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AT2G26300.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:26781341 (2016): plasma membrane
  • PMID:24030099 (2013): plasma membrane
  • PMID:22923678 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:20374526 (2010): plasma membrane
  • PMID:17644812 (2007): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:16618929 (2006): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : G protein alpha subunit 1
Curator
Summary (TAIR10)
Encodes an alpha subunit of a heterotrimeric GTP-binding protein. The active GTP-bound form of GPA1 binds to the GTG1 and GTG2 abscisic acid (ABA) receptors and appears to affect their GTPase and GTP-binding activity, and hence, ABA binding abilities. GPA1 is a positive regulator in ABA-mediated inhibition of stomatal opening. Plants with recessive mutant alleles have complex phenotypes including: reduced brassinolide response, reduced cell divisions, round leaves, short hypocotyls. It is likely to be involved in the signaling events that trigger unfolded protein response-associated cell death. GPA1 is also involved in sugar signaling.
Computational
Description (TAIR10)
G protein alpha subunit 1 (GP ALPHA 1); FUNCTIONS IN: in 6 functions; INVOLVED IN: in 16 processes; LOCATED IN: plasma membrane, endoplasmic reticulum membrane, heterotrimeric G-protein complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Plant G-protein, alpha subunit (InterPro:IPR002976), Guanine nucleotide binding protein (G-protein), alpha subunit (InterPro:IPR001019), G protein alpha subunit, helical insertion (InterPro:IPR011025); BEST Arabidopsis thaliana protein match is: extra-large GTP-binding protein 3 (TAIR:AT1G31930.3); Has 3745 Blast hits to 3647 proteins in 408 species: Archae - 0; Bacteria - 0; Metazoa - 2360; Fungi - 766; Plants - 268; Viruses - 0; Other Eukaryotes - 351 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G26300-MONOMERBioGrid:2522DIP:DIP-31793NeggNOG:ENOG410XNVQ
eggNOG:KOG0082EMBL:AC004484EMBL:AF385704EMBL:AY093966
EMBL:CP002685EMBL:M32887EnsemblPlants:AT2G26300EnsemblPlants:AT2G26300.1
entrez:817170Gene3D:1.10.400.10Gene3D:3.40.50.300GeneID:817170
Genevisible:P18064GO:GO:0001789GO:GO:0003924GO:GO:0004871
GO:GO:0005095GO:GO:0005525GO:GO:0005789GO:GO:0005834
GO:GO:0005886GO:GO:0006571GO:GO:0008219GO:GO:0009094
GO:GO:0009506GO:GO:0009738GO:GO:0009740GO:GO:0009749
GO:GO:0009785GO:GO:0009788GO:GO:0009789GO:GO:0009845
GO:GO:0010027GO:GO:0010119GO:GO:0010244GO:GO:0016247
GO:GO:0034260GO:GO:0042127GO:GO:0046872GO:GO:0071215
GO:GO:0072593Gramene:AT2G26300.1hmmpanther:PTHR10218hmmpanther:PTHR10218:SF224
HOGENOM:HOG000038730InParanoid:P18064IntAct:P18064InterPro:IPR001019
InterPro:IPR002976InterPro:IPR011025InterPro:IPR027417iPTMnet:P18064
KEGG:ath:AT2G26300KO:K19729MINT:MINT-6743099OMA:SARAXYL
PANTHER:PTHR10218PaxDb:P18064PDB:2XTZPDBsum:2XTZ
Pfam:P18064Pfam:PF00503PhylomeDB:P18064PIR:A35864
PRIDE:P18064PRINTS:PR00318PRINTS:PR01242PRO:PR:P18064
ProteinModelPortal:P18064Proteomes:UP000006548Reactome:R-ATH-399997Reactome:R-ATH-416476
Reactome:R-ATH-416482Reactome:R-ATH-418555Reactome:R-ATH-434316RefSeq:NP_180198.1
SMART:SM00275SMR:P18064STRING:3702.AT2G26300.1SUPFAM:SSF47895
SUPFAM:SSF52540SwissPalm:P18064TAIR:AT2G26300tair10-symbols:ATGPA1
tair10-symbols:GP ALPHA 1tair10-symbols:GPA1UniGene:At.25148UniProt:P18064
Coordinates (TAIR10) chr2:+:11198087..11200822
Molecular Weight (calculated) 44548.30 Da
IEP (calculated) 6.21
GRAVY (calculated) -0.53
Length 383 amino acids
Sequence (TAIR10)
(BLAST)
001: MGLLCSRSRH HTEDTDENTQ AAEIERRIEQ EAKAEKHIRK LLLLGAGESG KSTIFKQIKL LFQTGFDEGE LKSYVPVIHA NVYQTIKLLH DGTKEFAQNE
101: TDSAKYMLSS ESIAIGEKLS EIGGRLDYPR LTKDIAEGIE TLWKDPAIQE TCARGNELQV PDCTKYLMEN LKRLSDINYI PTKEDVLYAR VRTTGVVEIQ
201: FSPVGENKKS GEVYRLFDVG GQRNERRKWI HLFEGVTAVI FCAAISEYDQ TLFEDEQKNR MMETKELFDW VLKQPCFEKT SFMLFLNKFD IFEKKVLDVP
301: LNVCEWFRDY QPVSSGKQEI EHAYEFVKKK FEELYYQNTA PDRVDRVFKI YRTTALDQKL VKKTFKLVDE TLRRRNLLEA GLL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)