AT2G17430.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 ASURE: plasma membrane What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Seven transmembrane MLO family protein | ||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO7 belongs to the clade III, with AtMLO5, AtMLO8, AtMLO9, and AtMLO10. The gene is expressed in vegetative organs (RT-PCR experiments)and in pollen grains, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). | ||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
MILDEW RESISTANCE LOCUS O 7 (MLO7); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: seedling growth, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT5G65970.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:7568018..7570758 | ||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 62115.30 Da | ||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 9.67 | ||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.16 | ||||||||||||||||||||||||||||||||||||||||||||
| Length | 542 amino acids | ||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MITRSRCRRS LLWFLVFHGG ATATGAPSGG KELSQTPTWA VAVVCTFLIL ISHLLEKGLQ RLANWLWKKH KNSLLEALEK IKAELMILGF ISLLLTFGEP 101: YILKICVPRK AALSMLPCLS EDTVLFQKLA PSSLSRHLLA AGDTSINCKQ GSEPLITLKG LHQLHILLFF LAIFHIVYSL ITMMLSRLKI RGWKKWEQET 201: LSNDYEFSID HSRLRLTHET SFVREHTSFW TTTPFFFYVG CFFRQFFVSV ERTDYLTLRH GFISAHLAPG RKFNFQRYIK RSLEDDFKLV VGISPVLWAS 301: FVIFLLFNVN GWRTLFWASI PPLLIILAVG TKLQAIMATM ALEIVETHAV VQGMPLVQGS DRYFWFDCPQ LLLHLIHFAL FQNAFQITHF FWIWYSFGLK 401: SCFHKDFNLV VSKLFLCLGA LILCSYITLP LYALVTQMGS HMKKAVFDEQ MAKALKKWHK DIKLKKGKAR KLPSKTLGVS ESFSLSSSSS ATTLHRSKTT 501: GHSSNIIYYK QEDEEDEMSD LEAGAEDAID RIQQQEMQFH NS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)