AT2G45140.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:endoplasmic reticulum 1.000 ASURE: endoplasmic reticulum What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : plant VAP homolog 12 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a Plant VAMP-Associated protein that localizes to the ER and binds to the sitosterol-binding protein ORP3a. The WFDE motif in ORP3a appears to be important for this direct interaction. Mutation of this motif causes ORP3a to relocalize to the Golgi and cytosol. The interaction between PVA12 and ORP3a does not appear to be sterol-dependent. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
plant VAP homolog 12 (PVA12); FUNCTIONS IN: structural molecule activity; LOCATED IN: cytosol, endoplasmic reticulum, nucleus, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: PapD-like (InterPro:IPR008962), Major sperm protein (InterPro:IPR000535), Vesicle-associated membrane protein (InterPro:IPR016763); BEST Arabidopsis thaliana protein match is: vesicle associated protein (TAIR:AT3G60600.1); Has 1106 Blast hits to 1079 proteins in 208 species: Archae - 0; Bacteria - 0; Metazoa - 441; Fungi - 140; Plants - 434; Viruses - 0; Other Eukaryotes - 91 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:18611029..18612971 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 26443.60 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 9.14 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.47 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 239 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MSNELLTIDP VDLQFPFELK KQISCSLYLG NKTDNYVAFK VKTTNPKKYC VRPNTGVVHP RSSSEVLVTM QAQKEAPADL QCKDKFLLQC VVASPGATPK 101: DVTHEMFSKE AGHRVEETKL RVVYVAPPRP PSPVREGSEE GSSPRASVSD NGNASDFTAA PRFSADRVDA QDNSSEARAL VTKLTEEKNS AVQLNNRLQQ 201: ELDQLRRESK RSKSGGIPFM YVLLVGLIGL ILGYIMKRT |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)