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AT1G04980.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:24970193 (2013): endoplasmic reticulum
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:16287169 (2006): extracellular region
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : PDI-like 2-2
Curator
Summary (TAIR10)
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.
Computational
Description (TAIR10)
PDI-like 2-2 (PDIL2-2); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-3 (TAIR:AT2G32920.1); Has 36254 Blast hits to 18629 proteins in 2906 species: Archae - 392; Bacteria - 18066; Metazoa - 5792; Fungi - 2053; Plants - 2624; Viruses - 46; Other Eukaryotes - 7281 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G04980-MONOMEREC:5.3.4.1eggNOG:COG0526eggNOG:KOG0191
EMBL:AC004809EMBL:AY099813EMBL:CP002684EnsemblPlants:AT1G04980
EnsemblPlants:AT1G04980.1entrez:839355Gene3D:3.40.30.10GeneID:839355
Genevisible:Q9MAU6GO:GO:0003756GO:GO:0005783GO:GO:0005788
GO:GO:0006457GO:GO:0009505GO:GO:0034976GO:GO:0045454
Gramene:AT1G04980.1hmmpanther:PTHR18929hmmpanther:PTHR18929:SF38HOGENOM:HOG000012631
InParanoid:Q9MAU6InterPro:IPR005788InterPro:IPR012336InterPro:IPR013766
InterPro:IPR017937KEGG:ath:AT1G04980KO:K09584OMA:KNLEPEW
PaxDb:Q9MAU6Pfam:PF00085Pfam:Q9MAU6Pfscan:PS51352
PhylomeDB:Q9MAU6PIR:D86183PRIDE:Q9MAU6PRO:PR:Q9MAU6
PROSITE:PS00194PROSITE:PS51352ProteinModelPortal:Q9MAU6Proteomes:UP000006548
RefSeq:NP_171990.3scanprosite:PS00194SMR:Q9MAU6STRING:3702.AT1G04980.1
SUPFAM:SSF52833TAIR:AT1G04980tair10-symbols:ATPDI10tair10-symbols:ATPDIL2-2
tair10-symbols:PDI10tair10-symbols:PDIL2-2TIGRfam:TIGR01126TIGRFAMs:TIGR01126
UniGene:At.12010UniProt:Q9MAU6
Coordinates (TAIR10) chr1:-:1413869..1416120
Molecular Weight (calculated) 48405.60 Da
IEP (calculated) 6.39
GRAVY (calculated) -0.29
Length 447 amino acids
Sequence (TAIR10)
(BLAST)
001: MERKMYKSTV FPICCLLFAL FDRGNALYGS SSPVLQLTPS NFKSKVLNSN GVVLVEFFAP WCGHCQSLTP TWEKVASTLK GIATVAAIDA DAHKSVSQDY
101: GVRGFPTIKV FVPGKPPIDY QGARDAKSIS QFAIKQIKAL LKDRLDGKTS GTKNGGGSSE KKKSEPSASV ELNSSNFDEL VTESKELWIV EFFAPWCGHC
201: KKLAPEWKKA ANNLKGKVKL GHVNCDAEQS IKSRFKVQGF PTILVFGSDK SSPVPYEGAR SASAIESFAL EQLESNAGPA EVTELTGPDV MEDKCGSAAI
301: CFVSFLPDIL DSKAEGRNKY LEMLLSVADK FKKDPYGFVW VAAGKQPDLE KRVGVGGYGY PAMVALNAKK GAYAPLKSGF EVKHLKDFVK EAAKGGKGNL
401: PIDGTMEIVK TEAWDGKDGE VVDADEFSLE DLMGNDDEAS TESKDDL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)