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AT4G12620.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : origin of replication complex 1B
Curator
Summary (TAIR10)
Origin Recognition Complex subunit 1b. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors. Interacts with ORC2 and ORC5. Highly expressed in proliferating cells. Expression levels are independent of light regime.
Computational
Description (TAIR10)
origin of replication complex 1B (ORC1B); CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Origin recognition complex, subunit 1 (InterPro:IPR020793), ATPase, AAA+ type, core (InterPro:IPR003593), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: origin recognition complex 1 (TAIR:AT4G14700.1); Has 5914 Blast hits to 5512 proteins in 383 species: Archae - 477; Bacteria - 4; Metazoa - 3209; Fungi - 806; Plants - 927; Viruses - 0; Other Eukaryotes - 491 (source: NCBI BLink).
Protein Annotations
DIP:DIP-46671NeggNOG:COG1474eggNOG:KOG1514EMBL:AJ426477
EMBL:AL049730EMBL:AL161534EMBL:CP002687EnsemblPlants:AT4G12620
EnsemblPlants:AT4G12620.1entrez:826875Gene3D:3.30.40.10Gene3D:3.40.50.300
GeneID:826875Genevisible:Q9SU24GO:GO:0000808GO:GO:0003682
GO:GO:0005524GO:GO:0005634GO:GO:0006260GO:GO:0006351
GO:GO:0006355GO:GO:0008270GO:GO:0009567GO:GO:0010385
Gramene:AT4G12620.1hmmpanther:PTHR10763hmmpanther:PTHR10763:SF23HOGENOM:HOG000030288
InParanoid:Q9SU24IntAct:Q9SU24InterPro:IPR001025InterPro:IPR001965
InterPro:IPR003593InterPro:IPR003959InterPro:IPR011011InterPro:IPR013083
InterPro:IPR019786InterPro:IPR019787InterPro:IPR027417iPTMnet:Q9SU24
KEGG:ath:AT4G12620KO:K02603MINT:MINT-7303885OMA:EMECILR
PaxDb:Q9SU24PDB:5HH7PDBsum:5HH7Pfam:PF00004
Pfam:PF00628Pfam:PF01426Pfam:Q9SU24Pfscan:PS50016
Pfscan:PS51038PhylomeDB:Q9SU24PIR:E85135PRIDE:Q9SU24
PRO:PR:Q9SU24PROSITE:PS01359PROSITE:PS50016PROSITE:PS51038
ProteinModelPortal:Q9SU24Proteomes:UP000006548Reactome:R-ATH-113510Reactome:R-ATH-68616
Reactome:R-ATH-68689Reactome:R-ATH-68867Reactome:R-ATH-68949Reactome:R-ATH-68962
Reactome:R-ATH-69205Reactome:R-ATH-69298RefSeq:NP_192999.1scanprosite:PS01359
SMART:SM00249SMART:SM00382SMART:SM00439SMR:Q9SU24
STRING:3702.AT4G12620.1SUPFAM:SSF52540SUPFAM:SSF57903TAIR:AT4G12620
tair10-symbols:ATORC1Btair10-symbols:ORC1Btair10-symbols:UNE13UniGene:At.48852
UniProt:Q9SU24
Coordinates (TAIR10) chr4:-:7459812..7462253
Molecular Weight (calculated) 92174.50 Da
IEP (calculated) 7.52
GRAVY (calculated) -0.56
Length 813 amino acids
Sequence (TAIR10)
(BLAST)
001: MASTPRAKTF KSPTKTPSNI YRKSYLSPSS TSHTPQTPET HTPLRRSARH VSRKIDLGND PIDAPGNDPI EGMNLIRKRE RAPRKPTTDV VPSKSKKTET
101: PKKKKKIDSF TPVSPIRSET IKKTKKKKRV YYNKVEFDET EFEIGDDVYV KRREDSNSDE EEDPEIEDCQ ICFKSDTNIM IECDDCLGGF HLKCLKPPLK
201: EVPEGDWICQ FCEVKKSGQS QTLDLPKPPE GKKLARTMRE KLLSGDLWAA RIDKLWKEVD DGVYWIRARW YMIPEETVSG RQPHNLKREL YLTNDFADIE
301: MECILRHCSV KCPKEFSKAS NDGDDVFLCE YEYDVHWRSF KRLAELADGD SDSDQEWNGR KEEEVDDSDE EMELDDEVLK SKRGGLTSAR GGANSRKGRF
401: FGVEKVGMKL IPEHVRCHKQ SELEKAKATL LLATRPKSLP CRSKEMEEIT SFIKGSISDD QCLGRCMYIH GVPGTGKTIS VLSVMKNLKA EVEEGSVSPY
501: CFVEINGLKL ASPENIYSVI YEALSGHRVG WKKALQCLNE RFAEGKRIGK EDEKPCILLI DELDLLVTRN QSVLYNILDW PTKPNSKLVV LGIANTMDLP
601: EKLLPRISSR MGIQRLCFGP YNHTQLQEII STRLNGIDAF EKTAIEFASR KVAAISGDAR RALEICRRAA EVADHRLNTN KSAKNQLVIM ADVEAAIQEM
701: FQAPHIQVMK SVSKLSKIFL TAMVHELYKT GMAETTFDRV ATTVSSICLT NGEAFPGWDI LLKIGCDLGE CRIILCEPGE KHRLQKLQLN FPSDDVAFAL
801: KDNKDLPWLA NYL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)