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AT3G44530.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25086063 (2014): nucleus nuclear matrix nucleolus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : homolog of histone chaperone HIRA
Curator
Summary (TAIR10)
Encodes a nuclear localized WD-repeat containing protein involved in negative regulation of knox gene expression via epigenetic mechanism of chromatin re-organization. Interacts physically and genetically with AS1. Expressed in meristem and leaf primordia. Homozygous mutants are embryo lethal. Phenotype of cosuppressed lines is variable but show effects on leaf development similar to as1/as2.
Computational
Description (TAIR10)
homolog of histone chaperone HIRA (HIRA); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), TUP1-like enhancer of split (InterPro:IPR011494), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G64630.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT3G44530EnsemblPlants:AT3G44530.1entrez:823578hmmpanther:PTHR13831
hmmpanther:PTHR13831:SF0Pfam:PF00400Pfam:PF07569Pfscan:PS50082
Pfscan:PS50294scanprosite:PS00678tair10-symbols:HIRA
Coordinates (TAIR10) chr3:+:16116026..16121247
Molecular Weight (calculated) 116497.00 Da
IEP (calculated) 6.84
GRAVY (calculated) -0.37
Length 1058 amino acids
Sequence (TAIR10)
(BLAST)
0001: MIAEKPFWVK HEGLQIFSID VQPNGERFAT GGGDHKVRIW NMKSVDKDLQ NIDTKERLLA TLRDHFGSVN CVRWAKNSRY VASGSDDQVI QIHERKPGSG
0101: TTEFGSGEAP DVENWKAVMT LRGHTADVVD LNWSPDDSML ASGSLDNTVH IWNMRTGMCT TVLRGHLSLV KGVTWDPIGS FIASQSDDKT VIIWRTSDWG
0201: MAHRTDGHWA KSLGSTFFRR LGWSPCGHFL TTTHGFQKPK HSAPVLERGE WSVAYDFLGH SAPIIVVRFN HSMFKRIPSS THETKQVGWS NGTSKSGEKD
0301: LQSYNVIAMG SQDRTITVWT TGSARPLFVA KHFFGQSVVD LSWSPDGYSL FACSLDGTVA MIHFDPKELG VRLTDTELDE LKKSRYGDVR GRQANLVESP
0401: AQLLLETAST KQAGSKRAAS DVQQNQVTTK PSVSVESTAK RRKSQVDDRN KAAESTGQTL NKASTLNRVS SPVNQKVYRR PDGRKRIIPE AVGVPQQENN
0501: IMINGESHNF LPASAAAPAK GDSGDFPVEI SNRDLSGKEI VCRNPDLKER SRITARATIT ESLVIEKVPG TSGRDGVLNV EQSVGIKESS STDLLIRVFD
0601: WKDGEAAPPV CLEACPREHA LDTVGAVSTS MVKETEISCK KSGETLWSDR IMGRVTVLAG NPNFWAAGCE DGSLQVYTKC GRRAMPTMMM GSAATFIDCD
0701: DSWKLLLVTR KGSLYVWDLF NRKCVLHDSL SSLVSSDVNL SSTVKVKRMK NWYLLIFLVG DLVVELLSWY EDSSVIDLDC TIKVISVKLS KSGSPLVVLA
0801: TRHAFLFDTS LMCWLRVADD CFPASNFSSS WNLGSAPCGE LAGLQVDVRK YMARKPGWNR ITDDGTQTRA HLESQLASSL ALESPNEYRQ CLLAYVRFLA
0901: READESRLRE VCESFLGPPT GMAEAASSDT NLSWDPYVLG VKKHKLLRND ILPAMASNRK VQRLLNEFID LLSEYEDVET ADPAPKGSTP TMNCGGVPSS
1001: LDQIGSDPPA MTATTPMTID NDKPVSLENP AALDIGVCEK TGSEDRDKQD QNSRDSGS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)