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AT3G54470.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.999
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:22550958 (2012): plastid
  • PMID:21166475 (2011): cytosol
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS)
Curator
Summary (TAIR10)
encodes the bi-functional orotate phosphoribosyltransferase/orotidine-5'-phosphate decarboxylase catalyzing the fifth and sixth step in the de novo pyrimidine ribonucleotide biosynthesis
Computational
Description (TAIR10)
uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS); FUNCTIONS IN: orotate phosphoribosyltransferase activity, orotidine-5'-phosphate decarboxylase activity; INVOLVED IN: response to cadmium ion, cellular response to phosphate starvation, pyrimidine ribonucleotide biosynthetic process, nucleoside metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: guard cell, cultured cell; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Orotidine 5'-phosphate decarboxylase, subfamily 1, core (InterPro:IPR014732), Orotidine 5'-phosphate decarboxylase, active site (InterPro:IPR018089), Ribulose-phosphate binding barrel (InterPro:IPR011060), Phosphoribosyltransferase (InterPro:IPR000836), Orotate phosphoribosyl transferase (InterPro:IPR004467), Orotidine 5'-phosphate decarboxylase, core (InterPro:IPR001754); Has 9174 Blast hits to 9124 proteins in 2964 species: Archae - 386; Bacteria - 5538; Metazoa - 208; Fungi - 955; Plants - 89; Viruses - 3; Other Eukaryotes - 1995 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G54470-MONOMERBioCyc:MetaCyc:AT3G54470-MONOMERBioGrid:9928EC:2.4.2.10
EC:4.1.1.23eggNOG:COG0284eggNOG:COG0461eggNOG:KOG1377
EMBL:AF276887EMBL:AL138656EMBL:AY140098EMBL:BT006612
EMBL:CP002686EMBL:X71842EnsemblPlants:AT3G54470EnsemblPlants:AT3G54470.1
entrez:824612Gene3D:3.20.20.70Gene3D:3.40.50.2020GeneID:824612
GO:GO:0004588GO:GO:0004590GO:GO:0005829GO:GO:0006207
GO:GO:0016036GO:GO:0044205GO:GO:0046686Gramene:AT3G54470.1
gramene_pathway:2.4.2.10gramene_pathway:4.1.1.23gramene_pathway:PWY-5686HAMAP:MF_01208
HOGENOM:HOG000213905InterPro:IPR000836InterPro:IPR001754InterPro:IPR004467
InterPro:IPR011060InterPro:IPR013785InterPro:IPR014732InterPro:IPR018089
InterPro:IPR023031InterPro:IPR029057KEGG:00240+2.4.2.10KEGG:00240+4.1.1.23
KEGG:00983+2.4.2.10KEGG:ath:AT3G54470KO:K13421OMA:SMKPEFL
PaxDb:Q42586Pfam:PF00156Pfam:PF00215Pfam:Q42586
PhylomeDB:Q42586PIR:S46440PIR:T47606PRIDE:Q42586
PRO:PR:Q42586PROSITE:PS00103PROSITE:PS00156ProteinModelPortal:Q42586
Proteomes:UP000006548Reactome:R-ATH-500753RefSeq:NP_680130.1scanprosite:PS00156
SMART:SM00934SMR:Q42586STRING:3702.AT3G54470.1SUPFAM:SSF51366
SUPFAM:SSF53271TAIR:AT3G54470TIGRfam:TIGR00336TIGRfam:TIGR01740
TIGRFAMs:TIGR00336TIGRFAMs:TIGR01740UniGene:At.108UniPathway:UPA00070
UniProt:Q42586
Coordinates (TAIR10) chr3:-:20168285..20170245
Molecular Weight (calculated) 51853.50 Da
IEP (calculated) 7.25
GRAVY (calculated) 0.07
Length 476 amino acids
Sequence (TAIR10)
(BLAST)
001: MSAMEALILQ LHEIGAVKFG NFKLKSGIFS PVYIDLRLIV SYPSLLTQIS QTLISSLPPS ATFDVVCGVP YTALPIATVV SVSNGIPMLM RRKEIKDYGT
101: SKAIEGIFEK DQTCLIIEDL VTSGASVLET AAPLRAVGLK VSDAVVLIDR QQGGRENLAE NGIKLHSMIM LTDMVRVLKE KGKIEVEVEV NLLKFLEENR
201: RVSVPSVEKP KPKPRVLGFK ERSELSKNPT GKKLFDIMLK KETNLCLAAD VGTAAELLDI ADKVGPEICL LKTHVDILPD FTPDFGSKLR AIADKHKFLI
301: FEDRKFADIG NTVTMQYEGG IFKILEWADI INAHVISGPG IVDGLKLKGM PRGRGLLLLA EMSSAGNLAT GDYTAAAVKI ADAHSDFVMG FISVNPASWK
401: CGYVYPSMIH ATPGVQMVKG GDALGQQYNT PHSVITERGS DIIIVGRGII KAENPAETAH EYRVQGWNAY LEKCSQ
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)