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AT3G21240.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : 4-coumarate:CoA ligase 2
Curator
Summary (TAIR10)
encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.
Computational
Description (TAIR10)
4-coumarate:CoA ligase 2 (4CL2); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 1 (TAIR:AT1G51680.1); Has 86092 Blast hits to 78635 proteins in 3758 species: Archae - 1209; Bacteria - 54193; Metazoa - 3597; Fungi - 4717; Plants - 2816; Viruses - 1; Other Eukaryotes - 19559 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G21240-MONOMERBioCyc:MetaCyc:AT3G21240-MONOMERBRENDA:6.2.1.12EC:6.2.1.12
eggNOG:COG0318eggNOG:KOG1176EMBL:AB023045EMBL:AF106085
EMBL:AF106086EMBL:AK220883EMBL:AY099695EMBL:AY376728
EMBL:BT000296EMBL:CP002686EnsemblPlants:AT3G21240EnsemblPlants:AT3G21240.1
entrez:821678ExpressionAtlas:Q9S725GeneID:821678Genevisible:Q9S725
GO:GO:0005524GO:GO:0009698GO:GO:0016207Gramene:AT3G21240.1
gramene_pathway:6.2.1.12gramene_pathway:PWY-1121gramene_pathway:PWY-361gramene_pathway:PWY-5868
gramene_pathway:PWY1F-FLAVSYNgramene_pathway:PWY4FS-9hmmpanther:PTHR24096hmmpanther:PTHR24096:SF149
HOGENOM:HOG000230009InParanoid:Q9S725InterPro:IPR000873InterPro:IPR020845
InterPro:IPR025110iPTMnet:Q9S725KEGG:ath:AT3G21240KO:K01904
OMA:IMRAPQLPaxDb:Q9S725Pfam:PF00501Pfam:PF13193
Pfam:Q9S725PhylomeDB:Q9S725PRIDE:Q9S725PRO:PR:Q9S725
PROSITE:PS00455ProteinModelPortal:Q9S725Proteomes:UP000006548Reactome:R-ATH-75105
RefSeq:NP_188761.1SABIO-RK:Q9S725scanprosite:PS00455SMR:Q9S725
STRING:3702.AT3G21240.1SUPFAM:SSF56801TAIR:AT3G21240tair10-symbols:4CL2
tair10-symbols:AT4CL2UniGene:At.57587UniPathway:UPA00372UniProt:B1GUZ3
UniProt:Q9S725
Coordinates (TAIR10) chr3:-:7454497..7457314
Molecular Weight (calculated) 60845.70 Da
IEP (calculated) 5.28
GRAVY (calculated) -0.01
Length 556 amino acids
Sequence (TAIR10)
(BLAST)
001: MTTQDVIVND QNDQKQCSND VIFRSRLPDI YIPNHLPLHD YIFENISEFA AKPCLINGPT GEVYTYADVH VTSRKLAAGL HNLGVKQHDV VMILLPNSPE
101: VVLTFLAASF IGAITTSANP FFTPAEISKQ AKASAAKLIV TQSRYVDKIK NLQNDGVLIV TTDSDAIPEN CLRFSELTQS EEPRVDSIPE KISPEDVVAL
201: PFSSGTTGLP KGVMLTHKGL VTSVAQQVDG ENPNLYFNRD DVILCVLPMF HIYALNSIML CSLRVGATIL IMPKFEITLL LEQIQRCKVT VAMVVPPIVL
301: AIAKSPETEK YDLSSVRMVK SGAAPLGKEL EDAISAKFPN AKLGQGYGMT EAGPVLAMSL GFAKEPFPVK SGACGTVVRN AEMKILDPDT GDSLPRNKPG
401: EICIRGNQIM KGYLNDPLAT ASTIDKDGWL HTGDVGFIDD DDELFIVDRL KELIKYKGFQ VAPAELESLL IGHPEINDVA VVAMKEEDAG EVPVAFVVRS
501: KDSNISEDEI KQFVSKQVVF YKRINKVFFT DSIPKAPSGK ILRKDLRARL ANGLMN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)