AT5G55760.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : sirtuin 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes SRT1, a member of the SIR2 (sirtuin) family HDAC (histone deacetylase) (SRT1/AT5g55760, SRT2/AT5G09230). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
sirtuin 1 (SRT1); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: protein amino acid deacetylation, chromatin silencing, regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: chromatin silencing complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 2 (TAIR:AT5G09230.7); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:+:22567282..22570716 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 52644.90 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 8.37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.24 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 473 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MSLGYAEKLS FIEDVGQVGM AEFFDPSHLL QCKIEELAKL IQKSKHLVVF TGAGISTSCG IPDFRGPKGI WTLQREGKDL PKASLPFHRA MPSMTHMALV 101: ELERAGILKF VISQNVDGLH LRSGIPREKL SELHGDSFME MCPSCGAEYL RDFEVETIGL KETSRKCSVE KCGAKLKDTV LDWEDALPPK EIDPAEKHCK 201: KADLVLCLGT SLQITPACNL PLKCLKGGGK IVIVNLQKTP KDKKANVVIH GLVDKVVAGV MESLNMKIPP YVRIDLFQII LTQSISGDQR FINWTLRVAS 301: VHGLTSQLPF IKSIEVSFSD NHNYKDAVLD KQPFLMKRRT ARNETFDIFF KVNYSDGCDC VSTQLSLPFE FKISTEEHVE IIDKEAVLQS LREKAVEESS 401: CGQSGVVERR VVSEPRSEAV VYATVTSLRT YHSQQSLLAN GDLKWKLEGS GTSRKRSRTG KRKSKALAEE TKA |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)