suba logo
AT3G04740.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

.
SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : RNA polymerase II transcription mediators
Curator
Summary (TAIR10)
encodes a protein with similarities to subunits of the Mediator complex, required for RNA polymerase II recruitment at target promoters in response to specific activators. Lines carrying loss of function mutations in the gene have reduced cell numbers in aerial organs. On the other hand, lines overexpressing the gene have increased number of small cells in clusters, suggesting cell division is more unsynchronized in the overexpressors.
Computational
Description (TAIR10)
STRUWWELPETER (SWP); FUNCTIONS IN: RNA polymerase II transcription mediator activity; INVOLVED IN: positive regulation of transcription, positive regulation of cell proliferation; LOCATED IN: mediator complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mediator complex, subunit Med14 (InterPro:IPR013947); Has 940 Blast hits to 375 proteins in 163 species: Archae - 0; Bacteria - 61; Metazoa - 117; Fungi - 104; Plants - 74; Viruses - 0; Other Eukaryotes - 584 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410XWK4eggNOG:KOG1875EMBL:AC011437EMBL:AF466359
EMBL:AJ511271EMBL:CP002686EnsemblPlants:AT3G04740EnsemblPlants:AT3G04740.1
entrez:819634GeneID:819634Genevisible:Q9SR02GO:GO:0001104
GO:GO:0006351GO:GO:0007275GO:GO:0008284GO:GO:0009506
GO:GO:0009627GO:GO:0009631GO:GO:0016592GO:GO:0040008
GO:GO:0070847Gramene:AT3G04740.1hmmpanther:PTHR12809hmmpanther:PTHR12809:SF3
HOGENOM:HOG000030663InParanoid:Q9SR02IntAct:Q9SR02InterPro:IPR013947
iPTMnet:Q9SR02KEGG:ath:AT3G04740KO:K15156OMA:MDCEEAL
PaxDb:Q9SR02Pfam:PF08638Pfam:Q9SR02PhylomeDB:Q9SR02
PRIDE:Q9SR02PRO:PR:Q9SR02ProteinModelPortal:Q9SR02Proteomes:UP000006548
RefSeq:NP_187125.1STRING:3702.AT3G04740.1TAIR:AT3G04740tair10-symbols:ATMED14
tair10-symbols:MED14tair10-symbols:SWPUniGene:At.18555UniProt:Q9SR02
Coordinates (TAIR10) chr3:+:1294037..1300555
Molecular Weight (calculated) 185519.00 Da
IEP (calculated) 7.43
GRAVY (calculated) -0.13
Length 1703 amino acids
Sequence (TAIR10)
(BLAST)
0001: MAELGQQTVD FSALVGRAAE ESFLSFKELV DKSKSTELSD TEKKVSLLKY VAKTQQRMLR LNALAKWCKQ VPLINYFQDL GSTLSAHDIC FTQAADSLFF
0101: MHEGLQQARA PVYDVPSAVE ILLTGSYQRL PKCLDDVGMQ SSLDEHQQKP ALRKLEVLVR SKLLEITLPK EITEVKISKG TVTLSVDGEF KVLVTLGYRG
0201: HLSMWRILHL DLLVGERSGP IKLEVTRRHI LGDDLERRMS VAENPFTILY AVLHELCVAI VMDTVIRQVR ALLQGRWKDA IRFDLISDTG TTPANQEGEA
0301: DSVSLRTPGM KLFYWSDSDK NSGPFIKIEP GSDLQIKCSH STFVIDPLTG KEAEFSLDQS CIDVEKLLLK AICCNRYTRL LEIQKELLRN TRICRTPSDV
0401: ILQALLDEPG IEGDNMVDSK ERVEPEVLRV RAYGSSFFTL GINIRTGRFL LQSSKSILTS SILEEFEDAL NQGSISAVDA FINLRSKSIL HFFAAIGKFL
0501: GLEVYEHGFG INKVPKSLLD GSSILTLGFP DCESSHLLLM ELEKDFTPLF KLLETQMDGS GKPQSFNDPS NILRAKKIDI GQIRILEDDL NLITSDVVKF
0601: VSSFSDAEGI NQASGHRQPG LVDEALTEMS GSQLSFSSVV DGVFGLQKVT SALMSIDGHG LVPKNLSAVT GHGKAPMLTS YHSDSLYNRQ GPLQSSSYNM
0701: LSSPPGKGSA MKKIAISNSD QELSLILSPS LSTGNGVSES GSRLVTESSL SPLPLSQTAD LATSSAGPLL RKDQKPRKRS ASDLLRLIPS LQVVEGVASP
0801: NKRRKTSELV QSELVKSWSP ASQTLSTAVS TSTKTIGCSY GNLIAEANKG NAPSSVFVYA LLHVVRHSSL SIKHAKLTSQ MEALDIQYVE EMGLRDAFSD
0901: IWFRLPFAQN DSWQHICLQL GRPGSMCWDV KINDQHFRDL WELQKGSKTT PWGSGVHIAN SSDVDSHIRY DPEGVVLSYQ SVEADSIKKL VADIQRLSNA
1001: RMFSLGMRKL LGIKPDEKTE ECSANSTMKG STGGKGSGEP VDRWRAFKIE AVGLTSLWFS FGSGVLARFV VEWESGKDGC TMHVSPDQLW PHTKFLEDFI
1101: NGAEVESLLD CIRLTAGPLH ALAAATRPAR ASTATGMPVV PATASSRQSN QIQQTQGIIA PSTLAAPNAT GQSASATSGN TVASSAPSPL GGGFHGVAML
1201: AAAGRSGPGI VPSSLLPIDV SVVLRGPYWI RIIYRKRFAV DMRCFAGDQV WLQPATPPKG GASIGGSLPC PQFRPFIMEH VAQELNGLEP NLTGSQGATN
1301: PNSGNPTVNG VNRVNFSPSS ARAAMNRVAS VASGSLVVSS GLPVRRTPGT AVPAHVRGEL NTAIIGLGDD GGYGGGWVPL VALKKVLRGI LKYLGVLWLF
1401: AQLPDLLREI LGSILKDNEG ALLNLDQEQP ALRFFVGGYV FAVSVHRVQL LLQVLSVRRF HHQAQQNGSS AAAQEELTQS EIGEICDYFS RRVASEPYDA
1501: SRVASFITLL TLPISVLREF LKLIAWKKGL SQSQQAGEIA PAQRPRIELC LENHSGTDLD NNCAAKSNIH YDRPHNTVDF ALTVVLDPVH IPHINAAGGA
1601: AWLPYCVSVR LRYTFGENPS VTFLGMEGSH GGRACWQRVD DWEKCKQRVS RTVEVNGSAA GDLTQGKLKL VADSVQRTLH LCLQGLREGG NNNNNTHQKE
1701: FTI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)