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AT2G22490.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Cyclin D2;1
Curator
Summary (TAIR10)
encodes a D-type cyclin whose transcription level is regulated by sucrose but not phytohormones or nitrate. Protein physically interacts with CDC2A. CycD2 kinase activity is regulated by sequestration of CycD2 protein in a form inaccessible to immunoprecipitation and probably not complexed to CDC2A.
Computational
Description (TAIR10)
Cyclin D2;1 (CYCD2;1); FUNCTIONS IN: protein binding, cyclin-dependent protein kinase regulator activity; INVOLVED IN: G1 phase of mitotic cell cycle, regulation of cell cycle, response to sucrose stimulus; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin D (InterPro:IPR015451), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: CYCLIN D4;1 (TAIR:AT5G65420.1); Has 3365 Blast hits to 3363 proteins in 312 species: Archae - 0; Bacteria - 0; Metazoa - 1602; Fungi - 305; Plants - 1074; Viruses - 0; Other Eukaryotes - 384 (source: NCBI BLink).
Protein Annotations
BioGrid:2135eggNOG:ENOG410XRKCeggNOG:KOG0656EMBL:AC006592
EMBL:AK228250EMBL:BT025242EMBL:CP002685EMBL:X83370
EnsemblPlants:AT2G22490EnsemblPlants:AT2G22490.1entrez:816782ExpressionAtlas:P42752
Gene3D:1.10.472.10GeneID:816782Genevisible:P42752GO:GO:0005634
GO:GO:0007049GO:GO:0051301hmmpanther:PTHR10177hmmpanther:PTHR10177:SF234
HOGENOM:HOG000242458InParanoid:P42752IntAct:P42752InterPro:IPR004367
InterPro:IPR006671InterPro:IPR013763PaxDb:P42752Pfam:P42752
Pfam:PF00134Pfam:PF02984PhylomeDB:P42752PIR:C84613
PRIDE:P42752PRO:PR:P42752PROSITE:PS00292ProteinModelPortal:P42752
Proteomes:UP000006548RefSeq:NP_179835.1scanprosite:PS00292SMART:SM00385
SMART:SM01332SMR:P42752STRING:3702.AT2G22490.2SUPFAM:SSF47954
TAIR:AT2G22490tair10-symbols:ATCYCD2;1tair10-symbols:CYCD2;1UniGene:At.9
UniProt:P42752
Coordinates (TAIR10) chr2:-:9554157..9555873
Molecular Weight (calculated) 40581.90 Da
IEP (calculated) 4.70
GRAVY (calculated) -0.32
Length 361 amino acids
Sequence (TAIR10)
(BLAST)
001: MAENLACGET SESWIIDNDD DDINYGGGFT NEIDYNHQLF AKDDNFGGNG SIPMMGSSSS SLSEDRIKEM LVREIEFCPG TDYVKRLLSG DLDLSVRNQA
101: LDWILKVCAH YHFGHLCICL SMNYLDRFLT SYELPKDKDW AAQLLAVSCL SLASKMEETD VPHIVDLQVE DPKFVFEAKT IKRMELLVVT TLNWRLQALT
201: PFSFIDYFVD KISGHVSENL IYRSSRFILN TTKAIEFLDF RPSEIAAAAA VSVSISGETE CIDEEKALSS LIYVKQERVK RCLNLMRSLT GEENVRGTSL
301: SQEQARVAVR AVPASPVGVL EATCLSYRSE ERTVESCTNS SQSSPDNNNN NNNSNKRRRK Q
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)