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AT2G04660.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.998
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : anaphase-promoting complex/cyclosome 2
Curator
Summary (TAIR10)
a highly conserved ubiquitin-protein ligase involved in cell cycle regulation
Computational
Description (TAIR10)
anaphase-promoting complex/cyclosome 2 (APC2); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin protein ligase binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Cullin homology (InterPro:IPR016158), Anaphase promoting complex subunit 2 (InterPro:IPR014786), Cullin, N-terminal (InterPro:IPR001373); BEST Arabidopsis thaliana protein match is: cullin4 (TAIR:AT5G46210.1); Has 1400 Blast hits to 1393 proteins in 217 species: Archae - 0; Bacteria - 0; Metazoa - 534; Fungi - 454; Plants - 255; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink).
Protein Annotations
BioGrid:409eggNOG:ENOG410XRBYeggNOG:KOG2165EMBL:AC006955
EMBL:AK118453EMBL:AY138228EMBL:CP002685EnsemblPlants:AT2G04660
EnsemblPlants:AT2G04660.1entrez:815008Gene3D:1.10.10.10GeneID:815008
Genevisible:Q8H1U5GO:GO:0005634GO:GO:0005680GO:GO:0005819
GO:GO:0007067GO:GO:0009561GO:GO:0031625GO:GO:0042787
GO:GO:0051301Gramene:AT2G04660.1hmmpanther:PTHR11932hmmpanther:PTHR11932:SF5
HOGENOM:HOG000265303InParanoid:Q8H1U5IntAct:Q8H1U5InterPro:IPR001373
InterPro:IPR011991InterPro:IPR014786InterPro:IPR016158KEGG:ath:AT2G04660
KO:K03349OMA:NRRISFWPaxDb:Q8H1U5Pfam:PF00888
Pfam:PF08672Pfam:Q8H1U5Pfscan:PS50069PhylomeDB:Q8H1U5
PIR:H84459PRIDE:Q8H1U5PRO:PR:Q8H1U5PROSITE:PS50069
ProteinModelPortal:Q8H1U5Proteomes:UP000006548Reactome:R-ATH-174184Reactome:R-ATH-179409
RefSeq:NP_178543.2SMART:SM00182SMART:SM01013SMR:Q8H1U5
STRING:3702.AT2G04660.1SUPFAM:SSF46785SUPFAM:SSF75632TAIR:AT2G04660
tair10-symbols:APC2UniGene:At.41283UniPathway:UPA00143UniProt:Q8H1U5
Coordinates (TAIR10) chr2:+:1624933..1629039
Molecular Weight (calculated) 97795.90 Da
IEP (calculated) 4.53
GRAVY (calculated) -0.34
Length 865 amino acids
Sequence (TAIR10)
(BLAST)
001: MEALGSSDCN LEILETLSDD AIQEITESYD GFFTTVESLI AGTGDSLVED EFVSHVYCLC KYGLDSLVRD HFLRSLEQAF EKGGASSFWQ HFDAYSEKKH
101: HNYGEEIQIV LCKALEEISI EKQYHEKCLS IVVHALQSFK EQSSDDRQNS DTERVHLFSR FQSMLSSTLM TTLPQHFPEI LHWYFKERLE ELSAIMDGDG
201: IEEQEDDCMD LDEKLRYKNG EMDVDEGCSQ GKRLGHDKLV KNIGKVVRDL RSIGFTSMAE NAYASAIFLL LKAKVHDLAG DDYRTSVLES IKEWIQTVPL
301: QFLNALLSYL GDSVSYGTTS SGLTSPLACC PSPSFSRVVT PSEGIVRWKL RLEYFAYETL QDLRIAKLFE IIVDYPESSP AIEDLKQCLE YTGQHSKLVE
401: SFISSLKYRL LTAGASTNDI LHQYVSTIKA LRAIDPAGVF LEAVGEPIRD YLRGRKDTIK CIVTMLTDGS GGNANGSGNP GDSLLEELMR DEESQENVGF
501: DDDFHTDDKQ AWINASRWEP DPVEADPLKG SLSQRKVDIL GMLVDIIGSK EQLVNEYRVM LAEKLLNKTD YDIDTEIRTV ELLKIHFGEA SMQRCEIMLN
601: DLIDSKRVNT NIKKASQTGA ELRENELSVD TLTSTILSTN FWPPIQDEPL ELPGPVDKLL SDYANRYHEI KTPRKLLWKK NLGTVKLELQ FEDRAMQFTV
701: SPTHAAIIMQ FQEKKSWTYK DLAEVIGIPI DALNRRVNFW ISKGVLREST GANSNSSVLT LVESITDSGK NEGEELLTGE EEGETSIASV EDQLRKEMTI
801: YEKFIMGMLT NFGSMALERI HNTLKMFCVA DPSYDKSLQQ LQSFLSGLVS EEKLEFRDGM YLLKK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)