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AT1G75950.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:21166475 (2011): cytosol
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : S phase kinase-associated protein 1
Curator
Summary (TAIR10)
SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.
Computational
Description (TAIR10)
S phase kinase-associated protein 1 (SKP1); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, male meiosis, ubiquitin-dependent protein catabolic process; LOCATED IN: in 7 components; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 family protein (TAIR:AT5G42190.1); Has 1455 Blast hits to 1451 proteins in 268 species: Archae - 0; Bacteria - 0; Metazoa - 552; Fungi - 179; Plants - 538; Viruses - 11; Other Eukaryotes - 175 (source: NCBI BLink).
Protein Annotations
BioGrid:29147DIP:DIP-31325NeggNOG:COG5201eggNOG:KOG1724EMBL:AC007396EMBL:AF059294EMBL:AY080884
EMBL:AY113971EMBL:CP002684EMBL:U60981EMBL:U70034EMBL:U97020EnsemblPlants:AT1G75950EnsemblPlants:AT1G75950.1
entrez:843928EvolutionaryTrace:Q39255GeneID:843928Genevisible:Q39255GO:GO:0000226GO:GO:0005634GO:GO:0005819
GO:GO:0005829GO:GO:0005886GO:GO:0006511GO:GO:0007059GO:GO:0007275GO:GO:0009524GO:GO:0009734
GO:GO:0009873GO:GO:0016032GO:GO:0016567GO:GO:0045910GO:GO:0046686Gramene:AT1G75950.1hmmpanther:PTHR11165
HOGENOM:HOG000172184InParanoid:Q39255IntAct:Q39255InterPro:IPR001232InterPro:IPR011333InterPro:IPR016072InterPro:IPR016073
InterPro:IPR016897iPTMnet:Q39255KEGG:ath:AT1G75950KO:K03094OMA:ANMMMCKPaxDb:Q39255PDB:2P1M
PDB:2P1NPDB:2P1OPDB:2P1PPDB:2P1QPDB:3C6NPDB:3C6OPDB:3C6P
PDB:3OGKPDB:3OGLPDB:3OGMPDBsum:2P1MPDBsum:2P1NPDBsum:2P1OPDBsum:2P1P
PDBsum:2P1QPDBsum:3C6NPDBsum:3C6OPDBsum:3C6PPDBsum:3OGKPDBsum:3OGLPDBsum:3OGM
Pfam:PF01466Pfam:PF03931Pfam:Q39255PhylomeDB:Q39255PIR:T51309PIRSF:PIRSF028729PRIDE:Q39255
PRO:PR:Q39255ProteinModelPortal:Q39255Proteomes:UP000006548RefSeq:NP_565123.1SMART:SM00512SMR:Q39255STRING:3702.AT1G75950.1
SUPFAM:SSF54695SUPFAM:SSF81382SwissPalm:Q39255TAIR:AT1G75950tair10-symbols:ASK1tair10-symbols:ATSKP1tair10-symbols:SKP1
tair10-symbols:SKP1Atair10-symbols:UIP1UniGene:At.23531UniPathway:UPA00143UniProt:Q39255
Coordinates (TAIR10) chr1:+:28516715..28517454
Molecular Weight (calculated) 17858.00 Da
IEP (calculated) 4.17
GRAVY (calculated) -0.32
Length 160 amino acids
Sequence (TAIR10)
(BLAST)
001: MSAKKIVLKS SDGESFEVEE AVALESQTIA HMVEDDCVDN GVPLPNVTSK ILAKVIEYCK RHVEAAASKA EAVEGAATSD DDLKAWDADF MKIDQATLFE
101: LILAANYLNI KNLLDLTCQT VADMIKGKTP EEIRTTFNIK NDFTPEEEEE VRRENQWAFE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)