid:Q9SRZ6IntAct:Q9SRZ6
InterPro:IPR004790InterPro:IPR019818InterPro:IPR024084iPTMnet:Q9SRZ6
KEGG:00020+1.1.1.42KEGG:00480+1.1.1.42KEGG:00720+1.1.1.42KEGG:ath:AT1G65930
KO:K00031OMA:DETYASEPANTHER:PTHR11822PaxDb:Q9SRZ6
Pfam:PF00180Pfam:Q9SRZ6PhylomeDB:Q9SRZ6PIR:F96683
PIRSF:PIRSF000108PRIDE:Q9SRZ6PRO:PR:Q9SRZ6PROSITE:PS00470
ProteinModelPortal:Q9SRZ6Proteomes:UP000006548Reactome:R-ATH-389542Reactome:R-ATH-71403
RefSeq:NP_176768.1scanprosite:PS00470SMART:SM01329SMR:Q9SRZ6
STRING:3702.AT1G65930.1SUPFAM:SSF53659TAIR:AT1G65930tair10-symbols:cICDH
TIGRfam:TIGR00127TIGRFAMs:TIGR00127UniGene:At.24713UniProt:Q9SRZ6
Coordinates (TAIR10) chr1:+:24539088..24541861
Molecular Weight (calculated) 45748.60 Da
IEP (calculated) 6.52
GRAVY (calculated) -0.32
Length 410 amino acids
Sequence (TAIR10)
(BLAST)
001: MAFEKIKVAN PIVEMDGDEM TRVIWKSIKD KLITPFVELD IKYFDLGLPH RDATDDKVTI ESAEATKKYN VAIKCATITP DEGRVTEFGL KQMWRSPNGT
101: IRNILNGTVF REPIICKNVP KLVPGWTKPI CIGRHAFGDQ YRATDAVIKG PGKLTMTFEG KDGKTETEVF TFTGEGGVAM AMYNTDESIR AFADASMNTA
201: YEKKWPLYLS TKNTILKKYD GRFKDIFQEV YEASWKSKYD AAGIWYEHRL IDDMVAYALK SEGGYVWACK NYDGDVQSDF LAQGFGSLGL MTSVLVCPDG
301: KTIEAEAAHG TVTRHFRVHQ KGGETSTNSI ASIFAWTRGL AHRAKLDDNA KLLDFTEKLE AACVGTVESG KMTKDLALII HGSKLSRDTY LNTEEFIDAV
401: AAELKERLNA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)