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AT4G27630.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : GPCR-type G protein 2
Curator
Summary (TAIR10)
Encodes a GPCR-type G protein receptor with nine predicted transmembrane domains. The protein binds abscisic acid (ABA) and is predicted to function as an ABA receptor. It has GTP-binding and GTPase activity and binds to ABA more effectively in the presence of GDP. GTG2 binds to GPA1, the alpha subunit of the heterotrimeric G protein. GPA1 (in its GTP-bound state) affects the GTP binding and GTPase activity of GTG2 and may act to down-regulate GTG2 binding to ABA. GTG2 is widely expressed throughout the plant and appears to be involved in the regulation of several ABA-dependent responses including seed germination, plant development, and promotion of stomatal closure. GTG2 transcript levels do not appear to change in response to ABA or abiotic stresses.
Computational
Description (TAIR10)
GPCR-type G protein 2 (GTG2); CONTAINS InterPro DOMAIN/s: GPCR 89-related (InterPro:IPR015672), Protein of unknown function DUF3735 (InterPro:IPR022535); BEST Arabidopsis thaliana protein match is: GPCR-type G protein 1 (TAIR:AT1G64990.2); Has 349 Blast hits to 345 proteins in 148 species: Archae - 2; Bacteria - 0; Metazoa - 168; Fungi - 65; Plants - 51; Viruses - 0; Other Eukaryotes - 63 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT4G27630EnsemblPlants:AT4G27630.1entrez:828874hmmpanther:PTHR15948
ncoils:CoilPfam:PF12430Pfam:PF12537tair10-symbols:GTG2
TMHMM:TMhelix
Coordinates (TAIR10) chr4:-:13791980..13795790
Molecular Weight (calculated) 39669.00 Da
IEP (calculated) 8.66
GRAVY (calculated) 0.33
Length 348 amino acids
Sequence (TAIR10)
(BLAST)
001: MLKILSPTCW TTLLKHPFIL KGFFSMPQLV SRIGVIGVTL MAVLSGFGAV NLPYSYISLF IREIEESEIK SLERQLMQSM ETCIAKKKKI LLCQVEVERS
101: LVSEEHQKGK SFFRRFVGTV VRSVQDDQKE QDIKLMEAEV EGLEELSKQL FLEIYELRQA KDAAAFSRTW KGHVQNFLGY ACSIYCVYKM LKSLQSVVFK
201: EAGTKDPVTM MISIFLQFFD IGVDAALLSQ YISLLFIGML IVISVRGFLT NLMKFFFAVS RVGSGSSSNV VLFLSEIMGM YFLSSILLIR KSLRNEYRGI
301: ITDVLGGDIQ FDFYHRWFDA IFVASAFLSL LLLSAHYTSR QIDKHPID
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)