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AT1G51680.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27943495 (2017): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 4-coumarate:CoA ligase 1
Curator
Summary (TAIR10)
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.
Computational
Description (TAIR10)
4-coumarate:CoA ligase 1 (4CL1); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 83980 Blast hits to 76655 proteins in 3756 species: Archae - 1185; Bacteria - 53552; Metazoa - 3476; Fungi - 4550; Plants - 2810; Viruses - 1; Other Eukaryotes - 18406 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G51680-MONOMERBioCyc:ARA:GQT-1620-MONOMERBioCyc:ARA:GQT-1621-MONOMERBioCyc:MetaCyc:AT1G51680-MONOMER
BRENDA:6.2.1.12EC:6.2.1.12eggNOG:COG0318eggNOG:KOG1176
EMBL:AC025294EMBL:AF106084EMBL:AY075622EMBL:AY099747
EMBL:AY133582EMBL:AY376729EMBL:CP002684EMBL:U18675
EnsemblPlants:AT1G51680EnsemblPlants:AT1G51680.1entrez:841593ExpressionAtlas:Q42524
GeneID:841593Genevisible:Q42524GO:GO:0005524GO:GO:0005737
GO:GO:0009698GO:GO:0016207gramene_pathway:6.2.1.12gramene_pathway:6.2.1.34
gramene_pathway:PWY-1121gramene_pathway:PWY-361gramene_pathway:PWY-5868gramene_pathway:PWY1F-FLAVSYN
gramene_pathway:PWY4FS-9hmmpanther:PTHR24096hmmpanther:PTHR24096:SF149HOGENOM:HOG000230009
InParanoid:Q42524InterPro:IPR000873InterPro:IPR020845InterPro:IPR025110
OMA:KESTDACPaxDb:Q42524PDB:3TSYPDBsum:3TSY
Pfam:PF00501Pfam:PF13193Pfam:Q42524PhylomeDB:Q42524
PIR:S57784PRIDE:Q42524PRO:PR:Q42524PROSITE:PS00455
ProteinModelPortal:Q42524Proteomes:UP000006548Reactome:R-ATH-75105RefSeq:NP_175579.1
RefSeq:NP_849793.1SABIO-RK:Q42524scanprosite:PS00455SMR:Q42524
STRING:3702.AT1G51680.1SUPFAM:SSF56801TAIR:AT1G51680tair10-symbols:4CL.1
tair10-symbols:4CL1tair10-symbols:AT4CL1TCDB:4.C.1.1.7UniGene:At.21694
UniPathway:UPA00372UniProt:Q42524
Coordinates (TAIR10) chr1:-:19159007..19161464
Molecular Weight (calculated) 61056.70 Da
IEP (calculated) 5.08
GRAVY (calculated) 0.02
Length 561 amino acids
Sequence (TAIR10)
(BLAST)
001: MAPQEQAVSQ VMEKQSNNNN SDVIFRSKLP DIYIPNHLSL HDYIFQNISE FATKPCLING PTGHVYTYSD VHVISRQIAA NFHKLGVNQN DVVMLLLPNC
101: PEFVLSFLAA SFRGATATAA NPFFTPAEIA KQAKASNTKL IITEARYVDK IKPLQNDDGV VIVCIDDNES VPIPEGCLRF TELTQSTTEA SEVIDSVEIS
201: PDDVVALPYS SGTTGLPKGV MLTHKGLVTS VAQQVDGENP NLYFHSDDVI LCVLPMFHIY ALNSIMLCGL RVGAAILIMP KFEINLLLEL IQRCKVTVAP
301: MVPPIVLAIA KSSETEKYDL SSIRVVKSGA APLGKELEDA VNAKFPNAKL GQGYGMTEAG PVLAMSLGFA KEPFPVKSGA CGTVVRNAEM KIVDPDTGDS
401: LSRNQPGEIC IRGHQIMKGY LNNPAATAET IDKDGWLHTG DIGLIDDDDE LFIVDRLKEL IKYKGFQVAP AELEALLIGH PDITDVAVVA MKEEAAGEVP
501: VAFVVKSKDS ELSEDDVKQF VSKQVVFYKR INKVFFTESI PKAPSGKILR KDLRAKLANG L
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)