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AT1G66750.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.923
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : CDK-activating kinase 4
Curator
Summary (TAIR10)
Computational
Description (TAIR10)
CDK-activating kinase 4 (CAK4); FUNCTIONS IN: protein binding, protein serine/threonine kinase activity, kinase activity; INVOLVED IN: regulation of cyclin-dependent protein kinase activity; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cyclin-dependent kinase D1;1 (TAIR:AT1G73690.1); Has 124001 Blast hits to 122583 proteins in 4490 species: Archae - 94; Bacteria - 13930; Metazoa - 46186; Fungi - 12564; Plants - 30685; Viruses - 410; Other Eukaryotes - 20132 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G66750-MONOMERBioGrid:28214EC:2.7.11.22EC:2.7.11.23
eggNOG:ENOG410XQDHeggNOG:KOG0659EMBL:AB074116EMBL:AC013288
EMBL:AY136355EMBL:BT000198EMBL:CP002684EnsemblPlants:AT1G66750
EnsemblPlants:AT1G66750.1entrez:842993GeneID:842993Genevisible:Q9C9M7
GO:GO:0000079GO:GO:0004674GO:GO:0004693GO:GO:0005524
GO:GO:0005634GO:GO:0005737GO:GO:0007049GO:GO:0008353
GO:GO:0051301Gramene:AT1G66750.1hmmpanther:PTHR24056hmmpanther:PTHR24056:SF0
HOGENOM:HOG000233024InParanoid:Q9C9M7IntAct:Q9C9M7InterPro:IPR000719
InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441iPTMnet:Q9C9M7
KEGG:ath:AT1G66750KO:K02202OMA:KAADRYLPaxDb:Q9C9M7
Pfam:PF00069Pfam:Q9C9M7Pfscan:PS50011PhylomeDB:Q9C9M7
PRIDE:Q9C9M7PRO:PR:Q9C9M7PROSITE:PS00107PROSITE:PS00108
PROSITE:PS50011ProteinModelPortal:Q9C9M7Proteomes:UP000006548Reactome:R-ATH-113418
Reactome:R-ATH-5696395Reactome:R-ATH-674695Reactome:R-ATH-6781823Reactome:R-ATH-6782135
Reactome:R-ATH-6782210Reactome:R-ATH-69273Reactome:R-ATH-69656Reactome:R-ATH-72086
Reactome:R-ATH-73776Reactome:R-ATH-73779Reactome:R-ATH-75953Reactome:R-ATH-76042
Reactome:R-ATH-77075RefSeq:NP_176847.1scanprosite:PS00107scanprosite:PS00108
SMART:SM00220SMR:Q9C9M7STRING:3702.AT1G66750.1SUPFAM:SSF56112
TAIR:AT1G66750tair10-symbols:AT;CDKD;2tair10-symbols:CAK4tair10-symbols:CAK4AT
tair10-symbols:CDKD1;2tair10-symbols:CDKD;2UniGene:At.35737UniProt:Q9C9M7
Coordinates (TAIR10) chr1:+:24894775..24897015
Molecular Weight (calculated) 39203.40 Da
IEP (calculated) 9.46
GRAVY (calculated) -0.31
Length 348 amino acids
Sequence (TAIR10)
(BLAST)
001: MSKSGDNQPV DRYLRRQILG EGTYGVVYKA TDTKTGKTVA VKKIRLGNQK EGVNFTALRE IKLLKELNHP HIVELIDAFP HDGSLHLVFE YMQTDLEAVI
101: RDRNIFLSPG DIKSYMLMTL KGLAYCHKKW VLHRDMKPNN LLIGENGLLK LADFGLARLF GSPNRRFTHQ VFATWYRAPE LLFGSRQYGA GVDVWAAGCI
201: FAELLLRRPF LPGSTEIDQL GKIFQAFGTP VPSQWSDMIY LPDYMEFSYT PAPPLRTIFP MASDDALDLL AKMFIYDPRQ RITIQQALDH RYFSSSPSPT
301: EPGKLQIPAS KGDALEPKAS EQNQHGNSPA VLSPPGKMRR VMGPEGFT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)