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AT1G50030.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31818904 (2020): mitochondrion
  • PMID:31520498 (2020): mitochondrion
  • PMID:31023727 (2019): mitochondrion
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : target of rapamycin
Curator
Summary (TAIR10)
Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems.
Computational
Description (TAIR10)
target of rapamycin (TOR); FUNCTIONS IN: protein binding, 1-phosphatidylinositol-3-kinase activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), Armadillo-like helical (InterPro:IPR011989), FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (InterPro:IPR009076), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), PIK-related kinase (InterPro:IPR014009), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 4645 Blast hits to 4114 proteins in 299 species: Archae - 0; Bacteria - 46; Metazoa - 1929; Fungi - 1123; Plants - 507; Viruses - 4; Other Eukaryotes - 1036 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G50030-MONOMERBioCyc:ARA:GQT-1674-MONOMERBioGrid:26652DIP:DIP-39421N
EC:2.7.11.1eggNOG:COG5032eggNOG:KOG0891EMBL:AC015445
EMBL:AF178967EMBL:CP002684EnsemblPlants:AT1G50030EnsemblPlants:AT1G50030.1
entrez:841427ExpressionAtlas:Q9FR53Gene3D:1.10.1070.11Gene3D:1.25.10.10
GeneID:841427Genevisible:Q9FR53GO:GO:0000975GO:GO:0004674
GO:GO:0005524GO:GO:0005634GO:GO:0005737GO:GO:0006281
GO:GO:0008144GO:GO:0009303GO:GO:0009791GO:GO:0009793
GO:GO:0010507GO:GO:0016301GO:GO:0016303GO:GO:0030307
GO:GO:0036092GO:GO:0040019GO:GO:0042802GO:GO:0043621
GO:GO:0045893GO:GO:2000234hmmpanther:PTHR11139hmmpanther:PTHR11139:SF9
HOGENOM:HOG000163215InParanoid:Q9FR53IntAct:Q9FR53InterPro:IPR000403
InterPro:IPR003151InterPro:IPR003152InterPro:IPR009076InterPro:IPR011009
InterPro:IPR011989InterPro:IPR014009InterPro:IPR016024InterPro:IPR018936
InterPro:IPR024585InterPro:IPR026683iPTMnet:Q9FR53KEGG:04150+2.7.11.1
KEGG:04151+2.7.11.1MINT:MINT-8177759OMA:AYDQLRHPANTHER:PTHR11139:SF9
PaxDb:Q9FR53Pfam:PF00454Pfam:PF02259Pfam:PF02260
Pfam:PF08771Pfam:PF11865Pfam:PF13646Pfam:Q9FR53
Pfscan:PS50290Pfscan:PS51189Pfscan:PS51190PhylomeDB:Q9FR53
PIR:G96536PRIDE:Q9FR53PRO:PR:Q9FR53PROSITE:PS00915
PROSITE:PS00916PROSITE:PS50290PROSITE:PS51189PROSITE:PS51190
ProteinModelPortal:Q9FR53Proteomes:UP000006548Reactome:R-ATH-3371571RefSeq:NP_175425.2
scanprosite:PS00915scanprosite:PS00916SMART:SM00146SMART:SM01343
SMART:SM01346SMR:Q9FR53STRING:3702.AT1G50030.1SUPFAM:0045511
SUPFAM:SSF47212SUPFAM:SSF48371SUPFAM:SSF56112TAIR:AT1G50030
tair10-symbols:TORUniGene:At.16944UniProt:Q9FR53
Coordinates (TAIR10) chr1:-:18522626..18539619
Molecular Weight (calculated) 279206.00 Da
IEP (calculated) 6.82
GRAVY (calculated) -0.14
Length 2481 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSTSSQSFVA GRPASMASPS QSHRFCGPSA TASGGGSFDT LNRVIADLCS RGNPKEGAPL AFRKHVEEAV RDLSGEASSR FMEQLYDRIA NLIESTDVAE
0101: NMGALRAIDE LTEIGFGENA TKVSRFAGYM RTVFELKRDP EILVLASRVL GHLARAGGAM TSDEVEFQMK TAFDWLRVDR VEYRRFAAVL ILKEMAENAS
0201: TVFNVHVPEF VDAIWVALRD PQLQVRERAV EALRACLRVI EKRETRWRVQ WYYRMFEATQ DGLGRNAPVH SIHGSLLAVG ELLRNTGEFM MSRYREVAEI
0301: VLRYLEHRDR LVRLSITSLL PRIAHFLRDR FVTNYLTICM NHILTVLRIP AERASGFIAL GEMAGALDGE LIHYLPTIMS HLRDAIAPRK GRPLLEAVAC
0401: VGNIAKAMGS TVETHVRDLL DVMFSSSLSS TLVDALDQIT ISIPSLLPTV QDRLLDCISL VLSKSHYSQA KPPVTIVRGS TVGMAPQSSD PSCSAQVQLA
0501: LQTLARFNFK GHDLLEFARE SVVVYLDDED AATRKDAALC CCRLIANSLS GITQFGSSRS TRAGGRRRRL VEEIVEKLLR TAVADADVTV RKSIFVALFG
0601: NQCFDDYLAQ ADSLTAIFAS LNDEDLDVRE YAISVAGRLS EKNPAYVLPA LRRHLIQLLT YLELSADNKC REESAKLLGC LVRNCERLIL PYVAPVQKAL
0701: VARLSEGTGV NANNNIVTGV LVTVGDLARV GGLAMRQYIP ELMPLIVEAL MDGAAVAKRE VAVSTLGQVV QSTGYVVTPY KEYPLLLGLL LKLLKGDLVW
0801: STRREVLKVL GIMGALDPHV HKRNQQSLSG SHGEVPRGTG DSGQPIPSID ELPVELRPSF ATSEDYYSTV AINSLMRILR DASLLSYHKR VVRSLMIIFK
0901: SMGLGCVPYL PKVLPELFHT VRTSDENLKD FITWGLGTLV SIVRQHIRKY LPELLSLVSE LWSSFTLPGP IRPSRGLPVL HLLEHLCLAL NDEFRTYLPV
1001: ILPCFIQVLG DAERFNDYTY VPDILHTLEV FGGTLDEHMH LLLPALIRLF KVDAPVAIRR DAIKTLTRVI PCVQVTGHIS ALVHHLKLVL DGKNDELRKD
1101: AVDALCCLAH ALGEDFTIFI ESIHKLLLKH RLRHKEFEEI HARWRRREPL IVATTATQQL SRRLPVEVIR DPVIENEIDP FEEGTDRNHQ VNDGRLRTAG
1201: EASQRSTKED WEEWMRHFSI ELLKESPSPA LRTCAKLAQL QPFVGRELFA AGFVSCWAQL NESSQKQLVR SLEMAFSSPN IPPEILATLL NLAEFMEHDE
1301: KPLPIDIRLL GALAEKCRVF AKALHYKEME FEGPRSKRMD ANPVAVVEAL IHINNQLHQH EAAVGILTYA QQHLDVQLKE SWYEKLQRWD DALKAYTLKA
1401: SQTTNPHLVL EATLGQMRCL AALARWEELN NLCKEYWSPA EPSARLEMAP MAAQAAWNMG EWDQMAEYVS RLDDGDETKL RGLASPVSSG DGSSNGTFFR
1501: AVLLVRRAKY DEAREYVERA RKCLATELAA LVLESYERAY SNMVRVQQLS ELEEVIEYYT LPVGNTIAEE RRALIRNMWT QRIQGSKRNV EVWQALLAVR
1601: ALVLPPTEDV ETWLKFASLC RKSGRISQAK STLLKLLPFD PEVSPENMQY HGPPQVMLGY LKYQWSLGEE RKRKEAFTKL QILTRELSSV PHSQSDILAS
1701: MVSSKGANVP LLARVNLKLG TWQWALSSGL NDGSIQEIRD AFDKSTCYAP KWAKAWHTWA LFNTAVMSHY ISRGQIASQY VVSAVTGYFY SIACAANAKG
1801: VDDSLQDILR LLTLWFNHGA TADVQTALKT GFSHVNINTW LVVLPQIIAR IHSNNRAVRE LIQSLLIRIG ENHPQALMYP LLVACKSISN LRRAAAQEVV
1901: DKVRQHSGAL VDQAQLVSHE LIRVAILWHE MWHEALEEAS RLYFGEHNIE GMLKVLEPLH DMLDEGVKKD STTIQERAFI EAYRHELKEA HECCCNYKIT
2001: GKDAELTQAW DLYYHVFKRI DKQLASLTTL DLESVSPELL LCRDLELAVP GTYRADAPVV TISSFSRQLV VITSKQRPRK LTIHGNDGED YAFLLKGHED
2101: LRQDERVMQL FGLVNTLLEN SRKTAEKDLS IQRYSVIPLS PNSGLIGWVP NCDTLHHLIR EHRDARKIIL NQENKHMLSF APDYDNLPLI AKVEVFEYAL
2201: ENTEGNDLSR VLWLKSRSSE VWLERRTNYT RSLAVMSMVG YILGLGDRHP SNLMLHRYSG KILHIDFGDC FEASMNREKF PEKVPFRLTR MLVKAMEVSG
2301: IEGNFRSTCE NVMQVLRTNK DSVMAMMEAF VHDPLINWRL FNFNEVPQLA LLGNNNPNAP ADVEPDEEDE DPADIDLPQP QRSTREKEIL QAVNMLGDAN
2401: EVLNERAVVV MARMSHKLTG RDFSSSAIPS NPIADHNNLL GGDSHEVEHG LSVKVQVQKL INQATSHENL CQNYVGWCPF W
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)