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AT1G04250.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
FP Images

7-day old Arabidopsis seedling (no marker)

RFP-At1g04250
(full-length)
overlay

SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : AUX/IAA transcriptional regulator family protein
Curator
Summary (TAIR10)
Transcription regulator acting as repressor of auxin-inducible gene expression. Auxin-inducible AUX/IAA gene. Short-lived nuclear protein with four conserved domains. Domain III has homology to beta alpha alpha dimerization and DNA binding domains. Involved in auxin signaling. Auxin induces the degradation of the protein in a dosage-dependent manner in a process mediated by AtRac1. Auxin induced the relocalization of the protein within the nucleus from a diffused nucleoplasmic pattern to a discrete particulated pattern named nuclear protein bodies or NPB in a process also mediated by Rac1. Colocalizes with SCF, CSN and 26S proteasome components.
Computational
Description (TAIR10)
AUXIN RESISTANT 3 (AXR3); CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: indole-3-acetic acid inducible 14 (TAIR:AT4G14550.1); Has 1763 Blast hits to 1762 proteins in 78 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1762; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).
Protein Annotations
BioGrid:24803DNASU:839568eggNOG:ENOG410JVDBeggNOG:ENOG411060MEMBL:AC000104EMBL:AF040631EMBL:AF040632
EMBL:AF336916EMBL:AY070094EMBL:AY087284EMBL:AY117183EMBL:CP002684EMBL:U49073EnsemblPlants:AT1G04250
EnsemblPlants:AT1G04250.1entrez:839568GeneID:839568Genevisible:P93830GO:GO:0003700GO:GO:0005634GO:GO:0006351
GO:GO:0009733GO:GO:0009734GO:GO:0042802GO:GO:1900057Gramene:AT1G04250.1hmmpanther:PTHR31734hmmpanther:PTHR31734:SF30
HOGENOM:HOG000238261InParanoid:P93830IntAct:P93830InterPro:IPR000270InterPro:IPR003311InterPro:IPR033389KEGG:ath:AT1G04250
KO:K14484MINT:MINT-8067258OMA:KEGSTTHPANTHER:PTHR31734PaxDb:P93830PDB:2MUKPDBsum:2MUK
Pfam:P93830Pfam:PF02309Pfscan:PS51745PhylomeDB:P93830PIR:H86173PRIDE:P93830PRO:PR:P93830
PROSITE:PS51745ProteinModelPortal:P93830Proteomes:UP000006548RefSeq:NP_171921.1SMR:P93830STRING:3702.AT1G04250.1SUPFAM:SSF54277
TAIR:AT1G04250tair10-symbols:AXR3tair10-symbols:IAA17UniGene:At.20252UniProt:P93830
Coordinates (TAIR10) chr1:+:1136382..1138340
Molecular Weight (calculated) 25289.40 Da
IEP (calculated) 7.25
GRAVY (calculated) -0.48
Length 229 amino acids
Sequence (TAIR10)
(BLAST)
001: MMGSVELNLR ETELCLGLPG GDTVAPVTGN KRGFSETVDL KLNLNNEPAN KEGSTTHDVV TFDSKEKSAC PKDPAKPPAK AQVVGWPPVR SYRKNVMVSC
101: QKSSGGPEAA AFVKVSMDGA PYLRKIDLRM YKSYDELSNA LSNMFSSFTM GKHGGEEGMI DFMNERKLMD LVNSWDYVPS YEDKDGDWML VGDVPWPMFV
201: DTCKRLRLMK GSDAIGLAPR AMEKCKSRA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)