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AT5G22110.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : DNA polymerase epsilon subunit B2
Curator
Summary (TAIR10)
Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.
Computational
Description (TAIR10)
DNA polymerase epsilon subunit B2 (DPB2); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding; INVOLVED IN: DNA replication, DNA-dependent DNA replication; LOCATED IN: epsilon DNA polymerase complex, nucleus; EXPRESSED IN: embryo, male gametophyte, apical meristem, female gametophyte; CONTAINS InterPro DOMAIN/s: DNA polymerase epsilon, subunit B (InterPro:IPR016266), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 412 Blast hits to 394 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 125; Fungi - 144; Plants - 62; Viruses - 0; Other Eukaryotes - 81 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT5G22110-MONOMEREC:2.7.7.7eggNOG:ENOG410XP7NeggNOG:KOG3818
EMBL:BT022108EMBL:CP002688EnsemblPlants:AT5G22110EnsemblPlants:AT5G22110.1
entrez:832272GeneID:832272GO:GO:0003677GO:GO:0003887
GO:GO:0006261GO:GO:0008622GO:GO:0042276Gramene:AT5G22110.1
hmmpanther:PTHR12708hmmpanther:PTHR12708:SF0HOGENOM:HOG000265254InterPro:IPR007185
InterPro:IPR016266KEGG:00230+2.7.7.7KEGG:00240+2.7.7.7KEGG:ath:AT5G22110
KO:K02325OMA:FAFKVYIPfam:PF04042PhylomeDB:Q500V9
PIRSF:PIRSF000799Proteomes:UP000006548Reactome:R-ATH-174430Reactome:R-ATH-68952
Reactome:R-ATH-68962RefSeq:NP_680197.2STRING:3702.AT5G22110.1TAIR:AT5G22110
tair10-symbols:ATDPB2tair10-symbols:CYL2tair10-symbols:DPB2UniGene:At.44338
UniGene:At.45633UniProt:Q500V9
Coordinates (TAIR10) chr5:-:7331071..7334178
Molecular Weight (calculated) 59542.80 Da
IEP (calculated) 5.29
GRAVY (calculated) -0.30
Length 526 amino acids
Sequence (TAIR10)
(BLAST)
001: MSSTSQKRKK IQKKFKNRGY NLKFDALDEI LVFADQFPDD DDGEAIDLLL DNLQETHKSS TVDAESVRGL INRLLGAHNA PEEPTTSASS LAIIDAFLVP
101: KFGYDSVKKK FNEHTSSLPI HGEASAKTAL YRERFMLLSQ RVSRAEHFSR PAFDAEMSQF ENNEISSIQS LISQRGRKWV MGVISQLEDG HFYLEDLSAS
201: VEIDLSKAKI TTGFFTENTI ILAEGEMQVN GIFQVITCGF PPLEDRDKTL KAHSEYDFFG GGTLTKEEMI KLADLERQAV NDTFVILSDI WLDDEEVMRK
301: LETVLDGFES VETVPSLFVF MGNFCSRPCN LSFGSYSSLR EQFGKLGRMI GNHPRLKENS RFLFIPGPED AGPSTVLPRC ALPKYLTEEL RNIIPNAIFS
401: SNPCRVKFYN QEIVFFRQDL LYRMRRSCLV TPSSEETNDP FKHLVYTITH QSHLCPLPLM VQPIIWNYDH ALRLYPTPHT IVLGDKSEQE VCKFGGTTCF
501: NPGSFSTDST FVAYRPSTQE VELSAL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)