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AT3G55610.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27122571 (2016): mitochondrion
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
  • PMID:20061580 (2010): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : delta 1-pyrroline-5-carboxylate synthase 2
Curator
Summary (TAIR10)
encodes delta 1-pyrroline-5-carboxylate synthetase B. Gene expression is induced by dehydration, high salt and ABA. Knock-out mutations in P5CS2 are embryo-lethal. P5CS2 appears to be present in different cells and/or different subcellular locations from P5CS1 in a tissue-dependent manner.
Computational
Description (TAIR10)
delta 1-pyrroline-5-carboxylate synthase 2 (P5CS2); FUNCTIONS IN: oxidoreductase activity, glutamate-5-semialdehyde dehydrogenase activity, catalytic activity, glutamate 5-kinase activity; INVOLVED IN: hyperosmotic salinity response, proline biosynthetic process, response to abscisic acid stimulus, embryo development ending in seed dormancy; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, C globular stage, D bilateral stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Glutamate 5-kinase (InterPro:IPR001057), Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Glutamate 5-kinase, conserved site (InterPro:IPR019797), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Gamma-glutamyl phosphate reductase GPR, conserved site (InterPro:IPR020593), Aldehyde dehydrogenase, C-terminal (InterPro:IPR016163), Delta l-pyrroline-5-carboxylate synthetase (InterPro:IPR005766), Gamma-glutamyl phosphate reductase GPR (InterPro:IPR000965), Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Glutamate 5-kinase, ProB-related (InterPro:IPR005715); BEST Arabidopsis thaliana protein match is: delta1-pyrroline-5-carboxylate synthase 1 (TAIR:AT2G39800.4); Has 14836 Blast hits to 14828 proteins in 2349 species: Archae - 139; Bacteria - 9225; Metazoa - 151; Fungi - 264; Plants - 176; Viruses - 0; Other Eukaryotes - 4881 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-931-MONOMERBioGrid:10043EC:1.2.1.41EC:2.7.2.11
eggNOG:COG0014eggNOG:COG0263eggNOG:KOG1154eggNOG:KOG4165
EMBL:AL161667EMBL:AY091766EMBL:CP002686EMBL:X86778
EMBL:Y09355EnsemblPlants:AT3G55610EnsemblPlants:AT3G55610.1entrez:824727
ExpressionAtlas:P54888Gene3D:3.40.1160.10Gene3D:3.40.309.10Gene3D:3.40.605.10
GeneID:824727Genevisible:P54888GO:GO:0004349GO:GO:0004350
GO:GO:0005524GO:GO:0005737GO:GO:0005829GO:GO:0006561
GO:GO:0009506GO:GO:0009507GO:GO:0009555GO:GO:0009793
GO:GO:0055129gramene_pathway:1.2.1.41gramene_pathway:2.7.2.11gramene_pathway:CITRULBIO-PWY
gramene_pathway:PWY-3341gramene_plant_reactome:1119495gramene_plant_reactome:6874531gramene_plant_reactome:6876564
HAMAP:MF_00412HAMAP:MF_00456hmmpanther:PTHR11063hmmpanther:PTHR11063:SF8
HOGENOM:HOG000246357InParanoid:P54888IntAct:P54888InterPro:IPR000965
InterPro:IPR001048InterPro:IPR001057InterPro:IPR005715InterPro:IPR005766
InterPro:IPR016161InterPro:IPR016162InterPro:IPR016163InterPro:IPR019797
InterPro:IPR020593iPTMnet:P54888KEGG:00330+1.2.1.41KEGG:00330+1.2.1.41+2.7.2.11
KEGG:00330+2.7.2.11KEGG:00332+1.2.1.41KEGG:00332+1.2.1.41+2.7.2.11KEGG:00332+2.7.2.11
OMA:LLPWVQSPaxDb:P54888Pfam:P54888Pfam:PF00696
PhylomeDB:P54888PIR:T47700PIR:T50682PIRSF:PIRSF036429
PRIDE:P54888PRINTS:PR00474PRO:PR:P54888PROSITE:PS00902
PROSITE:PS01223ProteinModelPortal:P54888Proteomes:UP000006548Reactome:R-ATH-70614
RefSeq:NP_191120.2scanprosite:PS00902scanprosite:PS01223SMR:P54888
STRING:3702.AT3G55610.1SUPFAM:SSF53633SUPFAM:SSF53720TAIR:AT3G55610
tair10-symbols:P5CS2TIGRfam:TIGR00407TIGRfam:TIGR01027TIGRfam:TIGR01092
TIGRFAMs:TIGR00407TIGRFAMs:TIGR01027TIGRFAMs:TIGR01092UniGene:At.25196
UniPathway:UPA00098UniProt:P54888
Coordinates (TAIR10) chr3:-:20624278..20628989
Molecular Weight (calculated) 78876.00 Da
IEP (calculated) 6.80
GRAVY (calculated) -0.09
Length 726 amino acids
Sequence (TAIR10)
(BLAST)
001: MTEIDRSRAF AKDVKRIVVK VGTAVVTGKG GRLALGRLGA ICEQLAELNS DGFEVILVSS GAVGLGRQRL RYRQLVNSSF ADLQKPQMEL DGKACAGVGQ
101: SSLMAYYETM FDQLDVTVAQ MLVTDSSFRD KDFRKQLSET VKAMLRMRVI PVFNENDAIS TRRAPYKDST GIFWDNDSLA ALLSLELKAD LLILLSDVEG
201: LYTGPPSDST SKLIHTFIKE KHQDEITFGE KSKLGRGGMT AKVKAAVNAA YGGVPVIITS GYAAENISKV LRGLRVGTLF HQDAHLWAPV VDTTSRDMAV
301: AARESSRKLQ ALSSEDRKQI LHDIANALEV NEKTIKAEND LDVAAAQEAG YEESLVARLV MKPGKISSLA ASVRQLAEME DPIGRVLKKT QVADDLILEK
401: TSSPIGVLLI VFESRPDALV QIASLAIRSG NGLLLKGGKE ARRSNAILHK VITDAIPETV GGKLIGLVTS REEIPDLLKL DDVIDLVIPR GSNKLVSQIK
501: NSTKIPVLGH ADGICHVYVD KSGKLDMAKR IVSDAKLDYP AACNAMETLL VHKDLEQNGF LDDLIYVLQT KGVTLYGGPR ASAKLNIPET KSFHHEYSSK
601: ACTVEIVEDV YGAIDHIHQH GSAHTDCIVT EDSEVAEIFL RQVDSAAVFH NASTRFSDGF RFGLGAEVGI STSRIHARGP VGVEGLLTTR WIMRGKGQVV
701: DGDNGIVYTH KDLPVLQRTE AVENGI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)