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AT4G38430.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:22522809 (2012): cytosol cytosolic ribosomes
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : rho guanyl-nucleotide exchange factor 1
Curator
Summary (TAIR10)
Member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily, also known as DUF315). Interacts with ROP1 but the whole protein lacks Rho guanyl-nucleotide exchange factor activity in vitro. The DUF315/PRONE domain is sufficient to confer RopGEF catalytic activity.
Computational
Description (TAIR10)
rho guanyl-nucleotide exchange factor 1 (ROPGEF1); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 7 (TAIR:AT5G02010.1); Has 308 Blast hits to 304 proteins in 16 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 308; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
Protein Annotations
BioGrid:15280DIP:DIP-59393NeggNOG:ENOG410IGJ8eggNOG:ENOG4110DIX
EMBL:AL035539EMBL:AL161593EMBL:AY056193EMBL:AY056375
EMBL:AY084995EMBL:AY133649EMBL:BT000462EMBL:BT000975
EMBL:CP002687EnsemblPlants:AT4G38430EnsemblPlants:AT4G38430.1entrez:830000
GeneID:830000Genevisible:Q93ZY2GO:GO:0005089GO:GO:0005829
GO:GO:0009860GO:GO:0016324GO:GO:0043547GO:GO:0080092
Gramene:AT4G38430.1hmmpanther:PTHR33101hmmpanther:PTHR33101:SF6HOGENOM:HOG000238290
InParanoid:Q93ZY2IntAct:Q93ZY2InterPro:IPR005512KEGG:ath:AT4G38430
MINT:MINT-8342686OMA:MAFNITAPaxDb:Q93ZY2Pfam:PF03759
Pfam:Q93ZY2Pfscan:PS51334PhylomeDB:Q93ZY2PIR:T05671
PRIDE:Q93ZY2PRO:PR:Q93ZY2PROSITE:PS51334ProteinModelPortal:Q93ZY2
Proteomes:UP000006548RefSeq:NP_195556.1SMR:Q93ZY2STRING:3702.AT4G38430.1
TAIR:AT4G38430tair10-symbols:ATROPGEF1tair10-symbols:ROPGEF1UniGene:At.2769
UniProt:Q93ZY2
Coordinates (TAIR10) chr4:+:17986643..17988659
Molecular Weight (calculated) 60851.20 Da
IEP (calculated) 5.23
GRAVY (calculated) -0.40
Length 548 amino acids
Sequence (TAIR10)
(BLAST)
001: MGSLSSEEDD EVSSERCGSY SPSADISESE SSSSFSCHRF DGEGASSSIP SSPRVVAGRG FYFPAPVMLP VIGGKDVVWD DKQPDNDLSE IEMMKERFAK
101: LLLGEDMSGG GKGVCTALAI SNAITNLSAT VFGELWRLEP LAPQKKAMWR RELEWLLCVS DSIVELIPSI QQFPGGGTYE IMETRPRSDL YANLPALKKL
201: DAMLIDMLDA FSDTEFWYTD RGIVLGDCDK DSYNSPASVR QEDKWWLPCP KVPPNGLSEE ARKKLQQCRD FANQILKAAL AINSGVLAEM EIPDPYLETL
301: PKSGKECLGE IIYQYLTANK FSPECLLDCL DLSSEHQTLE IANRIEAAVH VWRQKNGRRH KKQAKLKLSS WGGKVKGLVN DNERNDFLVQ RAETLLQSLR
401: IRFPGLPQTT LDMNKIQYNK DVGQSILESY SRVMESMAFN ITARIDDVLY VDDAMRRSIS VTESLSLFSI NGLNPQKAFS VQSSPHGSPF ATPALSVASR
501: SPRRAPPLYS VKRNGTREKG IVGETEKAWS YAGNLSSRRV TGVTPERD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)