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AT4G00020.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : BREAST CANCER 2 like 2A
Curator
Summary (TAIR10)
Ortholog of breast cancer susceptibility protein 2. Essential at meiosis. Interacts with either AtRad51 or AtDmc1 and ATDSS1(I). Involved in embryo sac development.
Computational
Description (TAIR10)
BREAST CANCER 2 like 2A (BRCA2(IV)); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis, embryo sac morphogenesis, embryo sac development, embryo development ending in seed dormancy; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BRCA2-like B (TAIR:AT5G01630.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:13519DIP:DIP-59496NeggNOG:ENOG410Y06WeggNOG:KOG4751
EMBL:AF069299EMBL:AJ488304EMBL:AL161471EMBL:CP002687
EnsemblPlants:AT4G00020EnsemblPlants:AT4G00020.1entrez:828230ExpressionAtlas:Q7Y1C5
Gene3D:2.40.50.140GeneID:828230Genevisible:Q7Y1C5GO:GO:0000724
GO:GO:0003677GO:GO:0051321hmmpanther:PTHR11289hmmpanther:PTHR11289:SF0
HOGENOM:HOG000083050IntAct:Q7Y1C5InterPro:IPR002093InterPro:IPR012340
InterPro:IPR015187InterPro:IPR015252InterPro:IPR015525iPTMnet:Q7Y1C5
PANTHER:PTHR11289PaxDb:Q7Y1C5Pfam:PF00634Pfam:PF09103
Pfam:PF09169Pfam:Q7Y1C5Pfscan:PS50138PhylomeDB:Q7Y1C5
PIR:A85001PIR:T01330PRIDE:Q7Y1C5PRO:PR:Q7Y1C5
PROSITE:PS50138ProteinModelPortal:Q7Y1C5Proteomes:UP000006548RefSeq:NP_191913.3
SMR:Q7Y1C5STRING:3702.AT4G00020.2SUPFAM:SSF50249SUPFAM:SSF81872
SUPFAM:SSF81878TAIR:AT4G00020tair10-symbols:BRCA2(IV)tair10-symbols:BRCA2A
tair10-symbols:EDA20tair10-symbols:MEE43UniGene:At.33529UniProt:Q7Y1C5
Coordinates (TAIR10) chr4:-:4107..10364
Molecular Weight (calculated) 126659.00 Da
IEP (calculated) 8.71
GRAVY (calculated) -0.37
Length 1151 amino acids
Sequence (TAIR10)
(BLAST)
0001: MSTWQLFPDS SGDGFRWEVA GRILQSVSDS TPTKALESTA PLPSMADLLL QGCSKLIARE EAMPGEIPMF RTGLGKSVVL KESSIAKAKS ILAEKVTYSD
0101: LRNTNCSIPQ MRQVDTAETL PMFRTASGKS VPLKESSIAK AMSILGSDKI IDSDNVLPRE SGFGVSNSLF QTASNKKVNV SSAGLARAKA LLGLEEDDLN
0201: GFNHVNQSSS SSQQHGWSGL KTHEEFDATV VKHHSGTPGQ YEDYVSGKRS EVLNPSLKVP PTKFQTAGGK SLSVSAEALK RARNLLGDPE LGSFFDDVAG
0301: GDQFFTPEKD ERLSDIAINN GSANRGYIAH EEKTSNKHTP NSFVSPLWSS SKQFSSVNLE NLASGGNLIK KFDAAVDETD CALNATHGLS NNRSLASDMA
0401: VNNSKVNGFI PRGRQPGRPA DQPLVDITNR RDTAYAYNKQ DSTQKKRLGK TVSVSPFKRP RISSFKTPSK KHALQASSGL SVVSCDTLTS KKVLSTRYPE
0501: KSPRVYIKDF FGMHPTATTR MDYVPDHVRR IKSSNADKYV FCDESSSNKV GAETFLQMLA ESGASLQHAS RKWVTNHYRW IVWKLACYDI YYPAKCRGNF
0601: LTITNVLEEL KYRYEREVNH GHCSAIKRIL SGDAPASSMM VLCISAINPK TDNDSQEAHC SDSCSNVKVE LTDGWYSMNA ALDVVLTKQL NAGKLFVGQK
0701: LRILGAGLSG WATPTSPLEA VISSTICLLL NINGTYRAHW ADRLGFCKEI GVPLALNCIK CNGGPVPKTL AGIKRIYPIL YKERLGEKKS IVRSERIESR
0801: IIQLHNQRRS ALVEGIMCEY QRGINGVHSQ NDTDSEEGAK IFKLLETAAE PEFLMAEMSP EQLRSFTTYK AKFEAAQQMR KEKSVAETLE DAGLGERNVT
0901: PFMRIRLVGL TSLSYEGEHN PKEGIVTIWD PTERQRTELT EGKIYMMKGL VPINSDSEIL YLHARGSSSR WQPLSPKDSE NFQPFFNPRK PISLSNLGEI
1001: PLSSEFDIAA YVVYVGNAYT DVLQKKQWVF VTDGSAQHSG EISNSLLAIS FSTSFMDDSS VSHISHNLVG SVVGFCNLIK RAKDVTNEIW VAEAAENSVY
1101: FINAEAAYSS HLKTSSAHIQ TWAKLSSSKS VIHELRQRVL SIIGACKSPS C
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)