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AT4G35830.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
mitochondrion 0.500
ASURE: cytosol,mitochondrion
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31023727 (2019): mitochondrion
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:24727099 (2014): mitochondrion
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:22215637 (2012): plasma membrane
  • PMID:21472856 (2011): mitochondrion
  • PMID:21311031 (2011): mitochondrion
  • PMID:21296373 (2011): mitochondrion
  • PMID:21166475 (2011): cytosol
  • PMID:17644812 (2007): plasma membrane
  • PMID:14671022 (2004): mitochondrion
FP Images

Arabidopsis cell culture (mitochondrial marker)

At4g35830-GFP
(full-length)
mitochondrial marker-RFPoverlay

Images by Sandra Tanz

Arabidopsis cell culture (plastidal marker)

At4g35830-GFP (AA 1-100)plastidal marker-RFPoverlay

Images by Sandra Tanz
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : aconitase 1
Curator
Summary (TAIR10)
Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. This enzyme can also specifically bind to the 5' UTR of CSD2 in vitro.
Computational
Description (TAIR10)
aconitase 1 (ACO1); FUNCTIONS IN: aconitate hydratase activity, copper ion binding, mRNA 5'-UTR binding; INVOLVED IN: response to salt stress, isocitrate metabolic process, citrate metabolic process; LOCATED IN: cytosol, mitochondrion, apoplast, plasma membrane, vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Aconitase family, 4Fe-4S cluster binding site (InterPro:IPR018136), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (InterPro:IPR001030), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (InterPro:IPR015932), Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase (InterPro:IPR015934), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (InterPro:IPR015931), Aconitase/iron regulatory protein 2 (InterPro:IPR006249); BEST Arabidopsis thaliana protein match is: aconitase 3 (TAIR:AT2G05710.1); Has 20862 Blast hits to 20684 proteins in 2607 species: Archae - 544; Bacteria - 10896; Metazoa - 494; Fungi - 666; Plants - 229; Viruses - 0; Other Eukaryotes - 8033 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-152-MONOMERBioCyc:MetaCyc:AT4G35830-MONOMERBioGrid:15019EC:4.2.1.3
eggNOG:COG1048eggNOG:KOG0452EMBL:AL031986EMBL:AL161588
EMBL:AY062772EMBL:CP002687EMBL:X82839EnsemblPlants:AT4G35830
EnsemblPlants:AT4G35830.1entrez:829737ExpressionAtlas:Q42560Gene3D:3.20.19.10
Gene3D:3.30.499.10Gene3D:3.40.1060.10GeneID:829737Genevisible:Q42560
GO:GO:0003994GO:GO:0005507GO:GO:0005739GO:GO:0005773
GO:GO:0005829GO:GO:0005886GO:GO:0006099GO:GO:0006101
GO:GO:0006102GO:GO:0009506GO:GO:0009651GO:GO:0048027
GO:GO:0048046GO:GO:0051539gramene_pathway:4.2.1.3gramene_pathway:GLYOXYLATE-BYPASS
gramene_pathway:PWY-5690gramene_pathway:PWY-6549gramene_pathway:PWYQT-4481gramene_plant_reactome:1119533
gramene_plant_reactome:1119540gramene_plant_reactome:6873406gramene_plant_reactome:6875928hmmpanther:PTHR11670
hmmpanther:PTHR11670:SF40HOGENOM:HOG000025704InParanoid:Q42560IntAct:Q42560
InterPro:IPR000573InterPro:IPR001030InterPro:IPR006249InterPro:IPR015928
InterPro:IPR015931InterPro:IPR015932InterPro:IPR015937InterPro:IPR018136
iPTMnet:Q42560KEGG:00020+4.2.1.3KEGG:00290+4.2.1.33KEGG:00630+4.2.1.3
KEGG:00720+4.2.1.3OMA:ETGQVYDPANTHER:PTHR11670PaxDb:Q42560
Pfam:PF00330Pfam:PF00694Pfam:Q42560PhylomeDB:Q42560
PIR:T04693PRIDE:Q42560PRINTS:PR00415PRO:PR:Q42560
PROSITE:PS00450PROSITE:PS01244ProteinModelPortal:Q42560Proteomes:UP000006548
RefSeq:NP_195308.1scanprosite:PS00450scanprosite:PS01244SMR:Q42560
STRING:3702.AT4G35830.1SUPFAM:SSF52016SUPFAM:SSF53732TAIR:AT4G35830
tair10-symbols:ACO1TIGRfam:TIGR01341TIGRFAMs:TIGR01341UniGene:At.24717
unipathway:UPA00048UniPathway:UPA00223UniProt:Q42560
Coordinates (TAIR10) chr4:-:16973007..16977949
Molecular Weight (calculated) 98157.60 Da
IEP (calculated) 6.36
GRAVY (calculated) -0.16
Length 898 amino acids
Sequence (TAIR10)
(BLAST)
001: MASENPFRSI LKALEKPDGG EFGNYYSLPA LNDPRIDKLP YSIRILLESA IRNCDEFQVK SKDVEKILDW ENTSPKQVEI PFKPARVLLQ DFTGVPAVVD
101: LACMRDAMNN LGGDSNKINP LVPVDLVIDH SVQVDVARSE NAVQANMELE FQRNKERFAF LKWGSNAFHN MLVVPPGSGI VHQVNLEYLA RVVFNTNGLL
201: YPDSVVGTDS HTTMIDGLGV AGWGVGGIEA EATMLGQPMS MVLPGVVGFK LTGKLRDGMT ATDLVLTVTQ MLRKHGVVGK FVEFHGEGMR ELSLADRATI
301: ANMSPEYGAT MGFFPVDHVT LQYLRLTGRS DDTVSMIEAY LRANKMFVDY SEPESKTVYS SCLELNLEDV EPCVSGPKRP HDRVPLKEMK ADWHSCLDNR
401: VGFKGFAVPK EAQSKAVEFN FNGTTAQLRH GDVVIAAITS CTNTSNPSVM LGAALVAKKA CDLGLEVKPW IKTSLAPGSG VVTKYLAKSG LQKYLNQLGF
501: SIVGYGCTTC IGNSGDIHEA VASAIVDNDL VASAVLSGNR NFEGRVHPLT RANYLASPPL VVAYALAGTV DIDFETQPIG TGKDGKQIFF RDIWPSNKEV
601: AEVVQSSVLP DMFKATYEAI TKGNSMWNQL SVASGTLYEW DPKSTYIHEP PYFKGMTMSP PGPHGVKDAY CLLNFGDSIT TDHISPAGSI HKDSPAAKYL
701: MERGVDRRDF NSYGSRRGND EIMARGTFAN IRIVNKHLKG EVGPKTVHIP TGEKLSVFDA AMKYRNEGRD TIILAGAEYG SGSSRDWAAK GPMLLGVKAV
801: ISKSFERIHR SNLVGMGIIP LCFKAGEDAE TLGLTGQELY TIELPNNVSE IKPGQDVTVV TNNGKSFTCT LRFDTEVELA YFDHGGILQY VIRNLIKQ
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)