AT4G00020.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : BREAST CANCER 2 like 2A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Ortholog of breast cancer susceptibility protein 2. Essential at meiosis. Interacts with either AtRad51 or AtDmc1 and ATDSS1(I). Involved in embryo sac development. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
BREAST CANCER 2 like 2A (BRCA2(IV)); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis, embryo sac morphogenesis, embryo sac development, embryo development ending in seed dormancy; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BRCA2-like B (TAIR:AT5G01630.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr4:-:4107..10364 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 126659.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 8.71 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 1151 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
0001: MSTWQLFPDS SGDGFRWEVA GRILQSVSDS TPTKALESTA PLPSMADLLL QGCSKLIARE EAMPGEIPMF RTGLGKSVVL KESSIAKAKS ILAEKVTYSD 0101: LRNTNCSIPQ MRQVDTAETL PMFRTASGKS VPLKESSIAK AMSILGSDKI IDSDNVLPRE SGFGVSNSLF QTASNKKVNV SSAGLARAKA LLGLEEDDLN 0201: GFNHVNQSSS SSQQHGWSGL KTHEEFDATV VKHHSGTPGQ YEDYVSGKRS EVLNPSLKVP PTKFQTAGGK SLSVSAEALK RARNLLGDPE LGSFFDDVAG 0301: GDQFFTPEKD ERLSDIAINN GSANRGYIAH EEKTSNKHTP NSFVSPLWSS SKQFSSVNLE NLASGGNLIK KFDAAVDETD CALNATHGLS NNRSLASDMA 0401: VNNSKVNGFI PRGRQPGRPA DQPLVDITNR RDTAYAYNKQ DSTQKKRLGK TVSVSPFKRP RISSFKTPSK KHALQASSGL SVVSCDTLTS KKVLSTRYPE 0501: KSPRVYIKDF FGMHPTATTR MDYVPDHVRR IKSSNADKYV FCDESSSNKV GAETFLQMLA ESGASLQHAS RKWVTNHYRW IVWKLACYDI YYPAKCRGNF 0601: LTITNVLEEL KYRYEREVNH GHCSAIKRIL SGDAPASSMM VLCISAINPK TDNDSQEAHC SDSCSNVKVE LTDGWYSMNA ALDVVLTKQL NAGKLFVGQK 0701: LRILGAGLSG WATPTSPLEA VISSTICLLL NINGTYRAHW ADRLGFCKEI GVPLALNCIK CNGGPVPKTL AGIKRIYPIL YKERLGEKKS IVRSERIESR 0801: IIQLHNQRRS ALVEGIMCEY QRGINGVHSQ NDTDSEEGAK IFKLLETAAE PEFLMAEMSP EQLRSFTTYK AKFEAAQQMR KEKSVAETLE DAGLGERNVT 0901: PFMRIRLVGL TSLSYEGEHN PKEGIVTIWD PTERQRTELT EGKIYMMKGL VPINSDSEIL YLHARGSSSR WQPLSPKDSE NFQPFFNPRK PISLSNLGEI 1001: PLSSEFDIAA YVVYVGNAYT DVLQKKQWVF VTDGSAQHSG EISNSLLAIS FSTSFMDDSS VSHISHNLVG SVVGFCNLIK RAKDVTNEIW VAEAAENSVY 1101: FINAEAAYSS HLKTSSAHIQ TWAKLSSSKS VIHELRQRVL SIIGACKSPS C |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)