AT2G02560.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.999 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : cullin-associated and neddylation dissociated | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Arabidopsis thaliana homolog of human CAND1 (cullin-associated and neddylation-dissociated). Putative similarity to TBP-interacting protein TIP120. Ubiquitously expressed in plant tissues throughout development. T-DNA insertion mutant plants were completely sterile and resistant to sirtinol and auxin, but not to gibberellins or brassinolide. Displayed developmental phenotypes similar to those of axr1, namely, short petioles, downwardly curling leaves, shorter inflorescence. Required for SCF function and appears to modulate SCF complex cycling. Physically interacts with CUL1. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
cullin-associated and neddylation dissociated (CAND1); FUNCTIONS IN: binding; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, vegetative to reproductive phase transition of meristem; LOCATED IN: cell wall, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), TATA-binding protein interacting (TIP20) (InterPro:IPR013932); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr2:+:690345..697342 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 134905.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 5.98 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.00 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1219 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MANLQVSGIL EKFQMTGKDK DYRYMATSDL LNELNKDSFK IDLDLEVRLS SIILQQLDDV AGDVSGLAVK CLAPLVKKVG EERIVEMTNK LCDKLLHGKD 0101: QHRDTASIAL RTVVAQIAPT LAPSILVTLT PQMIGGISGQ GMSSGIKCEC LEIMCDVVQK YGSLMTDDHE KLLNTLLLQL GCNQATVRKK TVTCIASLAS 0201: SLSDDLLAKA TVEVVKNLSN RNAKSEITRT NIQMIGALCR AVGYRFGTHL GNTVPVLINY CTSASENDEE LREYSLQALE SFLLRCPRDI SPYCDEILNL 0301: TLEYISYDPN FTDNMEEDTD NETLEDEEDD ESANEYTDDE DASWKVRRAA AKCLAGLIVS RSEMLTKVYQ EACPKLIDRF KEREENVKMD VFNTFIDLLR 0401: QTGNVTKGQT DTDESSPKWL LKQEVSKIVK SINRQLREKS VKTKVGAFSV LRELVVVLPD CLADHIGSLV PGIERALNDK SSTSNLKIEA LVFTKLVLAS 0501: HAPPVFHPYI KALSSPVLAA VGERYYKVTA EALRVCGELV RVVRPSTAGM GFDFKPFVHP IYNAIMSRLT NQDQDQEVKE CAITCMGLVI STFGDQLRAE 0601: LPSCLPVLVD RMGNEITRLT AVKAFSVIAT SPLHINLSCV LDHLIAELTG FLRKANRVLR QATLITMNTL VTAYGDKIGS EAYEVILVEL SSLISVSDLH 0701: MTALALELCC TLMTGKSCSE NISLAVRNKV LPQALTLVKS PLLQGQALLD LQKFFEALVY HANTSFYTLL ESLLSCAKPS PQSGGVPKQA LYSIAQCVAV 0801: LCLAAGDKNC SSTVKMLMEI LKDDSGTNSA KQHLALLSLG EIGRRKDLSA HAGIETIVIE SFQSPFEEIK SAASYALGNI AVGNLSNYLP FILDQIDNQQ 0901: KKQYILLHSL KEVIVRQSVD KADFQNSSVE KILALLFNHC ESEEEGVRNV VAECLGKMAL IEPEKLVPAL QVRTTSPAAF TRATVVTAVK YSVVERPEKL 1001: DEIIFPQISS FLMLIKDGDR HVRRAAVSAL STFAHYKPNL IKGLLPELLP LLYDQTVIKK ELIRTVDLGP FKHVVDDGLE LRKAAFECVF TLVDSCLDQV 1101: NPSSFIVPFL KSGLEDHYDL KMLCHLILSL LADKCPSAVL AVLDSLVEPL HKTISFKPKQ DAVKQEHDRN EDMIRSALRA ISSLDRINGV DYSHKFKGLM 1201: GDMKRSVPLW EKFQTIRNE |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)