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AT4G21670.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data
Description (TAIR10) protein_coding : C-terminal domain phosphatase-like 1
Curator
Summary (TAIR10)
encodes a a novel transcriptional repressor harboring two double-stranded RNA-binding domains and a region homologous to the catalytic domain of RNA polymerase II C-terminal domain phosphatases found in yeast and in animals that regulate gene transcription. Protein exhibits innate phosphatase activity in vitro. Mutants exhibit hyperresponsiveness to ABA, cold, and NaCl.
Computational
Description (TAIR10)
C-terminal domain phosphatase-like 1 (CPL1); FUNCTIONS IN: double-stranded RNA binding, phosphatase activity, nucleotide phosphatase activity; INVOLVED IN: abscisic acid mediated signaling pathway, negative regulation of transcription, response to abiotic stimulus; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: Double-stranded RNA-binding (InterPro:IPR001159), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: carboxyl-terminal domain (ctd) phosphatase-like 2 (TAIR:AT5G01270.2); Has 330 Blast hits to 317 proteins in 105 species: Archae - 0; Bacteria - 31; Metazoa - 57; Fungi - 81; Plants - 112; Viruses - 1; Other Eukaryotes - 48 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G21670-MONOMERBioGrid:13543EC:3.1.3.16eggNOG:COG5190eggNOG:KOG0323EMBL:AK221944EMBL:AK229289
EMBL:AL035527EMBL:AL161555EMBL:AY557186EMBL:CP002687EnsemblPlants:AT4G21670EnsemblPlants:AT4G21670.1entrez:828254
Gene3D:3.30.160.20Gene3D:3.40.50.1000GeneID:828254GO:GO:0003723GO:GO:0004647GO:GO:0004721GO:GO:0005634
GO:GO:0006351GO:GO:0007275GO:GO:0008420GO:GO:0009611GO:GO:0009651GO:GO:0009738GO:GO:0016591
GO:GO:0016791GO:GO:0045892GO:GO:0046872GO:GO:0070940Gramene:AT4G21670.1hmmpanther:PTHR23081hmmpanther:PTHR23081:SF7
HOGENOM:HOG000078695InParanoid:Q5YDB6IntAct:Q5YDB6InterPro:IPR004274InterPro:IPR014720InterPro:IPR023214iPTMnet:Q5YDB6
KEGG:ath:AT4G21670KO:K18998ncoils:CoilOMA:KKQPPHPPaxDb:Q5YDB6Pfam:PF00035Pfam:PF03031
Pfam:Q5YDB6Pfscan:PS50137Pfscan:PS50969PhylomeDB:Q5YDB6PIR:T05842PRIDE:Q5YDB6PRO:PR:Q5YDB6
PROSITE:PS50137PROSITE:PS50969ProteinModelPortal:Q5YDB6Proteomes:UP000006548RefSeq:NP_193898.3SMART:SM00358SMART:SM00577
STRING:3702.AT4G21670.1SUPFAM:SSF54768SUPFAM:SSF56784TAIR:AT4G21670tair10-symbols:ATCPL1tair10-symbols:CPL1tair10-symbols:FRY2
UniGene:At.2700UniGene:At.32611UniProt:Q5YDB6
Coordinates (TAIR10) chr4:+:11511511..11516922
Molecular Weight (calculated) 108427.00 Da
IEP (calculated) 6.08
GRAVY (calculated) -0.53
Length 967 amino acids
Sequence (TAIR10)
(BLAST)
001: MYSNNRVEVF HGDGRLGELE IYPSRELNQQ QDDVMKQRKK KQREVMELAK MGIRISHFSQ SGERCPPLAI LTTISSCGLC FKLEASPSPA QESLSLFYSS
101: CLRDNKTAVM LLGGEELHLV AMYSENIKND RPCFWAFSVA PGIYDSCLVM LNLRCLGIVF DLDETLVVAN TMRSFEDKID GFQRRINNEM DPQRLAVIVA
201: EMKRYQDDKN LLKQYIESDQ VVENGEVIKV QSEIVPALSD NHQPLVRPLI RLQEKNIILT RINPMIRDTS VLVRMRPSWE ELRSYLTAKG RKRFEVYVCT
301: MAERDYALEM WRLLDPEGNL INTNDLLARI VCVKSGFKKS LFNVFLDGTC HPKMALVIDD RLKVWDEKDQ PRVHVVPAFA PYYSPQAEAA ATPVLCVARN
401: VACGVRGGFF RDFDDSLLPR IAEISYENDA EDIPSPPDVS HYLVSEDDTS GLNGNKDPLS FDGMADTEVE RRLKEAISAS SAVLPAANID PRIAAPVQFP
501: MASASSVSVP VPVQVVQQAI QPSAMAFPSI PFQQPQQPTS IAKHLVPSEP SLQSSPAREE GEVPESELDP DTRRRLLILQ HGQDTRDPAP SEPSFPQRPP
601: VQAPPSHVQS RNGWFPVEEE MDPAQIRRAV SKEYPLDSEM IHMEKHRPRH PSFFSKIDNS TQSDRMLHEN RRPPKESLRR DEQLRSNNNL PDSHPFYGED
701: ASWNQSSSRN SDLDFLPERS VSATETSADV LHGIAIKCGA KVEYKPSLVS STDLRFSVEA WLSNQKIGEG IGKSRREALH KAAEASIQNL ADGYMRANGD
801: PGPSHRDATP FTNENISMGN ANALNNQPFA RDETALPVSS RPTDPRLEGS MRHTGSITAL RELCASEGLE MAFQSQRQLP SDMVHRDELH AQVEIDGRVV
901: GEGVGSTWDE ARMQAAERAL SSVRSMLGQP LHKRQGSPRS FGGMSNKRLK PDFQRSLQRM PSSGRYS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)