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AT1G70320.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:19334764 (2009): plasma membrane
  • PMID:18433157 (2008): cytosol
  • PMID:18433157 (2008): nucleus
  • PMID:14671022 (2004): mitochondrion
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : ubiquitin-protein ligase 2
Curator
Summary (TAIR10)
encodes a ubiquitin-protein ligase-like protein containing a HECT domain. There are six other HECT-domain UPLs in Arabidopsis.
Computational
Description (TAIR10)
ubiquitin-protein ligase 2 (UPL2); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: cytosol, mitochondrion, ubiquitin ligase complex, nucleus; EXPRESSED IN: male gametophyte, cultured cell, pollen tube; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), E3 ubiquitin ligase, domain of unknown function DUF913 (InterPro:IPR010314), HECT (InterPro:IPR000569), Armadillo-type fold (InterPro:IPR016024), Ubiquitin interacting motif (InterPro:IPR003903), E3 ubiquitin ligase, domain of unknown function DUF908 (InterPro:IPR010309), UBA-like (InterPro:IPR009060); BEST Arabidopsis thaliana protein match is: ubiquitin-protein ligase 1 (TAIR:AT1G55860.2); Has 34660 Blast hits to 19733 proteins in 1213 species: Archae - 286; Bacteria - 8191; Metazoa - 9374; Fungi - 5439; Plants - 1788; Viruses - 520; Other Eukaryotes - 9062 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-2301-MONOMERBioGrid:28588EC:6.3.2.-eggNOG:COG5021
eggNOG:KOG0939EMBL:AC003671EMBL:AF127565EMBL:AK230373
EMBL:BT002065EMBL:BT008830EMBL:CP002684EnsemblPlants:AT1G70320
EnsemblPlants:AT1G70320.1entrez:843368Gene3D:1.25.10.10GeneID:843368
Genevisible:Q8H0T4GO:GO:0004842GO:GO:0005634GO:GO:0005739
GO:GO:0005829GO:GO:0016874GO:GO:0042787Gramene:AT1G70320.1
hmmpanther:PTHR11254hmmpanther:PTHR11254:SF291HOGENOM:HOG000084686InParanoid:Q8H0T4
IntAct:Q8H0T4InterPro:IPR000569InterPro:IPR003903InterPro:IPR009060
InterPro:IPR010309InterPro:IPR010314InterPro:IPR011989InterPro:IPR015940
InterPro:IPR016024InterPro:IPR025527iPTMnet:Q8H0T4KEGG:00220+6.3.2.-
KEGG:00261+6.3.2.-KEGG:00380+6.3.2.-KEGG:ath:AT1G70320KO:K10592
MINT:MINT-8063873ncoils:CoilOMA:ATINSQRPaxDb:Q8H0T4
Pfam:PF00627Pfam:PF00632Pfam:PF06012Pfam:PF06025
Pfam:PF14377Pfam:Q8H0T4Pfscan:PS50030Pfscan:PS50237
Pfscan:PS50330PIR:T01490PIR:T01491PRIDE:Q8H0T4
PRO:PR:Q8H0T4PROSITE:PS50030PROSITE:PS50237PROSITE:PS50330
ProteinModelPortal:Q8H0T4Proteomes:UP000006548RefSeq:NP_177189.1SMART:SM00119
SMART:SM00165STRING:3702.AT1G70320.1SUPFAM:SSF46934SUPFAM:SSF48371
SUPFAM:SSF56204TAIR:AT1G70320tair10-symbols:UPL2UniGene:At.46269
UniPathway:UPA00143UniProt:Q8H0T4
Coordinates (TAIR10) chr1:-:26488745..26501281
Molecular Weight (calculated) 403639.00 Da
IEP (calculated) 4.56
GRAVY (calculated) -0.23
Length 3658 amino acids
Sequence (TAIR10)
(BLAST)
0001: MKLRRRRASE VPTKISLFIN SVTSVPLELI QEPLASFRWE FDKGDFHHWV DLFYHFDTFF EKHVKVRKDL RIEEEFDESD PPFPKDAVLQ VLRVIRLVLE
0101: NCTNKQFYTS YEQHLSLLLA STDADVVEAC LQTLAAFLKR PTGKYSIRDA SLNLKLFSLA QGWGGKEEGL GLTSCATEHS CDQLFLQLGC TLLFEFYASD
0201: ESPSELPGGL QVIHVPDVSM RSESDLELLN KLVIDHNVPP SLRFALLTRL RFARAFSSLA TRQQYTCIRL YAFIVLVQAS GDTENVVSFF NGEPEFVNEL
0301: VTLVSYEDTV PAKIRILCLQ SLVALSQDRT RQPTVLTAVT SGGHRGLLSG LMQKAIDSVI CNTSKWSLAF AEALLSLVTV LVSSSSGCSA MREAGLIPTL
0401: VPLIKDTDPQ HLHLVSTAVH ILEVFMDYSN PAAALFRDLG GLDDTIFRLK QEVSRTEDDV KEIVCCSGSN GPEDDTEQLP YSEALISYHR RLLLKALLRA
0501: ISLGTYAPGN TNLYGSEESL LPECLCIIFR RAKDFGGGVF SLAATVMSDL IHKDPTCFNA LDSAGLTSAF LDAISDEVIC SAEAITCIPQ CLDALCLNNS
0601: GLQAVKDRNA LRCFVKIFSS PSYLKALTSD TPGSLSSGLD ELLRHQSSLR TYGVDMFIEI LNSILIIGSG MEATTSKSAD VPTDAAPVPM EIDVDEKSLA
0701: VSDEAEPSSD TSPANIELFL PDCVCNVARL FETVLQNAEV CSLFVEKKGI DTVLQLFSLP LMPLSTSLGQ SFSVAFKNFS PQHSAGLARI LCSYLREHLK
0801: KTNNLLVSIE GTQLLKLESA VQTKILRSLS CLEGMLSLSN FLLKGSASVI SELSAANADV LKELGITYKQ TIWQMALCND TKEDEKKSVD RASDNSVSAS
0901: SSTAERESDE DSSNALAVRY TNPVSIRSSS SQSIWGGHRE FLSVVRSGRG VHGHTRHAIA RMRGGRTRRH LESFNFDSEI PADLPVTSSS HELKKKSTEV
1001: LIAEILNKLN CTLRFFFTSL VKGFTSANRR RIDGPSLSSA SKTLGTALAK VFLEALNFQG YGAAAGPDTS LSLKCRYLGK VVDDITFLTF DTRRRVCFTA
1101: MVNSFYVHGT FKELLTTFEA TSQLLWKVPF SIRASSTENE KSGERNLWSH SKWLVDTLQN YCRALDYFVN STYLLSPTSQ TQLLVQPASV DLSIGLFPVP
1201: REPETFVRNL QSQVLEVILP IWNHPMFPDC NPNFVASVTS LVTHIYSGVV DTRENRSGAT QGTNQRALPL QPDEAIVGMI VEMGFSRSRA EDALRRVGTN
1301: SVEMAMDWLF TNPEDPVQED DELAQALALS LGNSSETPKL EDTEKPVDVP QEEAEPKEPP VDEVIAASVK LFQSDDSIAF PLVDLFVTLC NRNKGEDRPK
1401: IVFYLIQQLK LVQLDFSKDT GALTMIPHIL ALVLSEDDNT REIAAQDGIV AVAIGILTDF NLKSESETDI LAPKCISALL LVLSMMLQAQ TRLSSEYVEG
1501: NQGGSLVLSD SPQDSTAALK DALSSDVAKG ESNQALESMF GKSTGYLTME ESSKVLLIAC GLIKQRVPAM IMQAVLQLCA RLTKSHALAI QFLENGGLSS
1601: LFNLPKKCFF PGYDTVASVI VRHLVEDPQT LQIAMETEIR QTLSGKRHIG RVLPRTFLTT MAPVISRDPV VFMKAVASTC QLESSGGTDF VILTKEKEKP
1701: KVSGSEHGFS LNEPLGISEN KLHDGSGKCS KSHRRVPTNF IQVIDQLIDI VLSFPGLKRQ EGEAANLISM DVDEPTTKVK GKSKVGEPEK AELGSEKSEE
1801: LARVTFILKL LSDIVLMYLH GTSVILRRDT EISQLRGSNL PDDSPGNGGL IYHVIHRLLP ISLEKFVGPE EWKEKLSEKA SWFLVVLCSR SNEGRKRIIN
1901: ELTRVLSVFA SLGRSSSQSV LLPDKRVLAF ANLVYSILTK NSSSSNFPGC GCSPDVAKSM IDGGTIQCLT SILNVIDLDH PDAPKLVTLI LKSLETLTRA
2001: ANAAEQLKSE VPNEQKNTDS DERHDSHGTS TSTEVDELNQ NNSSLQQVTD AVDNGQEQPQ VSSQSEGERG SSLTQAMLQE MRIEGDETIL PEPIQMDFFR
2101: EEIEGDQIEM SFHVEDRADD DVDDDMDDEG EDDEGDDEDA DSVEDGAGVM SIAGTDVEDP EDTGLGDEYN DDMVDEDEED EDEYNDDMVD EDEDDEDEYN
2201: DDMVDEDEDD FHETRVIEVR WREALDGLDH FQIVGRSGGG NGFIDDITAE PFEGVNVDDL FALRRSLGFE RRRQTGRSSF DRSGSEVHGF QHPLFSRPSQ
2301: TGNTASVSAS AGSISRHSEA GSYDVAQFYM FDSPVLPFDQ VPVDPFSDRL GGGGAPPPLT DYSVVGMDSS RRGVGDSRWT DVGHPQPSSL SASIAQLIEE
2401: HFITNLRASA PVDTVVERET NTTEVQEQQQ PDVPPSVGSE TVLGDGNEGG EQSEEHELLN NNEVMHPLPL NSTPNEIDRM EVGEGGGAPI EQVDREAVHL
2501: ISSAQGQSDT SGIQNVSVTA IPPPVDDPDS NFQPSVDVDM SSDGAEGNQS VQPSPLDGDN NELSSMEATQ DVRNDEQVDE GSLDGRAPEV NAIDPTFLEA
2601: LPEDLRAEVL ASQQAQSVQP PTYEPPSVDD IDPEFLAALP PEIQREVLAQ QRAQRMLQQS QGQPVDMDNA SIIATLPADL REEVLLTSSE AVLAALPPPL
2701: LAEAQMLRDR AMRHYQARSR VFGSSHRLNN RRNGLGYRLT GMERGVGVTI GQRDVSSSAD GLKVKEIEGD PLVNADALKS LIRLLRLAQP LGKGLLQRLL
2801: LNLCAHSFTR ANLVQLLLDM IRPEMETLPS ELALTNPQRL YGCQLNVVYG RSQLLNGLPP LVFRRVLEVL TYLATNHSAV ADMLFYFDSS LLSQLSSRKG
2901: KEKVTHETDS RDLEIPLVVF LKLLNRPQLL QSTSHLALVM GLLQVVVYTA ASRIEGWSPS SGVPEKLENK PVGEEASSET QKDAESELSV ARRKNCAELY
3001: NIFLQLPQSD LCNLCMLLGY EGLSDKIYSL AGEVLKKLAA VDVTHRKFFT KELSELASGL SSSTVRVLAT LSTTQKMSQN TCSMAGASIL RVLQVLSSLT
3101: STIDDSNVGT DKETDQEEQN IMQGLKVALE PLWQELGQCI SMTELQLDHT AATSNVNPGD HVLGISPTSS LSPGTQSLLP LIEAFFVLCE KIQTPSMLQQ
3201: DATVTAGEVK ESSTHGSSSK TIVDSQKKID GSVTFSKFVE KHRRLLNSFV RQNPSLLEKS FSMMLKAPRL IDFDNKKAYF RSRIRHQHDQ HISGPLRISV
3301: RRAYVLEDSY NQLRMRSPQD LKGRLNVQFQ GEEGIDAGGL TREWYQLLSR VIFDKGALLF TTVGNDATFQ PNPNSVYQTE HLSYFKFVGR MVAKALFDGQ
3401: LLDVYFTRSF YKHILGVKVT YHDIEAVDPD YYKNLKWLLE NDVSDILDLT FSMDADEEKH ILYEKTEVTD YELKPGGRNI RVTEETKHEY VDLVADHILT
3501: SAIRPQINAF LEGLNELIPR ELVSIFNDKE LELLISGLPE IDFDDLKANT EYTSYTVGSP VIRWFWEVVK AFSKEDMARF LQFVTGTSKV PLEGFKALQG
3601: ISGPQRLQIH KAYGSPERLP SAHTCFNQLD LPEYQSKEQV QERLLLAIHE ANEGFGFA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)