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AT3G19150.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : KIP-related protein 6
Curator
Summary (TAIR10)
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility.
Computational
Description (TAIR10)
KIP-related protein 6 (KRP6); FUNCTIONS IN: cyclin binding, cyclin-dependent protein kinase inhibitor activity; INVOLVED IN: negative regulation of cyclin-dependent protein kinase activity, DNA endoreduplication; LOCATED IN: nucleus; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: D pollen mother cell meiosis stage, C tetrad of megaspores, B meiosis of megaspore mother cell; CONTAINS InterPro DOMAIN/s: Cyclin-dependent kinase inhibitor, plant (InterPro:IPR016701), Cyclin-dependent kinase inhibitor (InterPro:IPR003175); BEST Arabidopsis thaliana protein match is: Cyclin-dependent kinase inhibitor family protein (TAIR:AT1G49620.1); Has 1712 Blast hits to 484 proteins in 111 species: Archae - 0; Bacteria - 136; Metazoa - 266; Fungi - 200; Plants - 207; Viruses - 3; Other Eukaryotes - 900 (source: NCBI BLink).
Protein Annotations
BioGrid:6782DIP:DIP-38668NeggNOG:ENOG410JSMIeggNOG:ENOG41108PE
EMBL:AF106705EMBL:AF208692EMBL:AJ301557EMBL:AK229307
EMBL:AP000419EMBL:BX826140EMBL:CP002686EnsemblPlants:AT3G19150
EnsemblPlants:AT3G19150.1entrez:821449ExpressionAtlas:Q0WNX9GeneID:821449
GO:GO:0001673GO:GO:0004861GO:GO:0005654GO:GO:0007050
GO:GO:0045736hmmpanther:PTHR10265hmmpanther:PTHR10265:SF25HOGENOM:HOG000294228
InParanoid:Q0WNX9IntAct:Q0WNX9InterPro:IPR003175InterPro:IPR016701
iPTMnet:Q0WNX9KEGG:ath:AT3G19150ncoils:CoilOMA:EGRYKWD
PANTHER:PTHR10265PaxDb:Q0WNX9Pfam:PF02234Pfam:Q0WNX9
PhylomeDB:Q0WNX9PIRSF:PIRSF017811PRO:PR:Q0WNX9ProteinModelPortal:Q0WNX9
Proteomes:UP000006548RefSeq:NP_188546.1RefSeq:NP_974338.1SMR:Q0WNX9
STRING:3702.AT3G19150.1TAIR:AT3G19150tair10-symbols:ACK1tair10-symbols:ICK4
tair10-symbols:KRP6UniGene:At.8228UniProt:A6QRA0UniProt:Q0WNX9
Coordinates (TAIR10) chr3:-:6616628..6617655
Molecular Weight (calculated) 21455.20 Da
IEP (calculated) 4.24
GRAVY (calculated) -0.79
Length 196 amino acids
Sequence (TAIR10)
(BLAST)
001: MSERKRELAE EASSTSFSPL KKTKLNDSSD SSPDSHDVIV FAVSSSSVAS SAALASDECS VTIGGEESDQ SSSISSGCFT SESKEIAKNS SSFGVDLEDH
101: QIETETETST FITSNFRKET SPVSEGLGET TTEMESSSAT KRKQPGVRKT PTAAEIEDLF SELESQDDKK KQFIEKYNFD IVNDEPLEGR YKWDRL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)