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AT2G40890.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
endoplasmic reticulum 1.000
What is SUBAcon?
Predictors External Curations
AmiGO : endoplasmic reticulum 16618929
SwissProt : plasma membrane 16381842
TAIR : plasma membrane 17317660
TAIR : mitochondrion 15276431
TAIR : endoplasmic reticulum 16618929
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:23175744 (2012): endoplasmic reticulum endoplasmic reticulum membrane
  • PMID:21515817 (2011): endoplasmic reticulum
  • PMID:31818904 (2020): mitochondrion
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23323832 (2013): plasma membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22215637 (2012): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:16618929 (2006): endoplasmic reticulum
  • PMID:15276431 (2004): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cytochrome P450, family 98, subfamily A, polypeptide 3
Curator
Summary (TAIR10)
encodes coumarate 3-hydroxylase (C3H), a P450-dependent monooxygenase. Involved in lignin biosynthesis and flavonoid biosynthesis. Also affects the biosynthesis of coumarins such as scopoletin and scopolin as a branching-out-pathway from the phenylpropanoid acid level.
Computational
Description (TAIR10)
cytochrome P450, family 98, subfamily A, polypeptide 3 (CYP98A3); FUNCTIONS IN: monooxygenase activity, p-coumarate 3-hydroxylase activity; INVOLVED IN: coumarin biosynthetic process, lignin biosynthetic process, phenylpropanoid biosynthetic process, flavonoid biosynthetic process; LOCATED IN: mitochondrion, endoplasmic reticulum, plasma membrane, microsome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 98, subfamily A, polypeptide 9 (TAIR:AT1G74550.1); Has 33899 Blast hits to 33682 proteins in 1752 species: Archae - 48; Bacteria - 3997; Metazoa - 11870; Fungi - 7164; Plants - 9566; Viruses - 3; Other Eukaryotes - 1251 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:AT2G40890-MONOMERBioGrid:4023EC:1.14.-.-eggNOG:COG2124
eggNOG:KOG0156EMBL:AC002409EMBL:AK226377EMBL:AY056105
EMBL:CP002685EnsemblPlants:AT2G40890EnsemblPlants:AT2G40890.1entrez:818686
Gene3D:1.10.630.10GeneID:818686Genevisible:O22203GO:GO:0004497
GO:GO:0005506GO:GO:0005739GO:GO:0005783GO:GO:0005886
GO:GO:0009699GO:GO:0009805GO:GO:0009809GO:GO:0009813
GO:GO:0016021GO:GO:0016709GO:GO:0020037GO:GO:0042802
GO:GO:0043231GO:GO:0046409Gramene:AT2G40890.1gramene_pathway:1.14.13.36
gramene_pathway:PWY-1121gramene_pathway:PWY-2181gramene_pathway:PWY-361gramene_pathway:PWY-5868
gramene_plant_reactome:1119316gramene_plant_reactome:6874683gramene_plant_reactome:6875203hmmpanther:PTHR24298
hmmpanther:PTHR24298:SF0HOGENOM:HOG000218628InParanoid:O22203InterPro:IPR001128
InterPro:IPR002401InterPro:IPR017972iPTMnet:O22203KEGG:ath:AT2G40890
KO:K09754OMA:CTNPENNPaxDb:O22203Pfam:O22203
Pfam:PF00067PhylomeDB:O22203PIR:T00753PRIDE:O22203
PRINTS:PR00385PRINTS:PR00463PRO:PR:O22203PROSITE:PS00086
ProteinModelPortal:O22203Proteomes:UP000006548RefSeq:NP_850337.1SABIO-RK:O22203
scanprosite:PS00086SMR:O22203STRING:3702.AT2G40890.1SUPFAM:SSF48264
TAIR:AT2G40890tair10-symbols:CYP98A3UniGene:At.19895UniGene:At.24415
UniProt:O22203
Coordinates (TAIR10) chr2:-:17058291..17060532
Molecular Weight (calculated) 57930.10 Da
IEP (calculated) 8.82
GRAVY (calculated) -0.26
Length 508 amino acids
Sequence (TAIR10)
(BLAST)
001: MSWFLIAVAT IAAVVSYKLI QRLRYKFPPG PSPKPIVGNL YDIKPVRFRC YYEWAQSYGP IISVWIGSIL NVVVSSAELA KEVLKEHDQK LADRHRNRST
101: EAFSRNGQDL IWADYGPHYV KVRKVCTLEL FTPKRLESLR PIREDEVTAM VESVFRDCNL PENRAKGLQL RKYLGAVAFN NITRLAFGKR FMNAEGVVDE
201: QGLEFKAIVS NGLKLGASLS IAEHIPWLRW MFPADEKAFA EHGARRDRLT RAIMEEHTLA RQKSSGAKQH FVDALLTLKD QYDLSEDTII GLLWDMITAG
301: MDTTAITAEW AMAEMIKNPR VQQKVQEEFD RVVGLDRILT EADFSRLPYL QCVVKESFRL HPPTPLMLPH RSNADVKIGG YDIPKGSNVH VNVWAVARDP
401: AVWKNPFEFR PERFLEEDVD MKGHDFRLLP FGAGRRVCPG AQLGINLVTS MMSHLLHHFV WTPPQGTKPE EIDMSENPGL VTYMRTPVQA VATPRLPSDL
501: YKRVPYDM
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)