AT5G11260.1
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        Subcellular Consensus (Prediction and Experimental) min:  :max .SUBAcon: nucleus 1.000 ASURE: nucleus What is SUBAcon? | |||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI | 
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| SUBAcon links AGI-AGI relationships | 
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| Description (TAIR10) | protein_coding : Basic-leucine zipper (bZIP) transcription factor family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) | Basic leucine zipper (bZIP) transcription factor. Nuclear localization. Involved in light-regulated transcriptional activation of G-box-containing promoters. Negatively regulated by Cop1. Although cytokinins do not appear to affect the gene's promoter activity, they appear to stabilize the protein. HY5 plays a role in anthocyanin accumulation in far-red light and blue light, but not in red light or in the dark. Mutant studies showed that the gene product is involved in the positive regulation of the PHYA-mediated inhibition of hypocotyl elongation. Binds to G- and Z-boxes, and other ACEs, but not to E-box. Loss of function mutation shows ABA resistant seedling phenotypes suggesting involvement for HY5 in mediating ABA responses. Binds to the promoter of ABI5 and regulates its expression. | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) | ELONGATED HYPOCOTYL 5 (HY5); FUNCTIONS IN: double-stranded DNA binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: in 13 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616), cAMP response element binding (CREB) protein (InterPro:IPR001630); BEST Arabidopsis thaliana protein match is: HY5-homolog (TAIR:AT3G17609.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations | 
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| Coordinates (TAIR10) | chr5:-:3593583..3594800 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 18464.30 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 10.19 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -1.21 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 168 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) | 001: MQEQATSSLA ASSLPSSSER SSSSAPHLEI KEGIESDEEI RRVPEFGGEA VGKETSGRES GSATGQERTQ ATVGESQRKR GRTPAEKENK RLKRLLRNRV 101: SAQQARERKK AYLSELENRV KDLENKNSEL EERLSTLQNE NQMLRHILKN TTGNKRGGGG GSNADASL | ||||||||||||||||||||||||||||||||||||||||||||
| See Also | 
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    Citation
  
  
    If you find this resource useful please cite one of the following publications:
    
    
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)