AT1G11000.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO4 belongs to the clade I, with AtMLO11 and AtMLO14. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of root, cotyledons and young leaves, it was not expressed in mature rosette leaves, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 4 (MLO4); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G53760.2); Has 528 Blast hits to 517 proteins in 50 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 522; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:-:3671935..3675909 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 65469.30 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.23 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.05 | ||||||||||||||||||||||||||||||||||||||||
| Length | 573 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MEHMMKEGRS LAETPTYSVA SVVTVLVFVC FLVERAIYRF GKWLKKTRRK ALFTSLEKMK EELMLLGLIS LLLSQSARWI SEICVNSSLF NSKFYICSEE 101: DYGIHKKVLL EHTSSTNQSS LPHHGIHEAS HQCGHGREPF VSYEGLEQLL RFLFVLGITH VLYSGIAIGL AMSKIYSWRK WEAQAIIMAE SDIHAKKTKV 201: MKRQSTFVFH HASHPWSNNR FLIWMLCFLR QFRGSIRKSD YFALRLGFLT KHNLPFTYNF HMYMVRTMED EFHGIVGISW PLWVYAIVCI CINVHGLNMY 301: FWISFVPAIL VMLVGTKLEH VVSKLALEVK EQQTGTSNGA QVKPRDGLFW FGKPEILLRL IQFIIFQNAF EMATFIWFLW GIKERSCFMK NHVMISSRLI 401: SGVLVQFWCS YGTVPLNVIV TQMGSRHKKA VIAESVRDSL HSWCKRVKER SKHTRSVCSL DTATIDERDE MTVGTLSRSS SMTSLNQITI NSIDQAESIF 501: GAAASSSSPQ DGYTSRVEEY LSETYNNIGS IPPLNDEIEI EIEGEEDNGG RGSGSDENNG DAGETLLELF RRT |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)