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AT1G64280.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : regulatory protein (NPR1)
Curator
Summary (TAIR10)
This gene is a key regulator of the salicylic acid (SA)-mediated systemic acquired resistance (SAR) pathway. It is similar to the transcription factor inhibitor I kappa B, and contains ankyrin repeats. It confers resistance to the pathogens Pseudomonas syringae and Peronospora parasitica in a dosage-dependent fashion. Although transgenic Arabidopsis plants overexpressing NPR1 acquire enhanced sensitivity to SA and (benzothiadiazole) BTH, they display no obvious detrimental morphological changes and do not have elevated pathogenesis-related gene expression until activated by inducers or pathogens.
Computational
Description (TAIR10)
NONEXPRESSER OF PR GENES 1 (NPR1); CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), NPR1/NIM1 like, C-terminal (InterPro:IPR021094), BTB/POZ fold (InterPro:IPR011333), Ankyrin repeat-containing domain (InterPro:IPR020683), BTB/POZ-like (InterPro:IPR000210), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: Ankyrin repeat family protein / BTB/POZ domain-containing protein (TAIR:AT4G26120.1); Has 5193 Blast hits to 3365 proteins in 257 species: Archae - 2; Bacteria - 309; Metazoa - 2278; Fungi - 110; Plants - 802; Viruses - 16; Other Eukaryotes - 1676 (source: NCBI BLink).
Protein Annotations
BioGrid:27954DIP:DIP-38585NeggNOG:COG0666eggNOG:KOG0504
EMBL:AC066689EMBL:AY050455EMBL:AY093992EMBL:CP002684
EMBL:U76707EMBL:U87794EnsemblPlants:AT1G64280EnsemblPlants:AT1G64280.1
entrez:842733ExpressionAtlas:P93002Gene3D:1.25.40.20GeneID:842733
Genevisible:P93002GO:GO:0001666GO:GO:0005634GO:GO:0005737
GO:GO:0009408GO:GO:0009611GO:GO:0009617GO:GO:0009625
GO:GO:0009626GO:GO:0009627GO:GO:0009682GO:GO:0009862
GO:GO:0010112GO:GO:0016567GO:GO:0031348GO:GO:0045893
GO:GO:0050832GO:GO:2000022GO:GO:2000031Gramene:AT1G64280.1
hmmpanther:PTHR24198hmmpanther:PTHR24198:SF66HOGENOM:HOG000240298InParanoid:P93002
IntAct:P93002InterPro:IPR000210InterPro:IPR002110InterPro:IPR011333
InterPro:IPR020683InterPro:IPR021094InterPro:IPR024228iPTMnet:P93002
KEGG:ath:AT1G64280KO:K14508ncoils:CoilOMA:NKIMDAD
PaxDb:P93002Pfam:P93002Pfam:PF00651Pfam:PF11900
Pfam:PF12313Pfam:PF12796Pfam:PF13857Pfscan:PS50088
Pfscan:PS50097Pfscan:PS50297PhylomeDB:P93002PIR:F96666
PRIDE:P93002PRO:PR:P93002PROSITE:PS50088PROSITE:PS50097
PROSITE:PS50297ProteinModelPortal:P93002Proteomes:UP000006548RefSeq:NP_176610.1
SMART:SM00225SMART:SM00248SMR:P93002STRING:3702.AT1G64280.1
SUPFAM:SSF48403SUPFAM:SSF54695TAIR:AT1G64280tair10-symbols:ATNPR1
tair10-symbols:NIM1tair10-symbols:NPR1tair10-symbols:SAI1UniGene:At.22448
UniGene:At.72643UniPathway:UPA00143UniProt:B2BDI6UniProt:P93002
Coordinates (TAIR10) chr1:-:23853329..23855407
Molecular Weight (calculated) 66035.50 Da
IEP (calculated) 5.86
GRAVY (calculated) -0.21
Length 593 amino acids
Sequence (TAIR10)
(BLAST)
001: MDTTIDGFAD SYEISSTSFV ATDNTDSSIV YLAAEQVLTG PDVSALQLLS NSFESVFDSP DDFYSDAKLV LSDGREVSFH RCVLSARSSF FKSALAAAKK
101: EKDSNNTAAV KLELKEIAKD YEVGFDSVVT VLAYVYSSRV RPPPKGVSEC ADENCCHVAC RPAVDFMLEV LYLAFIFKIP ELITLYQRHL LDVVDKVVIE
201: DTLVILKLAN ICGKACMKLL DRCKEIIVKS NVDMVSLEKS LPEELVKEII DRRKELGLEV PKVKKHVSNV HKALDSDDIE LVKLLLKEDH TNLDDACALH
301: FAVAYCNVKT ATDLLKLDLA DVNHRNPRGY TVLHVAAMRK EPQLILSLLE KGASASEATL EGRTALMIAK QATMAVECNN IPEQCKHSLK GRLCVEILEQ
401: EDKREQIPRD VPPSFAVAAD ELKMTLLDLE NRVALAQRLF PTEAQAAMEI AEMKGTCEFI VTSLEPDRLT GTKRTSPGVK IAPFRILEEH QSRLKALSKT
501: VELGKRFFPR CSAVLDQIMN CEDLTQLACG EDDTAEKRLQ KKQRYMEIQE TLKKAFSEDN LELGNSSLTD STSSTSKSTG GKRSNRKLSH RRR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)