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AT3G63530.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : RING/U-box superfamily protein
Curator
Summary (TAIR10)
Encodes a novel E3 ubiquitin ligase that acts as a central negative regulator of Arabidopsis floral organ size. Organ size is limited by restricting the period of proliferative growth, rather than the rate of growth and appears to act in a novel pathway, independent of ANT and JAG. Both mRNA and protein are expressed in all actively growing regions of the plant and the vasculature and the protein is rapidly turned over by proteasome-mediated degradation.
Computational
Description (TAIR10)
BIG BROTHER (BB); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT3G19910.1); Has 8059 Blast hits to 8045 proteins in 262 species: Archae - 0; Bacteria - 0; Metazoa - 2322; Fungi - 418; Plants - 4266; Viruses - 8; Other Eukaryotes - 1045 (source: NCBI BLink).
Protein Annotations
EC:6.3.2.-eggNOG:ENOG41121N2eggNOG:KOG0800EMBL:AK227673
EMBL:AK318710EMBL:AL732522EMBL:BT010197EMBL:CP002686
EnsemblPlants:AT3G63530EnsemblPlants:AT3G63530.1EnsemblPlants:AT3G63530.2entrez:825528
Gene3D:3.30.40.10GeneID:825528GO:GO:0004842GO:GO:0008270
GO:GO:0016567GO:GO:0016874GO:GO:0031624GO:GO:0046621
GO:GO:0048437GO:GO:0051865hmmpanther:PTHR14155hmmpanther:PTHR14155:SF75
HOGENOM:HOG000239779InParanoid:Q8L649InterPro:IPR001841InterPro:IPR013083
InterPro:IPR033276KEGG:ath:AT3G63530KO:K19045OMA:WQDDIDP
PANTHER:PTHR14155:SF75PaxDb:Q8L649Pfam:PF13639Pfam:Q8L649
Pfscan:PS50089PhylomeDB:Q8L649PRO:PR:Q8L649PROSITE:PS50089
ProteinModelPortal:Q8L649Proteomes:UP000006548RefSeq:NP_001030922.1RefSeq:NP_680148.1
SMART:SM00184SMR:Q8L649STRING:3702.AT3G63530.1SUPFAM:SSF57850
TAIR:AT3G63530tair10-symbols:BBtair10-symbols:BB2UniGene:At.44049
UniPathway:UPA00143UniProt:Q8L649
Coordinates (TAIR10) chr3:-:23456407..23457787
Molecular Weight (calculated) 27984.20 Da
IEP (calculated) 4.47
GRAVY (calculated) -0.70
Length 248 amino acids
Sequence (TAIR10)
(BLAST)
001: MNGDNRPVED AHYTETGFPY AATGSYMDFY GGAAQGPLNY DHAATMHPQD NLYWTMNTNA YKFGFSGSDN ASFYGSYDMN DHLSRMSIGR TNWDYHPMVN
101: VADDPENTVA RSVQIGDTDE HSEAEECIAN EHDPDSPQVS WQDDIDPDTM TYEELVELGE AVGTESRGLS QELIETLPTK KYKFGSIFSR KRAGERCVIC
201: QLKYKIGERQ MNLPCKHVYH SECISKWLSI NKVCPVCNSE VFGEPSIH
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)