AT4G00450.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : RNA polymerase II transcription mediators | ||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes the Arabidopsis homolog of the transcriptional regulator MED12, is dynamically expressed during embryogenesis and regulates both developmental timing and the radial pattern formation. Involved in flowering time. The mutant enhances the expression of the flowering time (FT) gene. A knockout mutant of this gene showed late-flowering phenotype. | ||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
CENTER CITY (CCT); FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: photoperiodism, flowering, regulation of development, heterochronic, regulation of radial pattern formation; LOCATED IN: mediator complex, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med12 (InterPro:IPR019035); Has 216 Blast hits to 184 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 42; Fungi - 65; Plants - 86; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr4:+:202425..210666 | ||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 249401.00 Da | ||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.99 | ||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.23 | ||||||||||||||||||||||||||||||||||||
| Length | 2253 amino acids | ||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MQRYHAANCT SAVNNSAIGG ASARDSGRAD SSSIGNYSLN SRRPPPLTPY KLKCEKDGLN SRLGPPDFHP PTSNSPEENL TKEYVQFGYK ETVDGLKESE 0101: EIILSQVHTF SKPVVHKCKE AVRKCLRAIN ESRALKRKAG QVYGVPLSGS LLCKPGFPEQ RSCGEETKKR WIESLSQQHK RLRSLADNIP GYRRKTLFEV 0201: LIRNNVPLLR ATWFIKVTYL NQVHCWAINW CDLVLLLFLQ EHLTRHKLLG VSNGQKMLLN ICNTSWMNFC HGIAHFLLSK LEIGHHRCFI QDQCKRIVQH 0301: QQAFTARKHL YILNGGIWCV FYSGTMLKGF FFLISLLIGF SSSYSFVNFH FALLQEKEIF EILQLLLPIV YGVLESIVLS QTYVQSLVAI AVRFIQEPAP 0401: GGSDLVDNSR RAYTLSALIE MVRYLVLAAP DTFVASDFFP LPPSVAACGP NDVSYTSKAY ENLEKLRSNS AEISAQFQGR GVLSRFEFLS FDYTISTIQR 0501: SADDLAKIAS AGYPQHNVAK AVQALDKALS DGDIRAAYSY LFEDLCNGAV DEAWITDVSP CLRSSLRWIG AISTSFVCSV FFLIEWATCD FRDFRAGVPK 0601: DIKFSGRKDC SQVYLVIQLL KQKILGGEFT ARKGKNCRNN FLGVSKPSGS MDAFESPGPL HDIIVCWIDQ HEVHKGGAKR LQLLVFELIR SGIFNPIAYV 0701: RQLIVSGMID VIQPAVDPER RMRHHRILKQ LPGCFVHETL EEAQLFGGDK LSEAVRTYSN ERRLLLRELL VEKGKYWNNL VLSDQKSKKI STSLSSVIFP 0801: RACNAKSNSK GPRKHTKSSV DIRELKERIS ALLQFPGMSC GVETPVRDEF QNSVKRSSGS VYSKMDQPEA TPGCEDCRRA KRPKMNDEKS SCYQGNSPIA 0901: SDEEDNWWIK KGSKTVESSL KVDPQIEITK QVPRGRQKMA RKTQSLAQLQ AARIEGSQGA STSHVCDNKV SCPHHGPGVE GENQKVVDVF RTSTPVDMVS 1001: VGNSLKQLQF VDKRSIAVWL TTAVRQLVEE PQKSSVRVGQ FNRGAPVEEK NTIRWKLGAD ELYSILFLLD ISLDLVSAVK FLLWLLPKAN STPSFAVQGG 1101: RNLVTVPRNV ENNMCEIGEA ILVSSLRRYE NILLSADLVP EAMTALMNRA ASLMSSNGKI SGSAALVYTR YILKRYGSLP SVVEWHNNFK ATSEKKLLSE 1201: LDHTRSGNGE YGNPLGVPAG VDNPDDYLRK KISIGGARPS RVGLSMRDVL QRHVEEATHY LKKLIGTGTM KASLAEKNDD GYQVAQQIVV GLMDCIRQTG 1301: GAAQEGDPSL VSSAVSAIIN SVGLSVARIT DFSLGNIYQN HPSGVDSSNI ARYILRIHIT CLCLLKEALG ERQSRVFEIA LATESSTALT GVFAPVKGSR 1401: GQHQLSPESY DSNANNSTID MSNGTGKMAL SRATKITAAV SALVIGSITH GVITLERIVG LLRLKDYLDF VQFVRRTKSS SNGSARSMGA SKVESPIEVY 1501: VHWFRLLVGN CKTVSEGLVL ELVGESSVVA ISRMQRMLPL KLVFPPAYSI IAFVLWRPFV SNSNSNSSVH EDTHRLYQSL TMAFHDVIKH LPFRDVCFRD 1601: TQGLYELIVA DSTDAEFASV FESHGLDMHL KSVAFAPLRA RLFLNSLIDC KVPSSGYSHE GVSEAKNRHQ GNGTKLVDKL VSVLDCLQPA KFHWQWVELR 1701: LLLNEQALAE KLENHDMPLT DAIRSSCPTS EKPDASENEK NFIQILLTRL LVRPDAVPLF SEVVHLFGRS VEDSMLKQAE WFLAGQDVLF GRKTIRQKLI 1801: IVGESKGLPT KPQFWKPWGW CNSSSSDHIT ANKAGKKRKF EITSIEEGEV IEEGSGSRKV LLPRVLDENS PSVGYGITTE RAFVQLVLPC IDQSSDESRS 1901: TFVNELVRQF SNIEQQLSSV TNRSTTSNKQ MGTASSGSEI SSNKGSTRKG LRGGSPSLAR RSSANTTDTS PPPSPAALRA SMSLRLQFLL RLLPVICGEP 2001: SFKNTRHALA STIVRLLGSR VVYEDYAVCS PRSELSKAET ESTIDPSSMA DLSSEVLFDR LLFVLHGLLS NHQPKWLKPR PSSNESSKDF TLFDRDAAES 2101: LQNELSRMQL PDTIRWRIQA AMPILLPSLR CSLSCQPHSV PPTALTLVQP SGSTAAAGTN QRNSPAISKS GTAAAQGKLK PTMLAPHQQQ EADNTDVVDP 2201: WTLLEDGTSS GLSSSNASNS SDMANLRATC WLKGAVRVRR TDLTYVGSVD DDS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)