AT3G19150.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : KIP-related protein 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
KIP-related protein 6 (KRP6); FUNCTIONS IN: cyclin binding, cyclin-dependent protein kinase inhibitor activity; INVOLVED IN: negative regulation of cyclin-dependent protein kinase activity, DNA endoreduplication; LOCATED IN: nucleus; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: D pollen mother cell meiosis stage, C tetrad of megaspores, B meiosis of megaspore mother cell; CONTAINS InterPro DOMAIN/s: Cyclin-dependent kinase inhibitor, plant (InterPro:IPR016701), Cyclin-dependent kinase inhibitor (InterPro:IPR003175); BEST Arabidopsis thaliana protein match is: Cyclin-dependent kinase inhibitor family protein (TAIR:AT1G49620.1); Has 1712 Blast hits to 484 proteins in 111 species: Archae - 0; Bacteria - 136; Metazoa - 266; Fungi - 200; Plants - 207; Viruses - 3; Other Eukaryotes - 900 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr3:-:6616628..6617655 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 21455.20 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.24 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.79 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 196 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MSERKRELAE EASSTSFSPL KKTKLNDSSD SSPDSHDVIV FAVSSSSVAS SAALASDECS VTIGGEESDQ SSSISSGCFT SESKEIAKNS SSFGVDLEDH 101: QIETETETST FITSNFRKET SPVSEGLGET TTEMESSSAT KRKQPGVRKT PTAAEIEDLF SELESQDDKK KQFIEKYNFD IVNDEPLEGR YKWDRL |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)