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AT4G38600.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:22550958 (2012): plastid
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : HEAT repeat ;HECT-domain (ubiquitin-transferase)
Curator
Summary (TAIR10)
encodes a member of HECT ubiquitin protein ligase family that is involved in trichome cell morphogenesis. Mutants in this gene exhibit supernumerary trichome branches and increased DNA content.
Computational
Description (TAIR10)
KAKTUS (KAK); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: trichome branching, DNA endoreduplication; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024), HECT (InterPro:IPR000569); BEST Arabidopsis thaliana protein match is: ubiquitin-protein ligase 4 (TAIR:AT5G02880.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1759-MONOMERBioGrid:15297EC:6.3.2.-eggNOG:COG5021
eggNOG:KOG0168eggNOG:KOG0170EMBL:AK229635EMBL:AL035540
EMBL:AL161593EMBL:AY265959EMBL:BN000268EMBL:CP002687
EnsemblPlants:AT4G38600EnsemblPlants:AT4G38600.1entrez:830017ExpressionAtlas:Q6WWW4
Gene3D:1.25.10.10GeneID:830017Genevisible:Q6WWW4GO:GO:0004842
GO:GO:0005886GO:GO:0010091GO:GO:0016874GO:GO:0042023
GO:GO:0042787hmmpanther:PTHR11254hmmpanther:PTHR11254:SF73HOGENOM:HOG000238707
InParanoid:Q6WWW4InterPro:IPR000225InterPro:IPR000569InterPro:IPR011989
InterPro:IPR016024iPTMnet:Q6WWW4KEGG:00220+6.3.2.-KEGG:00261+6.3.2.-
KEGG:00380+6.3.2.-ncoils:CoilOMA:EVMLLACPaxDb:Q6WWW4
Pfam:PF00632Pfam:Q6WWW4Pfscan:PS50237PhylomeDB:Q6WWW4
PIR:T05688PIR:T05689PRIDE:Q6WWW4PRO:PR:Q6WWW4
PROSITE:PS50237ProteinModelPortal:Q6WWW4Proteomes:UP000006548RefSeq:NP_849567.2
SMART:SM00119SMART:SM00185SMR:Q6WWW4STRING:3702.AT4G38600.1
SUPFAM:SSF48371SUPFAM:SSF56204TAIR:AT4G38600tair10-symbols:KAK
tair10-symbols:UPL3UniGene:At.47500UniGene:At.708UniPathway:UPA00143
UniProt:Q6WWW4
Coordinates (TAIR10) chr4:-:18041503..18049292
Molecular Weight (calculated) 202939.00 Da
IEP (calculated) 6.05
GRAVY (calculated) -0.28
Length 1888 amino acids
Sequence (TAIR10)
(BLAST)
0001: METRSRKRAE ATSAAPSSSS SSPPPPPSAS GPTTRSKRAR LSSSSSSSLA PTPPSSSTTT RSRSSRSAAA AAPMDTSTDS SGFRRGGRGN RGNNNDNSDK
0101: GKEKEHDVRI RERERERDRA REQLNMDAAA AAARSADEDD DNDSEDGNGG FMHPNMSSAS SALQGLLRKL GAGLDDLLPS SGIGSASSSH LNGRMKKILS
0201: GLRAEGEEGK QVEALTQLCE MLSIGTEDSL STFSVDSFVP VLVGLLNHES NPDIMLLAAR ALTHLCDVLP SSCAAVVHYG AVSCLVARLL TIEYMDLAEQ
0301: SLQALKKISQ EHPTACLRAG ALMAVLSYLD FFSTGVQRVA LSTAANMCKK LPSDASDYVM EAVPLLTNLL QYHDSKVLEY ASICLTRIAE AFAPYPEKLD
0401: ELCNHGLVTQ AASLISTSNS GGGQASLSVS TYTGLIRLLS TCASGSPLGF RTLLLLGISS ILKDILLGSG VSANASVSPA LSRPADQIYE IVNLANELLP
0501: PLPEGVISLP TSTNALVKGS CQKKSSPSTS GKQEDILKIS PREKLLGDQP ELLQQFGLDL LPVLVQIYGS SVNGTIRHKC LSVIGKLMYF SSSEMIQSLI
0601: GDTNISSFLA GVLAWKDPQV LVPALQVAEI LMEKLPETFS KVFVREGVVH AVDQLVLVGK PSHASPTDKD NDCVPGSARS RRYRRRSSNA NSDGNQSEEP
0701: KNPASLTIGA NHNSLDTPTA SFMLRETVSS CAKAFKDKYF PSDGGDVDVG VTDDLLHLKN LCTKLTAGID DHKVKGKGKS KASGPFLGDF SASKEEYLIG
0801: VISEILGEIS KGDGVSTFEF IGSGVVAALL NYFSCGYFSK EKISELNLPK LRQEGLRRFK AFLEVALPFD GNEGKVPPMT VLIQKLQNAL SSLERFPVVL
0901: SHPSRSLSGS ARLSSGLSAL AHPLKLRLCR ASGEKTLRDY SSNIVLIDPL ASLAAVEEFL WPRVQRSESA LKPAAPIGNT EPGTLPSGAG VSSPSSSTPA
1001: STTRRHSSRS RSAINIGDTS KKDPVHEKGT SSSKGKGKGV MKPAQADKGP QTRSNAQKRA VLDKDTQMKP ASGDSSSEDE ELEISPVDID DALVIEEDDI
1101: SDDEDDDNED VLDDSLPMCT PDKVHDVKLA DSVDDDGLAT SGRQMNPASG GTSGAAAARA SDSIDTGIGN SYGSRGALSF AAAAMAGLGA ASGRGIRGSR
1201: DLHGRTLNRS SDEPSKLIFT AAGKQLSRHL TIYQAVQRQL MLDEDDDDRF GGSDLVSSDG SRFNDIYTIM YQRPDSQVNR LSVGGASSTT PSKSTKSATT
1301: NSSVESQSHR ASLLDSILQG ELPCDLEKSN STYNVLALLR VLEGLNQLCP RLRAQTLSDR FAEGKITSLD DLSTTAAKVP LDEFVNSKLT PKLARQIQDA
1401: LALCSGSLPS WCYQLTRACP FLFPFQTRRQ YFYSTAFGLS RALNRLQQQQ GADGSGSTNE REMRIGRLQR QKVRVSRNRI LDSAAKVMEM YSSQKAVLEV
1501: EYFGEVGTGL GPTLEFYTLL SHDLQKASLG MWRSSSGDKV SMQIGRDEIE DGKPSAANRD IVLAPLGLFP RPWPSTADIS EGGQFHKVIE YFRLLGRVMA
1601: KALQDGRLLD VPLSTAFYKL ILGQELDLHD IVLFDAELGK TLQELRVVVA RKHYLEGVGG DNSSTISDLC LRGCRIEDLS LEFTLPGYPE YILRSGDEIV
1701: DITNLEEYIS LVVDATVKRG VTRQIEAFRS GFNQVFDITS LQIFTPSELD YLLCGRRELW EVETLAEHIK FDHGYNAKSP AIINLLEIMG ELTADQQRAF
1801: CQFVTGAPRL PPGGLAVLNP KLTIVRKHSS TSSAAANGAG ASETADDDLP SVMTCANYLK LPPYSTKEIM YKKLLYAINE GQGSFDLS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)