AT3G52560.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.821 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : ubiquitin E2 variant 1D-4 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
MMZ4/UEV1D encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UEV1D can form diubiquitin and triubiquitin chains in combination with UBC13A/UBC35 in vitro. It can also functionally complement an mms2 mutation in budding yeast, both by increasing mms2 mutant viability in the presence of the DNA damaging agent MMS, and by reducing the rate of spontaneous DNA mutation. It can also rescue an mms2 ubc13 double mutant in yeast in combination with UBC13A. MMZ4/UEV1D transcripts are found in most plant organs, like the other three MMZ/UEV1 family members, but it is normally present at higher levels. In addition, MMZ4/UEV1D is the only family member whose transcripts are detected in pollen. However, MMZ4/UEV1D transcript levels do not appear to be stress-inducible. uev1d-1 mutants are more sensitive than wild type plants to the DNA damaging agent MMS in seed germination and pollen germination assays. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.1); Has 2665 Blast hits to 2665 proteins in 275 species: Archae - 0; Bacteria - 0; Metazoa - 1316; Fungi - 370; Plants - 595; Viruses - 0; Other Eukaryotes - 384 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:-:19494678..19495954 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 16533.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.67 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.56 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 146 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MTLGSGGSSV VVPRNFRLLE ELERGEKGIG DGTVSYGMDD GDDIYMRSWT GTIIGPHNTV HEGRIYQLKL FCDKDYPEKP PTVRFHSRVN MACVNHETGV 101: VDPKKFGLLA NWQREYTMED ILVQLKKEMS TSHNRKLVQP PEGTCF |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)