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AT2G47470.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Predictors External Curations
AmiGO : endoplasmic reticulum 16618929
AmiGO : endoplasmic reticulum 19050167
SwissProt : endoplasmic reticulum 16381842
TAIR : plasma membrane 17151019
TAIR : endoplasmic reticulum 16618929
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24970193 (2013): endoplasmic reticulum
  • PMID:19050167 (2008): endoplasmic reticulum
  • PMID:18931141 (2008): endoplasmic reticulum
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25641898 (2015): plasma membrane
  • PMID:24124904 (2013): plastid
  • PMID:24012629 (2013): nucleus
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22550958 (2012): plastid
  • PMID:22215637 (2012): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17151019 (2007): plant-type vacuole
  • PMID:16618929 (2006): endoplasmic reticulum
  • PMID:16287169 (2006): extracellular region
FP Images

Arabidopsis cell culture (peroxisomal marker)

At2g-GFP-47470
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel

onion epidermal cell layer (peroxisomal marker)

At2g-GFP-47470
(full-length)
RFP-peroxisomal markeroverlay

Images by John Bussel
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : thioredoxin family protein
Curator
Summary (TAIR10)
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.
Computational
Description (TAIR10)
UNFERTILIZED EMBRYO SAC 5 (UNE5); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: in 6 processes; LOCATED IN: endoplasmic reticulum, plasma membrane, plant-type cell wall; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Endoplasmic reticulum, protein ERp29, C-terminal (InterPro:IPR011679), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 37720 Blast hits to 19404 proteins in 2983 species: Archae - 403; Bacteria - 17657; Metazoa - 6433; Fungi - 2162; Plants - 3420; Viruses - 32; Other Eukaryotes - 7613 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G47470-MONOMERBioCyc:ARA:GQT-263-MONOMERBioCyc:ARA:GQT-264-MONOMERBioCyc:ARA:GQT-265-MONOMER
BioGrid:4695EC:5.3.4.1eggNOG:COG0526eggNOG:KOG0191
EMBL:AC002535EMBL:AF083688EMBL:AJ271470EMBL:AY074348
EMBL:AY091388EMBL:CP002685EnsemblPlants:AT2G47470EnsemblPlants:AT2G47470.1
entrez:819360ExpressionAtlas:O22263Gene3D:1.20.1150.12Gene3D:3.40.30.10
GeneID:819360Genevisible:O22263GO:GO:0003756GO:GO:0005774
GO:GO:0005783GO:GO:0006457GO:GO:0009505GO:GO:0009553
GO:GO:0009567GO:GO:0009793GO:GO:0034976GO:GO:0045454
GO:GO:0046686GO:GO:0048868hmmpanther:PTHR18929hmmpanther:PTHR18929:SF91
HOGENOM:HOG000176389InParanoid:O22263IntAct:O22263InterPro:IPR005788
InterPro:IPR011679InterPro:IPR012336InterPro:IPR013766InterPro:IPR017937
iPTMnet:O22263OMA:YKSGRDLPaxDb:O22263Pfam:O22263
Pfam:PF00085Pfam:PF07749Pfscan:PS51352PhylomeDB:O22263
PIR:T00437PRIDE:O22263PRO:PR:O22263PROSITE:PS00194
PROSITE:PS51352ProteinModelPortal:O22263Proteomes:UP000006548RefSeq:NP_182269.1
scanprosite:PS00194SMR:O22263STRING:3702.AT2G47470.1SUPFAM:SSF47933
SUPFAM:SSF52833SWISS-2DPAGE:O22263SwissPalm:O22263TAIR:AT2G47470
tair10-symbols:ATPDI11tair10-symbols:ATPDIL2-1tair10-symbols:MEE30tair10-symbols:PDI11
tair10-symbols:UNE5TIGRfam:TIGR01126TIGRFAMs:TIGR01126TMHMM:TMhelix
UniGene:At.24396UniGene:At.66351UniProt:O22263
Coordinates (TAIR10) chr2:+:19481503..19483683
Molecular Weight (calculated) 39498.90 Da
IEP (calculated) 5.86
GRAVY (calculated) -0.29
Length 361 amino acids
Sequence (TAIR10)
(BLAST)
001: MAKSQIWFGF ALLALLLVSA VADDVVVLTD DSFEKEVGKD KGALVEFYAP WCGHCKKLAP EYEKLGASFK KAKSVLIAKV DCDEQKSVCT KYGVSGYPTI
101: QWFPKGSLEP QKYEGPRNAE ALAEYVNKEG GTNVKLAAVP QNVVVLTPDN FDEIVLDQNK DVLVEFYAPW CGHCKSLAPT YEKVATVFKQ EEGVVIANLD
201: ADAHKALGEK YGVSGFPTLK FFPKDNKAGH DYDGGRDLDD FVSFINEKSG TSRDSKGQLT SKAGIVESLD ALVKELVAAS EDEKKAVLSR IEEEASTLKG
301: STTRYGKLYL KLAKSYIEKG SDYASKETER LGRVLGKSIS PVKADELTLK RNILTTFVAS S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)