AT1G15750.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.851 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Transducin family protein / WD-40 repeat family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top half of the embryo during the transition stage of embryogenesis. It can also interact with IAA12 through the EAR domain of IAA12 and the CTLH domain of TPL. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 22110 Blast hits to 13392 proteins in 605 species: Archae - 36; Bacteria - 4397; Metazoa - 7838; Fungi - 4804; Plants - 2241; Viruses - 6; Other Eukaryotes - 2788 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:5415086..5420359 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 124305.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.25 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.30 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1131 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MSSLSRELVF LILQFLDEEK FKETVHKLEQ ESGFFFNMKY FEDEVHNGNW DEVEKYLSGF TKVDDNRYSM KIFFEIRKQK YLEALDKHDR PKAVDILVKD 0101: LKVFSTFNEE LFKEITQLLT LENFRENEQL SKYGDTKSAR AIMLVELKKL IEANPLFRDK LQFPTLRNSR LRTLINQSLN WQHQLCKNPR PNPDIKTLFV 0201: DHSCGPPNGA RAPSPVNNPL LGGIPKAGGF PPLGAHGPFQ PTASPVPTPL AGWMSSPSSV PHPAVSAGAI ALGGPSIPAA LKHPRTPPTN ASLDYPSADS 0301: EHVSKRTRPM GISDEVNLGV NMLPMSFSGQ AHGHSPAFKA PDDLPKTVAR TLSQGSSPMS MDFHPIKQTL LLVGTNVGDI GLWEVGSRER LVQKTFKVWD 0401: LSKCSMPLQA ALVKEPVVSV NRVIWSPDGS LFGVAYSRHI VQLYSYHGGE DMRQHLEIDA HVGGVNDISF STPNKQLCVI TCGDDKTIKV WDAATGVKRH 0501: TFEGHEAPVY SVCPHYKENI QFIFSTALDG KIKAWLYDNM GSRVDYDAPG RWCTTMAYSA DGTRLFSCGT SKDGESFIVE WNESEGAVKR TYQGFHKRSL 0601: GVVQFDTTKN RYLAAGDDFS IKFWDMDAVQ LLTAIDGDGG LQASPRIRFN KEGSLLAVSG NENVIKIMAN SDGLRLLHTF ENISSESSKP AINSIAAAAA 0701: AAATSAGHAD RSANVVSIQG MNGDSRNMVD VKPVITEESN DKSKIWKLTE VSEPSQCRSL RLPENLRVAK ISRLIFTNSG NAILALASNA IHLLWKWQRN 0801: ERNATGKATA SLPPQQWQPA SGILMTNDVA ETNPEEAVPC FALSKNDSYV MSASGGKISL FNMMTFKTMA TFMPPPPAAT FLAFHPQDNN IIAIGMDDST 0901: IQIYNVRVDE VKSKLKGHSK RITGLAFSNV LNVLVSSGAD AQLCVWNTDG WEKQRSKVLP LPQGRPNSAP SDTRVQFHQD QAHFLVVHET QLAIYETTKL 1001: ECMKQWAVRE SLAPITHATF SCDSQLVYAS FMDATVCVFS SANLRLRCRV NPSAYLPASL SNSNVHPLVI AAHPQEPNMF AVGLSDGGVH IFEPLESEGK 1101: WGVAPPAENG SASGAPTAPS VGASASDQPQ R |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)