AT2G07690.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : Minichromosome maintenance (MCM2/3/5) family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
MINICHROMOSOME MAINTENANCE 5 (MCM5); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin, nucleus, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 5 (InterPro:IPR008048); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 3980 Blast hits to 3841 proteins in 547 species: Archae - 376; Bacteria - 145; Metazoa - 1209; Fungi - 933; Plants - 431; Viruses - 3; Other Eukaryotes - 883 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:-:3523379..3527388 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 81019.10 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 7.50 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 727 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MSGWDEGAVY YSDQPQFPEA GDAATISPHA VLTKFKEFIR NFEIEQNCFP YREALLDNPK RLVVHLEDLL SFDSDLPSLI RSAPADYLPV FEKAAGEVLT 101: GLKMREANEG GVMEEPLTRD VQILLTSRED PVSMRLLGAQ YISKLVKISG ISIAASRVKA KATYVFLVCK NCKKTREVPC RPGLGGAIVP RSCDNIPQPG 201: EEPCPLDPWM VVPDRSQYVD QQTLKLQENP EDVPTGELPR NMLLSVDRHL VQTIVPGTRL TVMGIYSIFQ ASSSSNSHKG AVAIRQPYIR VVGLEDTNEA 301: SSRGPANFTP DEEEEFKKFA DSQDVYKNIC TKIAPSIFGH EDVKRAAACL LFGGSRKSLP DGVKLRGDIN VLLLGDPSTA KSQFLKFVEK TAPIAVYTSG 401: KGSSAAGLTA SVIRDSSTRE FYLEGGAMVL ADGGVVCIDE FDKMRPEDRV AIHEAMEQQT ISIAKAGITT VLNSRTSVLA AANPPSGRYD DLKTAQDNID 501: LQTTILSRFD LIFIVKDIRK YSQDKEIASH IIRVHASANK FSDENTDSKE DNWLKRYIQY CRARCHPRLS KDAAENLQRK YVTIRMDMKR RAHETGEAAP 601: IPITVRQLEA IVRLSESLAK MRLSHEATPD DVDKAFKLFD TSTMDAARSG INQQINITGE MANEIKQAET QIKRRMGIGA RLSERRLIED LARMGMNDSM 701: VRRALLIMHQ RGEVEYQRER RSIVRKA |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)