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AT2G44160.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:21433285 (2011): plasma membrane
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : methylenetetrahydrofolate reductase 2
Curator
Summary (TAIR10)
methylenetetrahydrofolate reductase MTHFR2 mRNA, complete
Computational
Description (TAIR10)
methylenetetrahydrofolate reductase 2 (MTHFR2); FUNCTIONS IN: methylenetetrahydrofolate reductase (NADPH) activity; INVOLVED IN: oxidation reduction, methionine metabolic process; EXPRESSED IN: male gametophyte, guard cell, cultured cell, leaf; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Methylenetetrahydrofolate reductase (InterPro:IPR003171), Eukaryotic-type methylenetetrahydrofolate reductase (InterPro:IPR004621); BEST Arabidopsis thaliana protein match is: methylenetetrahydrofolate reductase 1 (TAIR:AT3G59970.3); Has 4605 Blast hits to 4574 proteins in 1845 species: Archae - 16; Bacteria - 3444; Metazoa - 135; Fungi - 300; Plants - 75; Viruses - 0; Other Eukaryotes - 635 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G44160-MONOMERBioGrid:4358BRENDA:1.5.1.20EC:1.5.1.20
eggNOG:COG0685eggNOG:KOG0564EMBL:AC004005EMBL:AF181967
EMBL:AF370515EMBL:AJ245414EMBL:AK220952EMBL:AY050434
EMBL:CP002685EnsemblPlants:AT2G44160EnsemblPlants:AT2G44160.1entrez:819022
Gene3D:3.20.20.220GeneID:819022Genevisible:O80585GO:GO:0004489
GO:GO:0005829GO:GO:0006555GO:GO:0006730GO:GO:0035999
Gramene:AT2G44160.1hmmpanther:PTHR21091hmmpanther:PTHR21091:SF31HOGENOM:HOG000246234
InParanoid:O80585IntAct:O80585InterPro:IPR003171InterPro:IPR004621
InterPro:IPR029041iPTMnet:O80585KEGG:00670+1.5.1.20KEGG:00720+1.5.1.20
KEGG:ath:AT2G44160KO:K00297OMA:YPEADPSPaxDb:O80585
Pfam:O80585Pfam:PF02219PhylomeDB:O80585PIR:T00696
PRIDE:O80585PRO:PR:O80585ProteinModelPortal:O80585Proteomes:UP000006548
Reactome:R-ATH-196757RefSeq:NP_566011.1SMR:O80585STRING:3702.AT2G44160.1
SUPFAM:SSF51730TAIR:AT2G44160tair10-symbols:MTHFR2TIGRfam:TIGR00677
TIGRFAMs:TIGR00677UniGene:At.11693UniGene:At.23509UniPathway:UPA00193
UniProt:O80585
Coordinates (TAIR10) chr2:+:18262301..18265185
Molecular Weight (calculated) 66805.70 Da
IEP (calculated) 5.15
GRAVY (calculated) -0.29
Length 594 amino acids
Sequence (TAIR10)
(BLAST)
001: MKVIDKIQSL ADEGKTAFSF EFFPPKTEDG VDNLFERMDR MVAYGPTFCD ITWGAGGSTA DLTLDIASRM QNVVCVESMM HLTCTNMPVE KIDHALETIR
101: SNGIQNVLAL RGDPPHGQDK FVQVEGGFDC ALDLVNHIRS KYGDYFGITV AGYPEAHPDV IGENGLASNE AYQSDLEYLK KKIDAGADLI VTQLFYDTDI
201: FLKFVNDCRQ IGISCPIVPG IMPINNYRGF LRMTGFCKTK IPVEVMAALE PIKDNEEAVK AYGIHLGTEM CKKMLAHGVK SLHLYTLNME KSALAILMNL
301: GMIDESKISR SLPWRRPANV FRTKEDVRPI FWANRPKSYI SRTKGWEDFP QGRWGDSRSA SYGALSDHQF SRPRARDKKL QQEWVVPLKS VEDIQEKFKE
401: LCLGNLKSSP WSELDGLQPE TRIINEQLIK VNSKGFLTIN SQPSVNAERS DSPTVGWGGP VGYVYQKAYL EFFCSKEKLD AVVEKCKALP SITYMAVNKG
501: EQWVSNTAQA DVNAVTWGVF PAKEIIQPTI VDPASFNVWK DEAFETWSRS WANLYPEADP SRNLLEEVKN SYYLVSLVEN DYINGDIFAV FADL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)