AT2G20990.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:endoplasmic reticulum 0.973 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : synaptotagmin A | ||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a plasma membrane localized protein with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance. SYT1 probably plays a role in membrane repair such as membrane resealing after freezing induced damage. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway. | ||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
synaptotagmin A (SYTA); CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 region (InterPro:IPR020477), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT1G20080.1). | ||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:9014827..9017829 | ||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 66263.90 Da | ||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.94 | ||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.24 | ||||||||||||||||||||||||||||||||||||
| Length | 579 amino acids | ||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGFFSTILGF CGFGVGISLG LVIGYVLFVY LLPNDVKDPE IRSIADQDPK AMLRMLPEIP LWVKNPDFDR VDWINRFLEY MWPYLDKAIC KTAKNIAKPI 101: IEEQIPKYKI DSVEFETLTL GSLPPTFQGM KVYLTDEKEL IMEPCLKWAA NPNILVAIKA FGLKATVQVV DLQVFAQPRI TLKPLVPSFP CFANIYVSLM 201: EKPHVDFGLK LGGADLMSIP GLYRFVQVDI FLLHTSFKSL TCMSKNFFMR ERADETVTFR LANTYEQIKD QVANMYLWPK TLVVPILDPA KAFRRPVGIV 301: HVKVVRAVGL RKKDLMGGAD PFVKIKLSED KIPSKKTTVK HKNLNPEWNE EFKFSVRDPQ TQVLEFSVYD WEQVGNPEKM GMNVLALKEM VPDEHKAFTL 401: ELRKTLDGGE DGQPPDKYRG KLEVELLYKP FTEEEMPKGF EETQAVQKAP EGTPAAGGML VVIVHSAEDV EGKHHTNPYV RIYFKGEERK TKHVKKNRDP 501: RWNEEFTFML EEPPVREKLH VEVLSTSSRI GLLHPKETLG YVDIPVVDVV NNKRMNQKFH LIDSKNGKIQ IELEWRTAS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)