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AT1G35670.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31520498 (2020): mitochondrion
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:21166475 (2011): cytosol
  • PMID:17317660 (2007): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : calcium-dependent protein kinase 2
Curator
Summary (TAIR10)
Encodes a Ca(2+)-dependent, calmodulin-independent protein kinase that is rapidly induced by drought and high-salt stress but not by low-temperature stress or heat stress. Positive regulator of ABA signaling. Phosphorylates ABA responsive transcription factors ABF1 and ABF4.
Computational
Description (TAIR10)
calcium-dependent protein kinase 2 (CDPK2); FUNCTIONS IN: calmodulin-dependent protein kinase activity, kinase activity; INVOLVED IN: response to water deprivation, response to salt stress, protein amino acid phosphorylation, positive regulation of abscisic acid mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 4 (TAIR:AT4G09570.1); Has 134131 Blast hits to 125244 proteins in 4234 species: Archae - 175; Bacteria - 14420; Metazoa - 49980; Fungi - 18055; Plants - 27559; Viruses - 606; Other Eukaryotes - 23336 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G35670-MONOMERBioGrid:25703EC:2.7.11.1eggNOG:ENOG410XRMJ
eggNOG:KOG0032EMBL:AC007887EMBL:AY050981EMBL:AY113986
EMBL:CP002684EMBL:D21806EnsemblPlants:AT1G35670EnsemblPlants:AT1G35670.1
entrez:840471Gene3D:1.10.238.10GeneID:840471Genevisible:Q39016
GO:GO:0004672GO:GO:0004674GO:GO:0004683GO:GO:0005509
GO:GO:0005516GO:GO:0005524GO:GO:0005634GO:GO:0005829
GO:GO:0005886GO:GO:0006468GO:GO:0009738GO:GO:0009789
GO:GO:0009931GO:GO:0018105GO:GO:0035556GO:GO:0046777
GO:GO:0080092GO:GO:1901979Gramene:AT1G35670.1hmmpanther:PTHR24349
hmmpanther:PTHR24349:SF166HOGENOM:HOG000233030InParanoid:Q39016IntAct:Q39016
InterPro:IPR000719InterPro:IPR002048InterPro:IPR008271InterPro:IPR011009
InterPro:IPR011992InterPro:IPR017441InterPro:IPR018247iPTMnet:Q39016
KEGG:ath:AT1G35670KO:K13412MINT:MINT-1788888OMA:SACTEFG
PaxDb:Q39016Pfam:PF00069Pfam:PF13499Pfam:Q39016
Pfscan:PS50011Pfscan:PS50222PIR:S46284PRIDE:Q39016
PRO:PR:Q39016PROSITE:PS00018PROSITE:PS00107PROSITE:PS00108
PROSITE:PS50011PROSITE:PS50222ProteinModelPortal:Q39016Proteomes:UP000006548
RefSeq:NP_174807.1scanprosite:PS00018scanprosite:PS00107scanprosite:PS00108
SMART:SM00054SMART:SM00220SMR:Q39016STRING:3702.AT1G35670.1
SUPFAM:SSF47473SUPFAM:SSF56112TAIR:AT1G35670tair10-symbols:ATCDPK2
tair10-symbols:ATCPK11tair10-symbols:CDPK2tair10-symbols:CPK11UniGene:At.24141
UniProt:Q39016
Coordinates (TAIR10) chr1:+:13205456..13208058
Molecular Weight (calculated) 55919.00 Da
IEP (calculated) 5.08
GRAVY (calculated) -0.36
Length 495 amino acids
Sequence (TAIR10)
(BLAST)
001: METKPNPRRP SNTVLPYQTP RLRDHYLLGK KLGQGQFGTT YLCTEKSTSA NYACKSIPKR KLVCREDYED VWREIQIMHH LSEHPNVVRI KGTYEDSVFV
101: HIVMEVCEGG ELFDRIVSKG HFSEREAVKL IKTILGVVEA CHSLGVMHRD LKPENFLFDS PKDDAKLKAT DFGLSVFYKP GQYLYDVVGS PYYVAPEVLK
201: KCYGPEIDVW SAGVILYILL SGVPPFWAET ESGIFRQILQ GKLDFKSDPW PTISEAAKDL IYKMLERSPK KRISAHEALC HPWIVDEQAA PDKPLDPAVL
301: SRLKQFSQMN KIKKMALRVI AERLSEEEIG GLKELFKMID TDNSGTITFE ELKAGLKRVG SELMESEIKS LMDAADIDNS GTIDYGEFLA ATLHMNKMER
401: EENLVAAFSY FDKDGSGYIT IDELQSACTE FGLCDTPLDD MIKEIDLDND GKIDFSEFTA MMRKGDGVGR SRTMMKNLNF NIADAFGVDG EKSDD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)