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AT3G44310.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31541795 (2020): plasma membrane
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31186290 (2019): plastid plastid stroma
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:27122571 (2016): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25641898 (2015): plasma membrane
  • PMID:25587034 (2015): cytosol
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22550958 (2012): plastid
  • PMID:22215637 (2012): plasma membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
  • PMID:20423899 (2010): plastid
  • PMID:19334764 (2009): plasma membrane
  • PMID:18431481 (2008): plastid
  • PMID:17317660 (2007): plasma membrane
  • PMID:15574830 (2004): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : nitrilase 1
Curator
Summary (TAIR10)
Mutants are resistant to indole-3-acetonitrile (IAN). NIT1 catalyzes the terminal activation step in indole-acetic acid biosynthesis. Predominantly expressed isoform of nitrilase isoenzyme family. Aggregation of NIT1 in cells directly abutting wound sites is one of the earliest events associated with wound and herbicide-induced cell death. The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide. It is also involved in the conversion of IAN to IAM (indole-3-acetamide) and other non-auxin-related metabolic processes.
Computational
Description (TAIR10)
nitrilase 1 (NIT1); FUNCTIONS IN: indole-3-acetonitrile nitrilase activity, nitrilase activity, indole-3-acetonitrile nitrile hydratase activity; INVOLVED IN: indoleacetic acid biosynthetic process; LOCATED IN: apoplast, chloroplast, plasma membrane; EXPRESSED IN: guard cell, cultured cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (InterPro:IPR003010), Nitrilase/cyanide hydratase, conserved site (InterPro:IPR000132); BEST Arabidopsis thaliana protein match is: nitrilase 2 (TAIR:AT3G44300.1); Has 7572 Blast hits to 7496 proteins in 1731 species: Archae - 139; Bacteria - 4902; Metazoa - 443; Fungi - 562; Plants - 319; Viruses - 11; Other Eukaryotes - 1196 (source: NCBI BLink).
Protein Annotations
BioGrid:8876eggNOG:COG0388eggNOG:KOG0805EMBL:AB493638
EnsemblPlants:AT3G44310EnsemblPlants:AT3G44310.1EnsemblPlants:AT3G44310.3entrez:823556
ExpressionAtlas:C0SVD5Gene3D:3.60.110.10GeneID:823556GO:GO:0006807
GO:GO:0016810Gramene:AT3G44310.1Gramene:AT3G44310.3gramene_plant_reactome:1119486
gramene_plant_reactome:6876740hmmpanther:PTHR23088hmmpanther:PTHR23088:SF31InterPro:IPR000132
InterPro:IPR003010iPTMnet:C0SVD5KEGG:ath:AT3G44310KO:K01501
OMA:HATEIWVPaxDb:C0SVD5Pfam:P32961Pfam:PF00795
Pfscan:PS50263PhylomeDB:C0SVD5PRIDE:C0SVD5PROSITE:PS00920
PROSITE:PS00921PROSITE:PS50263ProteinModelPortal:C0SVD5RefSeq:NP_001078234.1
RefSeq:NP_851011.1scanprosite:PS00920scanprosite:PS00921SMR:C0SVD5
STRING:3702.AT3G44310.1SUPFAM:SSF56317TAIR:AT3G44310tair10-symbols:ATNIT1
tair10-symbols:NIT1tair10-symbols:NITIUniGene:At.23699UniGene:At.23715
UniGene:At.5403UniGene:At.5404UniProt:C0SVD5UniProt:P32961
Coordinates (TAIR10) chr3:+:15986901..15988841
Molecular Weight (calculated) 38154.20 Da
IEP (calculated) 6.23
GRAVY (calculated) -0.23
Length 346 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSTKDMSTV QNATPFNGVA PSTTVRVTIV QSSTVYNDTP ATIDKAEKYI VEAASKGAEL VLFPEGFIGG YPRGFRFGLA VGVHNEEGRD EFRKYHASAI
101: HVPGPEVARL ADVARKNHVY LVMGAIEKEG YTLYCTVLFF SPQGQFLGKH RKLMPTSLER CIWGQGDGST IPVYDTPIGK LGAAICWENR MPLYRTALYA
201: KGIELYCAPT ADGSKEWQSS MLHIAIEGGC FVLSACQFCQ RKHFPDHPDY LFTDWYDDKE HDSIVSQGGS VIISPLGQVL AGPNFESEGL VTADIDLGDI
301: ARAKLYFDSV GHYSRPDVLH LTVNEHPRKS VTFVTKVEKA EDDSNK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)