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AT3G63300.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : FORKED 1
Curator
Summary (TAIR10)
Encodes a pleckstrin homology domain- and DUF828-containing protein. Mutants have defects in leaf vascular pattering, with vascular bundles that fail to meet distally in both the cotyledons and leaves. Necessary to the formation of the closed leaf vascular pattern characteristic of dicot leaves in response to auxin. Redundant with FKD2. FKD1 may influence PIN1 localization in an auxin dependent manner. proposed to be a key component of the auxin canalization pathway.
Computational
Description (TAIR10)
FORKED 1 (FKD1); CONTAINS InterPro DOMAIN/s: Pleckstrin-like, plant (InterPro:IPR013666), Protein of unknown function DUF828 (InterPro:IPR008546); BEST Arabidopsis thaliana protein match is: Plant protein of unknown function (DUF828) with plant pleckstrin homology-like region (TAIR:AT3G22810.1); Has 742 Blast hits to 348 proteins in 78 species: Archae - 0; Bacteria - 118; Metazoa - 127; Fungi - 51; Plants - 226; Viruses - 0; Other Eukaryotes - 220 (source: NCBI BLink).
Protein Annotations
eggNOG:ENOG410IIUGeggNOG:ENOG4111DWTEMBL:AL138648EMBL:AY062506
EMBL:BT002092EMBL:CP002686EnsemblPlants:AT3G63300EnsemblPlants:AT3G63300.1
entrez:825505ExpressionAtlas:Q8W4K5GeneID:825505Genevisible:Q8W4K5
GO:GO:0009733GO:GO:0009734GO:GO:0010087GO:GO:0010305
hmmpanther:PTHR31351hmmpanther:PTHR31351:SF4HOGENOM:HOG000237680InParanoid:Q8W4K5
IntAct:Q8W4K5InterPro:IPR008546InterPro:IPR013666KEGG:ath:AT3G63300
OMA:FLGVCNQPaxDb:Q8W4K5Pfam:PF05703Pfam:PF08458
PhylomeDB:Q8W4K5PIR:T48119PRIDE:Q8W4K5PRO:PR:Q8W4K5
ProteinModelPortal:Q8W4K5Proteomes:UP000006548RefSeq:NP_191889.2STRING:3702.AT3G63300.1
TAIR:AT3G63300tair10-symbols:FKD1UniGene:At.27321UniProt:Q8W4K5
Coordinates (TAIR10) chr3:+:23385033..23387625
Molecular Weight (calculated) 53338.10 Da
IEP (calculated) 9.78
GRAVY (calculated) -0.41
Length 498 amino acids
Sequence (TAIR10)
(BLAST)
001: MERELRRPNP INSSRRPEIF SSGGSSTQLP ESPRGPMEFL SRSWSVSALE VSRALHTAKS ASATNRPPSS INTPIPEETL NPEKEECPPE NSTSVSSQFS
101: FAASATSQLV LERIMSQSEV SPLTSGRLSH SSGPLNGGGS FTETDSPPIS PSDEFDDVIK YFRTHNTIHP LFSGTGGSRG TTGNGSNTPM AGTGPKTVGR
201: WLKDRKEKKK EETRTQNAQV HAAVSVAAVA SAVAAVAAAT AASSPGKNEQ MARIDMAMAS AAALVAAQCV EAAEIMGADR DHLTSVVSSA VNVKSHDDIV
301: TLTAAAATAL RGAATLKARA LKEVWNIAAV LPAEKGASSA LCGQVDTKHS DSSFSGELPV AGEDFLGVCN QELLAKGTEL LKRTRGGELH WKIVSVYINK
401: AGQAVLKMKS KHVGGTFTKK KKHMVLEVRK DIPAWAGRDL FNGDKHHYFG LKTETKRVIE FECRNQREYE IWTQGVSRLL AIAAEKKQKS SMSKWMAP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)