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AT1G15750.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 0.865
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Transducin family protein / WD-40 repeat family protein
Curator
Summary (TAIR10)
Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top half of the embryo during the transition stage of embryogenesis. It can also interact with IAA12 through the EAR domain of IAA12 and the CTLH domain of TPL. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.
Computational
Description (TAIR10)
TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 22110 Blast hits to 13392 proteins in 605 species: Archae - 36; Bacteria - 4397; Metazoa - 7838; Fungi - 4804; Plants - 2241; Viruses - 6; Other Eukaryotes - 2788 (source: NCBI BLink).
Protein Annotations
BioGrid:23384DIP:DIP-52391NeggNOG:ENOG410XP3KeggNOG:KOG0266EMBL:AC034256EMBL:AY046013EMBL:AY142619
EMBL:CP002684EnsemblPlants:AT1G15750EnsemblPlants:AT1G15750.1EnsemblPlants:AT1G15750.2EnsemblPlants:AT1G15750.3EnsemblPlants:AT1G15750.4entrez:838144
Gene3D:2.130.10.10GeneID:838144Genevisible:Q94AI7GO:GO:0005634GO:GO:0005829GO:GO:0006351GO:GO:0009733
GO:GO:0009867GO:GO:0010051GO:GO:0010072GO:GO:0042803GO:GO:0045892Gramene:AT1G15750.1Gramene:AT1G15750.2
Gramene:AT1G15750.3Gramene:AT1G15750.4hmmpanther:PTHR22847hmmpanther:PTHR22847:SF480HOGENOM:HOG000237725InParanoid:Q94AI7IntAct:Q94AI7
InterPro:IPR001680InterPro:IPR006594InterPro:IPR006595InterPro:IPR015943InterPro:IPR017986InterPro:IPR019775InterPro:IPR027728
iPTMnet:Q94AI7KEGG:ath:AT1G15750OMA:NMLPMSFPANTHER:PTHR22847:SF480PaxDb:Q94AI7Pfam:PF00400Pfam:Q94AI7
Pfscan:PS50082Pfscan:PS50294Pfscan:PS50896Pfscan:PS50897PhylomeDB:Q94AI7PIR:G86291PRIDE:Q94AI7
PRO:PR:Q94AI7PROSITE:PS00678PROSITE:PS50082PROSITE:PS50294PROSITE:PS50896PROSITE:PS50897ProteinModelPortal:Q94AI7
Proteomes:UP000006548RefSeq:NP_001031050.1RefSeq:NP_001031051.1RefSeq:NP_563981.1RefSeq:NP_849672.1scanprosite:PS00678SMART:SM00320
SMART:SM00667SMART:SM00668SMR:Q94AI7STRING:3702.AT1G15750.1SUPFAM:SSF50978TAIR:AT1G15750tair10-symbols:TPL
tair10-symbols:WSIP1UniGene:At.48194UniGene:At.69991UniProt:Q94AI7
Coordinates (TAIR10) chr1:-:5415086..5420359
Molecular Weight (calculated) 124305.00 Da
IEP (calculated) 7.25
GRAVY (calculated) -0.30
Length 1131 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSSLSRELVF LILQFLDEEK FKETVHKLEQ ESGFFFNMKY FEDEVHNGNW DEVEKYLSGF TKVDDNRYSM KIFFEIRKQK YLEALDKHDR PKAVDILVKD
0101: LKVFSTFNEE LFKEITQLLT LENFRENEQL SKYGDTKSAR AIMLVELKKL IEANPLFRDK LQFPTLRNSR LRTLINQSLN WQHQLCKNPR PNPDIKTLFV
0201: DHSCGPPNGA RAPSPVNNPL LGGIPKAGGF PPLGAHGPFQ PTASPVPTPL AGWMSSPSSV PHPAVSAGAI ALGGPSIPAA LKHPRTPPTN ASLDYPSADS
0301: EHVSKRTRPM GISDEVNLGV NMLPMSFSGQ AHGHSPAFKA PDDLPKTVAR TLSQGSSPMS MDFHPIKQTL LLVGTNVGDI GLWEVGSRER LVQKTFKVWD
0401: LSKCSMPLQA ALVKEPVVSV NRVIWSPDGS LFGVAYSRHI VQLYSYHGGE DMRQHLEIDA HVGGVNDISF STPNKQLCVI TCGDDKTIKV WDAATGVKRH
0501: TFEGHEAPVY SVCPHYKENI QFIFSTALDG KIKAWLYDNM GSRVDYDAPG RWCTTMAYSA DGTRLFSCGT SKDGESFIVE WNESEGAVKR TYQGFHKRSL
0601: GVVQFDTTKN RYLAAGDDFS IKFWDMDAVQ LLTAIDGDGG LQASPRIRFN KEGSLLAVSG NENVIKIMAN SDGLRLLHTF ENISSESSKP AINSIAAAAA
0701: AAATSAGHAD RSANVVSIQG MNGDSRNMVD VKPVITEESN DKSKIWKLTE VSEPSQCRSL RLPENLRVAK ISRLIFTNSG NAILALASNA IHLLWKWQRN
0801: ERNATGKATA SLPPQQWQPA SGILMTNDVA ETNPEEAVPC FALSKNDSYV MSASGGKISL FNMMTFKTMA TFMPPPPAAT FLAFHPQDNN IIAIGMDDST
0901: IQIYNVRVDE VKSKLKGHSK RITGLAFSNV LNVLVSSGAD AQLCVWNTDG WEKQRSKVLP LPQGRPNSAP SDTRVQFHQD QAHFLVVHET QLAIYETTKL
1001: ECMKQWAVRE SLAPITHATF SCDSQLVYAS FMDATVCVFS SANLRLRCRV NPSAYLPASL SNSNVHPLVI AAHPQEPNMF AVGLSDGGVH IFEPLESEGK
1101: WGVAPPAENG SASGAPTAPS VGASASDQPQ R
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)