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AT5G55760.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28865150 (2017): extracellular region plant-type cell wall
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : sirtuin 1
Curator
Summary (TAIR10)
Encodes SRT1, a member of the SIR2 (sirtuin) family HDAC (histone deacetylase) (SRT1/AT5g55760, SRT2/AT5G09230).
Computational
Description (TAIR10)
sirtuin 1 (SRT1); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: protein amino acid deacetylation, chromatin silencing, regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: chromatin silencing complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 2 (TAIR:AT5G09230.7); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:20914EC:3.5.1.-eggNOG:COG0846eggNOG:KOG1905
EMBL:AB009050EMBL:AF283757EMBL:AK227432EMBL:BT008767
EMBL:CP002688EnsemblPlants:AT5G55760EnsemblPlants:AT5G55760.1entrez:835670
Gene3D:3.40.50.1220GeneID:835670Genevisible:Q9FE17GO:GO:0005634
GO:GO:0016787GO:GO:0046872GO:GO:0070403Gramene:AT5G55760.1
hmmpanther:PTHR11085hmmpanther:PTHR11085:SF20HOGENOM:HOG000231240InParanoid:Q9FE17
InterPro:IPR003000InterPro:IPR026590InterPro:IPR029035iPTMnet:Q9FE17
KEGG:ath:AT5G55760KO:K11416OMA:YIRTDFVPANTHER:PTHR11085
PaxDb:Q9FE17Pfam:PF02146Pfam:Q9FE17Pfscan:PS50305
PhylomeDB:Q9FE17PRIDE:Q9FE17PRO:PR:Q9FE17PROSITE:PS50305
ProteinModelPortal:Q9FE17Proteomes:UP000006548RefSeq:NP_200387.1SMR:Q9FE17
STRING:3702.AT5G55760.1SUPFAM:SSF52467TAIR:AT5G55760tair10-symbols:SRT1
UniGene:At.20180UniProt:Q9FE17
Coordinates (TAIR10) chr5:+:22567282..22570716
Molecular Weight (calculated) 52644.90 Da
IEP (calculated) 8.37
GRAVY (calculated) -0.24
Length 473 amino acids
Sequence (TAIR10)
(BLAST)
001: MSLGYAEKLS FIEDVGQVGM AEFFDPSHLL QCKIEELAKL IQKSKHLVVF TGAGISTSCG IPDFRGPKGI WTLQREGKDL PKASLPFHRA MPSMTHMALV
101: ELERAGILKF VISQNVDGLH LRSGIPREKL SELHGDSFME MCPSCGAEYL RDFEVETIGL KETSRKCSVE KCGAKLKDTV LDWEDALPPK EIDPAEKHCK
201: KADLVLCLGT SLQITPACNL PLKCLKGGGK IVIVNLQKTP KDKKANVVIH GLVDKVVAGV MESLNMKIPP YVRIDLFQII LTQSISGDQR FINWTLRVAS
301: VHGLTSQLPF IKSIEVSFSD NHNYKDAVLD KQPFLMKRRT ARNETFDIFF KVNYSDGCDC VSTQLSLPFE FKISTEEHVE IIDKEAVLQS LREKAVEESS
401: CGQSGVVERR VVSEPRSEAV VYATVTSLRT YHSQQSLLAN GDLKWKLEGS GTSRKRSRTG KRKSKALAEE TKA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)