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AT5G13300.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.730
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : ARF GTPase-activating protein
Curator
Summary (TAIR10)
Belongs to 15-member small GTPase gene family, ARF-GAP domain proteins (AGD); corresponds to AGD3, and is one of four proteins belonging to class 1, together with AGD1, AGD2 and AGD4. The protein contains four domains: BAR domain, PH domain, an ARF-GAP domain, and two Ankyrin repeats. In sfc mutants, the secondary and tertiary veins of cotyledons, leaves, sepals and petals are largely replaced by small segments of discontinuous veins. sfc mutants have exaggerated responses to auxin.
Computational
Description (TAIR10)
SCARFACE (SFC); FUNCTIONS IN: ARF GTPase activator activity, phosphoinositide binding; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, phloem or xylem histogenesis, leaf morphogenesis; LOCATED IN: cytosol, trans-Golgi network transport vesicle, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164), Pleckstrin homology-type (InterPro:IPR011993), Ankyrin repeat-containing domain (InterPro:IPR020683), BAR (InterPro:IPR004148), Pleckstrin homology (InterPro:IPR001849), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 1 (TAIR:AT5G61980.1); Has 64753 Blast hits to 27558 proteins in 1221 species: Archae - 110; Bacteria - 5131; Metazoa - 34265; Fungi - 4887; Plants - 2591; Viruses - 654; Other Eukaryotes - 17115 (source: NCBI BLink).
Protein Annotations
BioGrid:16449eggNOG:COG5347eggNOG:KOG0521EMBL:AB194395
EMBL:AK229433EMBL:AL163491EMBL:CP002688EnsemblPlants:AT5G13300
EnsemblPlants:AT5G13300.1entrez:831171Gene3D:1.20.1270.60Gene3D:1.25.40.20
Gene3D:2.30.29.30GeneID:831171Genevisible:Q5W7F2GO:GO:0005096
GO:GO:0005829GO:GO:0005886GO:GO:0006897GO:GO:0009733
GO:GO:0009965GO:GO:0010051GO:GO:0010087GO:GO:0030140
GO:GO:0035091GO:GO:0043547GO:GO:0046872Gramene:AT5G13300.1
hmmpanther:PTHR23180hmmpanther:PTHR23180:SF284HOGENOM:HOG000006421InParanoid:Q5W7F2
IntAct:Q5W7F2InterPro:IPR001164InterPro:IPR001849InterPro:IPR002110
InterPro:IPR004148InterPro:IPR011993InterPro:IPR020683InterPro:IPR027267
iPTMnet:Q5W7F2KEGG:ath:AT5G13300KO:K12489ncoils:Coil
OMA:RCFDRGTPaxDb:Q5W7F2Pfam:PF00169Pfam:PF01412
Pfam:PF13637Pfam:PF16746Pfam:Q5W7F2Pfscan:PS50003
Pfscan:PS50088Pfscan:PS50115Pfscan:PS50297PhylomeDB:Q5W7F2
PIR:T48577PRIDE:Q5W7F2PRINTS:PR00405PRO:PR:Q5W7F2
PROSITE:PS50003PROSITE:PS50088PROSITE:PS50115PROSITE:PS50297
ProteinModelPortal:Q5W7F2Proteomes:UP000006548RefSeq:NP_196834.3SMART:SM00105
SMART:SM00233SMART:SM00248SMART:SM00721SMR:Q5W7F2
STRING:3702.AT5G13300.1SUPFAM:SSF103657SUPFAM:SSF48403SUPFAM:SSF50729
SUPFAM:SSF57863TAIR:AT5G13300tair10-symbols:AGD3tair10-symbols:SFC
tair10-symbols:VAN3UniGene:At.32090UniProt:Q5W7F2
Coordinates (TAIR10) chr5:-:4255923..4262018
Molecular Weight (calculated) 92529.30 Da
IEP (calculated) 8.20
GRAVY (calculated) -0.53
Length 827 amino acids
Sequence (TAIR10)
(BLAST)
001: MHFTKLDDSP MFRKQLQSME ESAEILRERS LKFYKGCRKY TEGLGEAYDG DIAFASALET FGGGHNDPIS VAFGGPVMTK FTIALREIGT YKEVLRSQVE
101: HILNDRLLQF ANMDLHEVKE ARKRFDKASL TYDQAREKFL SLRKGTKSDV AAALEQELHT SRSMFEQARF NLVTALSNVE AKKRFEFLEA VSGTMDAHLR
201: YFKQGYELLH QMEPYINQVL TYAQQSRERS NYEQAALNEK MQEYKRQVDR ESRWGSNGSN GSPNGDGIQA IGRSSHKMID AVMQSAARGK VQTIRQGYLS
301: KRSSNLRGDW KRRFFVLDSR GMLYYYRKQC SKPSGSGSQL SGQRNSSELG SGLLSRWLSS NNHGHGGVHD EKSVARHTVN LLTSTIKVDA DQSDLRFCFR
401: IISPTKNYTL QAESALDQMD WIEKITGVIA SLLSSQVPEQ RLPGSPMGSG HHRSASESSS YESSEYDHPT TEEFVCERSF LGYNERPSRS FQPQRSIRKG
501: EKPIDALRKV CGNDKCADCG APEPDWASLN LGVLVCIECS GVHRNLGVHI SKVRSLTLDV KVWEPSVISL FQALGNTFAN TVWEELLHSR SAIHFDPGLT
601: VSDKSRVMVT GKPSYADMIS IKEKYIQAKY AEKLFVRRSR DSDFPQSAAQ QMWDAVSGND KKAVYRLIVN GDADVNYVYD QTSSSSLTLS RVILVPERPK
701: REDVLLRLRN ELLDRTGSSS NISPEGSGGS SLLHCACEKA DLGMVELLLQ YGANVNASDS SGQTPLHCCL LRGKVTIARL LLTRGADPEA MNREGKTALD
801: IAAESNFTDP EVLALLSDTN GYNHRQC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)