AT2G20180.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : phytochrome interacting factor 3-like 5 | ||||||||||||
Curator Summary (TAIR10) |
Encodes a novel Myc-related bHLH transcription factor that has transcriptional activation activity in the dark. It is a key negative regulator of phytochrome-mediated seed germination and acts by inhibiting chlorophyll biosynthesis, light-mediated suppression of hypocotyl elongation and far-red light-mediated suppression of seed germination, and promoting negative gravitropism in hypocotyls. Light reduces this activity in a phy-dependent manner. The protein preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB), is physically associated with APRR1/TOC1 and is degraded in red (R) and far-red (FR) light through the ubiquitin (ub)-26S proteasome pathway to optimize photomorphogenic development in Arabidopsis. It also negatively regulates GA3 oxidase expression. | ||||||||||||
Computational Description (TAIR10) |
phytochrome interacting factor 3-like 5 (PIL5); CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT4G28800.1); Has 4635 Blast hits to 4615 proteins in 348 species: Archae - 0; Bacteria - 26; Metazoa - 878; Fungi - 251; Plants - 3376; Viruses - 2; Other Eukaryotes - 102 (source: NCBI BLink). | ||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:-:8704525..8706237 | ||||||||||||
Molecular Weight (calculated) | 44717.30 Da | ||||||||||||
IEP (calculated) | 7.25 | ||||||||||||
GRAVY (calculated) | -0.83 | ||||||||||||
Length | 407 amino acids | ||||||||||||
Sequence (TAIR10) (BLAST) |
001: MDPQQQPSSD QNLFIQEDEM TSWLHYPLRD DDFCSDLLFS AAPTATATAT VSQVTAARPP VSSTNESRPP VRNFMNFSRL RGDFNNGRGG ESGPLLSKAV 101: VRESTQVSPS ATPSAAASES GLTRRTDGTD SSAVAGGGAY NRKGKAVAMT APAIEITGTS SSVVSKSEIE PEKTNVDDRK RKEREATTTD ETESRSEETK 201: QARVSTTSTK RSRAAEVHNL SERKRRDRIN ERMKALQELI PRCNKSDKAS MLDEAIEYMK SLQLQIQMMS MGCGMMPMMY PGMQQYMPHM AMGMGMNQPI 301: PPPSFMPFPN MLAAQRPLPT QTHMAGSGPQ YPVHASDPSR VFVPNQQYDP TSGQPQYPAG YTDPYQQFRG LHPTQPPQFQ NQATSYPSSS RVSSSKESED 401: HGNHTTG |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)