AT1G61560.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of cotyledons, young leaves and petals, in mature rosette leaves, in anthers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 6 (MLO6); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G11310.1); Has 556 Blast hits to 535 proteins in 58 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 551; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:22708875..22712032 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 67229.70 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 10.06 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.13 | ||||||||||||||||||||||||||||||||||||||||
| Length | 583 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MADQVKEKTL EETSTWAVAV VCFVLLLISI VIEKLIHKIG SWFKKKNKKA LYEALEKVKA ELMLMGFISL LLTIGQGYIS NICIPKNIAA SMHPCSASEE 101: ARKYGKKDVP KEDEEENLRR KLLQLVDSLI PRRSLATKGY DKCAEKGKVA FVSAYGMHQL HIFIFVLAVC HVIYCIVTYA LGKTKMRRWK KWEEETKTIE 201: YQYSHDPERF RFARDTSFGR RHLSFWSKST ITLWIVCFFR QFFRSVTKVD YLTLRHGFIM AHLAPGSDAR FDFRKYIQRS LEEDFKTIVE INPVIWFIAV 301: LFLLTNTNGL NSYLWLPFIP FIVILIVGTK LQVIITKLGL RIQEKGDVVK GTPLVQPGDH FFWFGRPRFI LFLIHLVLFT NAFQLAFFVW STYEFGLKNC 401: FHESRVDVII RISIGLLVQI LCSYVTLPLY ALVTQMGSKM KPTVFNERVA TALKSWHHTA KKNIKHGRTS ESTTPFSSRP TTPTHGSSPI HLLRNAPHKR 501: SRSVDESFAN SFSPRNSDFD SWDPESQHET AETSNSNHRS RFGEEESEKK FVSSSVELPP GPGQIRTQHE ISTISLRDFS FKR |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)