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AT4G18780.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
extracellular 0.500
plasma membrane 0.500
ASURE: extracellular,plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:22926318 (2012): Golgi trans-Golgi network
  • PMID:16356755 (2006): extracellular region
  • PMID:15593128 (2005): extracellular region
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : cellulose synthase family protein
Curator
Summary (TAIR10)
Encodes a member of the cellulose synthase family involved in secondary cell wall biosynthesis. Mutants have abnormal xylem formation, reduced cellulose content, and enhanced drought and osmotic stress tolerance. Mediates resistance towards bacterial pathogens via ABA. Confers resistance towards bacterial and fungal pathogens, independent of salicylic acid, ethylene and jasmonate signaling.
Computational
Description (TAIR10)
IRREGULAR XYLEM 1 (IRX1); FUNCTIONS IN: cellulose synthase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: in 7 processes; LOCATED IN: cell wall, plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cellulose synthase (InterPro:IPR005150); BEST Arabidopsis thaliana protein match is: cellulose synthase A4 (TAIR:AT5G44030.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:MetaCyc:MONOMER-2366BioGrid:12905BRENDA:2.4.1.12CAZy:GT2
EC:2.4.1.12eggNOG:COG1215eggNOG:ENOG410IGV4EMBL:AF267742
EMBL:AL035526EMBL:AL161549EMBL:AY099636EMBL:CP002687
EnsemblPlants:AT4G18780EnsemblPlants:AT4G18780.1entrez:827612ExpressionAtlas:Q8LPK5
Gene3D:3.30.40.10GeneID:827612Genevisible:Q8LPK5GO:GO:0005618
GO:GO:0005886GO:GO:0006970GO:GO:0009414GO:GO:0009834
GO:GO:0016021GO:GO:0016760GO:GO:0030244GO:GO:0042742
GO:GO:0046872GO:GO:0050832GO:GO:0071555Gramene:AT4G18780.1
gramene_pathway:2.4.1.12gramene_pathway:PWY-1001gramene_plant_reactome:1119314gramene_plant_reactome:6875373
hmmpanther:PTHR13301hmmpanther:PTHR13301:SF31HOGENOM:HOG000241942InParanoid:Q8LPK5
IntAct:Q8LPK5InterPro:IPR005150InterPro:IPR013083InterPro:IPR027934
InterPro:IPR029044KEGG:00500+2.4.1.12KEGG:ath:AT4G18780KO:K10999
MINT:MINT-6950961OMA:WCGCCSCPaxDb:Q8LPK5Pfam:PF03552
Pfam:PF14569Pfam:Q8LPK5PhylomeDB:Q8LPK5PIR:T04870
PRIDE:Q8LPK5PRO:PR:Q8LPK5ProteinModelPortal:Q8LPK5Proteomes:UP000006548
RefSeq:NP_567564.1SMR:Q8LPK5STRING:3702.AT4G18780.1SUPFAM:SSF53448
SUPFAM:SSF57850TAIR:AT4G18780tair10-symbols:ATCESA8tair10-symbols:CESA8
tair10-symbols:IRX1tair10-symbols:LEW2TCDB:4.D.3.1.7TMHMM:TMhelix
UniGene:At.66621UniGene:At.68239UniPathway:UPA00695UniProt:A0A068FHR7
UniProt:Q8LPK5
Coordinates (TAIR10) chr4:-:10312846..10316719
Molecular Weight (calculated) 111527.00 Da
IEP (calculated) 7.13
GRAVY (calculated) -0.10
Length 985 amino acids
Sequence (TAIR10)
(BLAST)
001: MMESRSPICN TCGEEIGVKS NGEFFVACHE CSFPICKACL EYEFKEGRRI CLRCGNPYDE NVFDDVETKT SKTQSIVPTQ TNNTSQDSGI HARHISTVST
101: IDSELNDEYG NPIWKNRVES WKDKKDKKSK KKKKDPKATK AEQHEAQIPT QQHMEDTPPN TESGATDVLS VVIPIPRTKI TSYRIVIIMR LIILALFFNY
201: RITHPVDSAY GLWLTSVICE IWFAVSWVLD QFPKWSPINR ETYIDRLSAR FEREGEQSQL AAVDFFVSTV DPLKEPPLIT ANTVLSILAL DYPVDKVSCY
301: VSDDGAAMLS FESLVETADF ARKWVPFCKK YSIEPRAPEF YFSLKIDYLR DKVQPSFVKE RRAMKRDYEE FKIRMNALVA KAQKTPEEGW TMQDGTSWPG
401: NNTRDHPGMI QVFLGYSGAR DIEGNELPRL VYVSREKRPG YQHHKKAGAE NALVRVSAVL TNAPFILNLD CDHYVNNSKA VREAMCFLMD PVVGQDVCFV
501: QFPQRFDGID KSDRYANRNI VFFDVNMRGL DGIQGPVYVG TGTVFRRQAL YGYSPPSKPR ILPQSSSSSC CCLTKKKQPQ DPSEIYKDAK REELDAAIFN
601: LGDLDNYDEY DRSMLISQTS FEKTFGLSTV FIESTLMENG GVPDSVNPST LIKEAIHVIS CGYEEKTEWG KEIGWIYGSI TEDILTGFKM HCRGWRSIYC
701: MPLRPAFKGS APINLSDRLH QVLRWALGSV EIFLSRHCPL WYGCSGGRLK LLQRLAYINT IVYPFTSLPL VAYCTLPAIC LLTGKFIIPT LSNLASMLFL
801: GLFISIILTS VLELRWSGVS IEDLWRNEQF WVIGGVSAHL FAVFQGFLKM LAGLDTNFTV TSKTADDLEF GELYIVKWTT LLIPPTSLLI INLVGVVAGF
901: SDALNKGYEA WGPLFGKVFF AFWVILHLYP FLKGLMGRQN RTPTIVILWS ILLASVFSLV WVRINPFVSK TDTTSLSLNC LLIDC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)